Evaluation of the Current State of Aquatic Ecosystems and the Problems of the Protection of Biological Resources during Development of Kruzenshternskoye GCF

The results of studies of the current state of freshwater ecosystems and their biotic components in the western part of the Yamal Peninsula are presented in the article. Based on the evaluation of the structure of communities of phytoplankton, zooplankton, benthos, and whitefishes, the range of problems related to the protection of biological resources during the development of the Kruzenshternskoye gas field is defined. The data on species composition and quantitative indicators of hydrobionts of different types of waterbodies and watercourses in the lower reaches of the Mordyyakha and Naduyyakha Rivers basins is the basis for environmental monitoring of water objects during development and exploitation of the Kruzenshternskoye gas field.Estimation of the fish fauna state and their food base in the territory of the Kruzenshternskoye GCF according to the monitoring program is present. The river delta zones are the most important feeding areas of the salmonid and whitefishes valuable fish species in the territory of Kruzenshternskoye GCF. In cases where water bodies and watercourses are not completely demolished for the construction of GCF facilities, changes of quantitative and qualitative characteristics of communities of hydrobionts after the end of operations are reversible. River ecosystems are restored within a shorter period of time in comparison to lacustrine ones.Proposals for the protection of fisheries resources and monitoring of aquatic ecosystems on the basis of comprehensive studies are reported. Recommendations on reducing the anthropogenic impact on aquatic ecosystems in the development period are present. The results of the investigation were used in the development of the environmental protection part of the Kruzenshternskoye deposit project. Anthropogenic disturbances present now on the gas deposit territory of Kruzenshternskoye does not influence the aquatic ecosystems

Effect of once-yearly zoledronic acid on the spine and hip as measured by quantitative computed tomography: results of the HORIZON Pivotal Fracture Trial.

Changes in bone mineral density and bone strength following treatment with zoledronic acid (ZOL) were measured by quantitative computed analysis (QCT) or dual-energy X-ray absorptiometry (DXA). ZOL treatment increased spine and hip BMD vs placebo, assessed by QCT and DXA. Changes in trabecular bone resulted in increased bone strength. INTRODUCTION: To investigate bone mineral density (BMD) changes in trabecular and cortical bone, estimated by quantitative computed analysis (QCT) or dual-energy X-ray absorptiometry (DXA), and whether zoledronic acid 5 mg (ZOL) affects bone strength. METHODS: In 233 women from a randomized, controlled trial of once-yearly ZOL, lumbar spine, total hip, femoral neck, and trochanter were assessed by DXA and QCT (baseline, Month 36). Mean percentage changes from baseline and between-treatment differences (ZOL vs placebo, t-test) were evaluated. RESULTS: Mean between-treatment differences for lumbar spine BMD were significant by DXA (7.0%, p < 0.01) and QCT (5.7%, p < 0.0001). Between-treatment differences were significant for trabecular spine (p = 0.0017) [non-parametric test], trabecular trochanter (10.7%, p < 0.0001), total hip (10.8%, p < 0.0001), and compressive strength indices at femoral neck (8.6%, p = 0.0001), and trochanter (14.1%, p < 0.0001). CONCLUSIONS: Once-yearly ZOL increased hip and spine BMD vs placebo, assessed by QCT vs DXA. Changes in trabecular bone resulted in increased indices of compressive strength