Duration of Breastfeeding in Late Preterm Infants:Maternal and Infant Factors

Background More than 550,000 late preterm infants are born each year in Indonesia. These infants, born between 34(0/7)-36(6/7) weeks, have more complications than term infants. Breastfeeding is considered the most optimal nutrition for newborn infants. Two groups of factors are important for successful breastfeeding: infant and maternal factors. The infant factors can be evaluated using the Infant Breastfeeding Assessment Tool and the maternal aspects with the Breastfeeding Self-Efficacy Scale-Short Form. Aim To determine whether the Infant Breastfeeding Assessment Tool or the Breastfeeding Self-Efficacy Scale-Short Form was more predictive of successful breastfeeding among late preterm infants. Methods This study was conducted in the Academic Teaching Hospital in Surabaya, Indonesia in March-July 2017. Mothers who delivered their infant between a gestational age of 34(0/7) and 36(6/7) weeks were included. Results Fifty-four single born participant mother-infant pairs were included. The mean total Breastfeeding Self-Efficacy Scale-Short Form score was 57.8 (SD = 8.9). The mean Infant Breastfeeding Assessment Tool score was 8.3 (SD = 1.8). There was a significant correlation between the total Breastfeeding Self-Efficacy Scale-Short Form score and the Infant Breastfeeding Assessment Tool score (p = .020, r = 0.316). The Breastfeeding Self-Efficacy Scale-Short Form was significantly higher in the participant (mothers) of the infants breastfed >= 4 months, compared to < 4 months, 61.59 (SD = 5.78) versus 51.78 (SD = 11.64; p = .001). No correlation was found between the duration of breastfeeding and Infant Breastfeeding Assessment Tool score (p = .087) Conclusion Maternal factors were more important for successful breastfeeding in these late preterm infants than infant factors in our sample

PERBEDAAN KOMPONEN SINDROMA METABOLIK PADA PASIEN DIABETES MELLITUS TIPE 2 DENGAN PENYAKIT JANTUNG KORONER (PJK) DAN NON PJK

Background:. The increasing of blood glucose levels or hyperglycemia is one of the characterization of type 2 diabetes which is caused by insulin resistance. Uncontrolled hyperglycemia causes macrovascular complications such as cardiovascular disease and stroke. The components of the metabolic syndrome is associated with the occurrence of type 2 diabetes and coronary heart disease. However, type 2 diabetes patient without metabolic syndrome will not increase the prevalence of CHD compared to those with metabolic syndrome. This study aims to determine differences of the metabolic syndrome components on type 2 diabetes patients within Coronary Heart Disease (CHD) and non CHD. Methods: The method of this research is a cross-sectional study. Data directly collected from type 2 diabetes outpatients in Endocrinology polyclinic of RSUD Dr. Soetomo from January until August 2016. We divided the samples into two groups: type 2 diabetes patients with CHD group and type 2 diabetes patients non-CHD group. Those groups are being observed focusing on the differences of metabolic syndrome components that includes waist circumference, triglycerides , HDL cholesterol, LDL cholesterol, blood pressure, fasting plasma glucose, and HbA1c. Kolmorgrov-Smirnov used to test the data normalities then followed by Independent Sample T-Test or Mann Whitney test to determine the significance of its differences. Results: Independent sample T-Test of triglycerides, LDL-C and waist circumference has a p-value = 0.776; 0.101; 0.206 respectively (p>0,005). While Indepedent sample T-test of HDL-C and HbA1c have p-value 0,028 and 0,000 (p 0.05). Conclusions:This research found that there is significant diferences of value in HDL-C and HbA1c on type 2 diabetes patients who has coronary heart disease. On the other hand, there are no significant differences of value in triglycerides, LDL-C, fasting blood glucose, waist circumference and blood pressure on type 2 diabetes patient who has coronary heart disease and non-CHD

RADIOTHERAPY EFFECT ON COMPLETE BLOOD COUNT PARAMETER IN PATIENTS WITH NASOPHARYNGEAL CARCINOMA

Abstract Introduction: Nasopharyngeal carcinoma (NPC) is the most common malignant tumor of the nasopharynx. Radiotherapy is a therapy of choice for NPC that has been recognized for a long time and used in various centers of the world. However, radiotherapy is known to still have an adverse effect. It is common practice to evaluate Complete Blood Count (CBC) before, during, and after radiotherapy. However, there has been no study regarding the effect of radiotherapy on all CBC parameters. This study aims to analyze the effect of radiotherapy on CBC in NPC patients before and after radiotherapy treatment. Material and methods: This study was an observational study using secondary data from medical records at the radiotherapy outpatient clinic at Dr. Soetomo General Hospital Surabaya. The subject of this study was patients with NPC who underwent a full cycle of radiotherapy treatment on radiotherapy outpatient clinic in 2016. Patients with incomplete medical records and did not finish the radiotherapy treatment were excluded. A paired T-test and Wilcoxon signed-rank test were used for statistical analysis. Results: There were 105 patients included in this study. Mean Corpuscular Hemoglobin Concentration (MCHC), total leucocyte, lymphocyte, and thrombocyte was significantly decreased after a full cycle of radiotherapy (all p <0.05). Eosinophil, basophil, neutrophil, monocyte, Neutrophil to Lymphocyte ratio (NLR), and Platelet to Lymphocyte ratio (PLR) was significantly increased after a full cycle of radiotherapy (all p <0.05). Conclusion: Radiotherapy had a significant effect on the CBC parameter in NPC patients

Clinical Presentation of Nasopharyngeal Carcinoma in East Java,Indonesia

Abstract Background: Nasopharyngeal Carcinoma (NPC) is a rare malignancy throughout most of the world, but the incidence in Southeast Asia is very high. In Indonesia, NPC is the fourth most common malignancy. Among all regions in Indonesia, East Java has the highest incidence. However, there is no detailed study in East Java regarding this malignancy. Aim: To document the clinical presentation of NPC in East Java. Methodology: This was a descriptive study using medical record at Dr. Soetomo General Hospital. Samples were newly diagnosed NPC patients who attended radiotherapy outpatient clinic between January – December 2016. Total sampling method was used in this study. Patients’ characteristic including presented symptoms, chief complaints, clinical staging, and histological subtypes were assessed and evaluated. Results: There were 270 NPC patients registered in radiotherapy outpatients clinic at Dr. Soetomo General Hospital in 2016. Two-thirds of the patients were male. More than half of the patients came to the healthcare service with the chief complaint of lump in the neck. Based on the staging, almost all patients were already in the late stage. Histopathologic findings showed that WHO type 3 was the most common subtypes of NPC.\ Conclusion: Majority of the NPC patients in East Java were already in the advanced stage. Early diagnosis is important for favorable outcome of this disease. Thus, it is important to understand the chief complaint and symptoms in patients with NPCso that the diagnostic delay could be avoided

Gambaran Klinis dan Karakteristik Neonatus dari Ibu Terkonfimasi Covid-2019 di Rumah Sakit Dr. Soetomo

Latar belakang. Penyakit Coronavirus 2019 (COVID-19) merupakan penyakit yang pertama kali dilaporkan di Wuhan, China dan telah menyebar ke seluruh dunia. Data ibu hamil dan bayi baru lahir belum banyak dipublikasikan. Tujuan. Untuk mendeskripsikan gambaran dan karakteristik klinis neonatus yang lahir dari ibu dengan infeksi severe acute respiratory syndrome-coronavirus (SARS-CoV-2) perinatal. Metode. Penelitian ini merupakan penelitian retrospektif yang dilaksanakan di ruang perawatan neonatal intensive care unit (NICU) Rumah Sakit Umum Daerah Dr.Soetomo Surabaya pada tanggal April - Oktober 2020. Populasi adalah neonatus yang lahir dari ibu terkonfimasi COVID-19 di di Rumah Sakit Dr. Soetomo Surabaya. Data diperoleh dari rekam medik. Hasil. Total terdapat 109 ibu dengan hasil pemeriksaan positif reverse transcription - polymerase chain reaction (RT PCR) COVID-19, dan hanya 2 bayi dengan hasil RT-PCR COVID-19 positif. Usia rata-rata ibu hamil 28±5,9 tahun. Duapuluh sembilan bayi (26,61%) lahir kurang bulan. Cara persalinan didominasi oleh sectio caesaria sebanyak 64 ibu hamil (58,72%). Terdapat 23 bayi (21,11%) lahir dengan berat badan lahir <2500 gram dan 3 bayi dengan hasil negatif RT-PCR COVID-19 meninggal. Kesimpulan. Saat ini belum terbukti adanya penularan secara vertikal COVID 19, sementara itu transmisi horizontal diperkirakan sebagai sumber infeksi pada neonatus. Penerapan protokol kesehatan terbukti efektif mencegah infeksi terhadap neonatus