STUDI PERBANDINGAN PERSEPSI KUALITAS LAYANAN ONLINE PENGGUNA OVO DAN GO-PAY DI SURABAYA TIMUR

Penelitian ini bertujuan untuk mengetahui persepsi masyarakat terhadap penggunaan financial technology (Fintech). Informan dalam penelitian ini adalah informan pelaku, yaitu masyarakat Kota Surabaya Timur yang menggunakan ataupun tidak menggunakan fintech. Teknik pengumpulan data menggunakan metode indepthinterview kepada 10 informan dilatar belakangi usia dan profesi yang berbeda. Teknik analisa yang digunakan adalah metode deskriptif kualitatif yang berguna untuk memberikan fakta dan data. Hasil penelitian menunjukkan bahwa persepsi masyarakat terhadap penggunaan financial technology (fintech) meliputi sikap,minat, pemahaman, dan harapan. Dimana sikap masyarakat terhadap penggunaan fintech, memberikan dukungan kepada kemajuan inovasi teknologi keuangan di Indonesia yang sangat membantu masyarakat, sedangkan minat masyarakat untuk menggunakan fintech sudah terbukti dari hasil wawancara dari 10 responden sudah berminat menggunakannya. Masyarakat sudah begitu memahami manfaat dan penggunaan fintech karena penggunaan fintech lebih efisien dan efektif dibandingkan jasa keuangan lainnya sehingga masyarakat termotivasi untuk menggunakan fintech. Dan harapan masyarakat kepada penyelenggara fintech agar memberikan sosialisasi kepada masyarakat dan kemudahaan atau kepraktisan dalam menggunakan layanan, sehingga masyarakat yang kurang memahami teknologi dapat menggunakannya dengan mudah

End of life care: the importance of advance care planning

Background: Communication about end of life care may involve difficult conversations for patients, family members and health professionals. However, a lack of understanding of a person\u27s wishes about their future care may result in a loss of dignity for the person, and additional distress for their family members and health professionals and burden to the healthcare system. Objective: This article discusses the barriers to advance care planning and provides some guidance for the general practitioner in undertaking advance care planning with patients and their families. Tips for initiating end of life discussions with patients and families utilising the \u27PREPARED\u27 acronym, and ensuring appropriate care delivery are included. Discussion: Involving patients and their family members in advance care planning may be challenging and time consuming for GPs. However, there are a number of resources to support this activity in relation to training, communication support and Medicare item funding

The association between frailty and anxiety: A systematic review

OBJECTIVES: Previous systematic reviews show a clear relationship between frailty and depression, however the association with anxiety is much less frequently explored. Previous single studies indicate evidence is mixed. We completed a systematic review and meta-analysis to identify the relationship between frailty and anxiety. METHODS: We searched five electronic databases for observational studies in older people in community, care home and outpatient settings with any/no health conditions that measured the association between anxiety and frailty using validated measures. Studies were screened by one reviewer with 10% checked by a second reviewer. The Mixed Methods Appraisal Tool was used to assess study quality. We used meta-analysis to aggregate study findings, with subgroup analyses to explore heterogeneity. RESULTS: Out of 1272 references, a total of 20 cross-sectional and 1 longitudinal studies were eligible. Older adults with frailty were substantially more likely to display anxiety symptoms than robust populations, across both dichotomous and continuous data sets (n = 10, OR = 3.48, 95% CI: 2.08, 5.81, p < 0.0001, I2  = 94%; N = 5, SMD = 3.13, 95% CI: 1.06, 5.21, I2  = 98%). Similarly, pre-frail older adults were more likely to have anxiety symptoms than robust older adults but to a lesser extent (N = 6, OR = 1.95, 95% CI: 1.41, 2.71, I2  = 63%; N = 3, SMD = 1.70, 95% CI: 0.01, 3.38, I2  = 98%). CONCLUSIONS: There is a clear association between pre-frailty/frailty and anxiety in older adults. However, data are heterogeneous and primarily from cross-sectional studies so causality cannot be determined. Future research should evaluate the effectiveness of anxiety screening and treatments in frail older adults

Participation of Students With Disabilities in Higher Education: Policy and Practices Melissa Ng Lee Yen Abdullah, School of Educational Studies,

Equity, in general refers to fairness or justice. The promotion of equity through policies and practices requires the individuals’ or groups’ needs and circumstances to be taken into account (Matear, 2006). Access to higher education should not be taken out of the context of equity (Asian Development Bank, 2012). Policy on equitable access, therefore, seeks to provide students with disabilities with greater opportunities to access tertiary education, which is driven by a sense of justice and fairness. Students with disabilities are still underrepresented in higher education at most countries, particularly in developing countries. Based on the policy and practices in developed countries, this paper aims to reflect on the provision of equitable higher education for students with disabilities at a selected developing country

Management of Ovarian Cancer — Is There a Role for Cytoreductive Surgery (CRS) and Hyperthermic Intraperitoneal Chemotherapy (HIPEC)?

Ovarian cancer is one of the commonest malignancy in women worldwide, and is the most lethal of all the gynaecological malignancies. Ovarian cancer often presents at an advanced stage, with the involvement of the peritoneal surface either at the initial diagnosis or at recurrence. Despite the advances made in the surgical techniques and chemotherapeutic options regarding agents, schedule, and route of administration, majority of the patients recur and eventually succumb to their disease. The change in the surgical approach supporting more radical and extensive surgical procedures, in a bid to attain optimal cytoreduction with no gross residual disease, has seen improvement in the survival, as has the use of intraperitoneal chemotherapy in combination with i.v. agents. Although peritoneal carcinomatosis has always been a poor prognostic factor, it ceases to be a factor of much importance if complete cytoreduction can be achieved. Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) provide the combined benefits of surgical eradication and effective chemotherapy, and can be performed with acceptable morbidity and mortality. Further trials are being undertaken to examine its role in the primary, as well as recurrent settings of advanced ovarian cancer and to determine the ideal drug combinations and dosages. We aim to discuss the role of CRS and HIPEC in the treatment of ovarian cancer

A Case of Lung Cancer with Isolated Skip Metastasis to an External Iliac Lymph Node

Introduction: Isolated skip metastases to intra-abdominal lymph nodes from lung cancer are rare and management of such disease remains controversial.  Presentation of case: We report a case of lung adenocarcinoma in the right upper lobe with isolated lymph node metastasis to an external iliac lymph node detected by Positron Emission Tomography (PET) scan which was confirmed histopathologically.  Conclusion: Isolated intra-abdominal lymph nodes from lung cancer are a rare occurrence.  In these patients, lymphadenectomy can be considered together with definitive treatment of the lung primary

Effect of heavy metal contamination on the DNA Mutation on Nepenthes plant from abandoned mine

Objective: Heavy metal contamination on water, soil, crops and including to the other living organisms, including their effects on DNA mutation in abandoned mine is highlighted in this study Methodology: In this study, 6 toxic metals, Zn, Pb, Fe, Cd, Cr and Mn in Nepenthes plants at an abandoned copper mine site were investigated. A total of 20 Nepenthes plants were collected from different sites of the abandoned mine. Metal concentration was determined using the Inductively Coupled Plasma/Optical Emission Spectrometry (ICP/OES) technique and electrophoresis gel and Inter Simple Sequence Repeat (ISSR) amplification processes for DNA mutation analysis. The total concentration trend of metal concentrations recorded with Cu (up to 88.797 mg kg–1)>Mn (39.018 mg kg–1)>Zn (30.260 mg kg–1)>Pb (8.206 mg kg–1)>Cd (0.168 mg kg–1). Results: The results also showed that concentration of heavy metals in Nepenthes plants collected from the abandoned mine were much higher than in control plants. However, the concentrations were still under the tolerance limit of heavy metals in plants except for Cu concentration. Besides, the concentration of heavy metals generally is higher in the flowers of the plants. For DNA analysis, based on the image obtained the result showed the DNA bands were located at the same location with the control Nepenthes which indicated there is no mutation occurred for the Nepenthes collected from the abandoned mine. Conclusion: From the result it is suggested that pitcher plant such Nepenthes may act as a potential phytoextraction of heavy metal from contaminated soil or water compounds at the abandoned mine

Computational Study of Hydrogel Ring Device for Ocular Drug Delivery

Researchers have developed many different kinds of ocular drug delivery devices. However, most address anterior eye disorders—very few are designed specifically for the treatment of posterior eye diseases. A recently-developed hydrogel ring device is capable of delivering therapeutic quantities of the drug Ofloxacin to treat ocular infections at the back of the eye—a region typically difficult to access via systemic (e.g. ingestion of pills) and topical (e.g. eye drops) methods. Despite promising preliminary in vivo test results, much remains unknown about the precise drug transport pathway from the hydrogel ring to the posterior segment of the eye, as well as how design parameters may be altered to increase drug delivery efficiency. The aim of this work is to fully characterize the drug release and transport characteristics from the hydrogel, to ocular tissues (anterior and posterior), as well as provide a quantitative method for the optimization of various hydrogel ring design parameters. To achieve the abovementioned goals, we built a computational model using COMSOL Multiphysics to simulate the release of Ofloxacin from the hydrogel ring and to obtain the resulting drug distribution in ocular tissues at various time points. Using the model, we monitored the transient Ofloxacin concentration profile over the entire eye, for a treatment period of ten hours. Our results showed that while Ofloxacin diffuses to the anterior region much more quickly than to posterior tissues, Ofloxacin concentrations do successfully accumulate to therapeutic levels in the posterior tissues during the simulated ten-hour treatment period. This finding supports the therapeutic potential of the hydrogel ring for the treatment of posterior eye diseases. We also performed optimization analyses to determine the ideal set of hydrogel ring design parameters for the treatment of infections caused by three bacterial species commonly associated with ocular disorders: Escherichia coli, Staphylococcus aureus, and Streptococcus pneumoniae. Preliminary findings suggest that the combination of an initial mass of 3 mg/m3 of Ofloxacin in the hydrogel and an Ofloxacin diffusivity of 3.11X10−9 m2/s in the hydrogel provide the best possible therapeutic outcome (from the range of values tested) for the treatment of E. coli and S. aureus infections. To our best knowledge, there is no existing computational model that simulates drug transport through the entire human eye from an ocular drug delivery device. We believe that our computational model will be highly useful for quantitative device characterization of the hydrogel ring, as well as in the optimization of the hydrogel ring design for the treatment of posterior eye disorders. This work may also serve as a model and reference for future computational work on ocular pharmacokinetics and/or ocular drug delivery devices