6 research outputs found

    The Assessment of Maxillofacial Soft Tissue and Intracranial Calcifications via Cone-beam Computed Tomography

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    Background: Cone-beam Computed Tomography (CBCT) scans obtained with larger field of view let us see various incidental findings, anatomical variations and pathologies, like intracranial and soft tissue calcifications

    Effects of taxifolin on bone formation and apoptosis in experimental periodontitis in diabetic rats

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    We investigated the therapeutic potential of taxifolin for treatment of alveolar bone loss (ABL) in experimental periodontitis in diabetic rats. Diabetes mellitus (DM) was induced by streptozotocin. Rats were divided into six groups: untreated control; DM only (D) group; ligature only (P) group; DM + ligature (DP) group; DM + ligature + 5 mg/kg/day taxifolin (Taxi-5) group; DM + ligature + 10 mg/kg/day taxifolin (Taxi-10) group. Experimental periodontitis was induced by ligation of the first molar and allowed to progress for 30 days before performing cone-beam computed tomographic (CBCT), histomorphometric and immunohistochemical analyses of periodontal tissue destruction. ABL was assessed using CBCT. ABL was greatest in the P and DP groups. Decreased ABL was observed in the Taxi-5 and Taxi-10 groups. Bone morphogenic protein (BMP-2), osteocalcin (OCN), receptor activator of nuclear factor kappa-Beta ligand (RANKL), alkaline phosphatase (ALP), type I collagen, B cell lymphoma-associated X (Bax), and B-cell lymphoma 2 (Bcl-2) levels were investigated using immunohistochemistry. The Taxi-5 and Taxi-10 groups exhibited decreased RANKL expression, but increased BMP-2, ALP, type I collagen and OCN levels compared to the P and DP groups. Bax activity was increased in the D, P and DP groups. Taxi-5 and Taxi-10 groups exhibited increased Bcl-2 activity. Our findings suggest that taxifolin can reduce apoptosis and improve alveolar bone formation in diabetic rats with periodontitis

    A LIFE-SAVING EARLY DIAGNOSIS OF BURKITT LYMPHOMA INVOLVING BOTH JAWS, MISDIAGNOSED AS PERICORONITIS

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    Burkitt lymphoma (BL) is a highly aggressive and rare B-cell non-Hodgkin's lymphoma. In this paper, a rare case of BL, involving both jaws, was presented. A 24-year-old male patient was referred to our clinic with the complaint of mandibular and maxillary swelling for two months. He was previously misdiagnosed with pericoronitis and had a history of the right mandibular third molar tooth extraction, one-month prior. Intraoral examination showed swelling, ulceration, and spontaneous bleeding in both jaws. Radiographically, extensive osteolytic lesions, irregular periodontal space widening, loss of lamina dura, and peri-radicular radiolucencies were detected. Incisional biopsy was performed from both jaws and the final diagnosis was made as BL. It is crucial to be aware of the clinical and radiological features of this disease dentists and to consult the withou
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