3 research outputs found

    Digitales Lernen an der Uni

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    Die Sendung ist in Kooperation mit der Redaktion CampusTV unter der Leitung von Oliver HĂ€ußler entstanden. 01 Wie kam das erste Online-Semester bei den TĂŒbinger Studentinnen und Studenten an? Ein Beitrag von Nicole Rebhun und Sarah Kmiecak. 02 Dass es wĂ€hrend Corona und dem digitalen Lernen durchaus auch kreativ zugehen kann, zeigt ein Kulturprojekt, bei dem auch einige Studierende aus TĂŒbingen mitgemacht haben. Es geht um VR-Erlebnisse, also virtuelle RĂ€ume speziell fĂŒr Museen. NĂ€mlich in Form eines Hakathons. Hackathon, das ist eine Art Worskshop, in dem die TeilnehmerInnen gemeinsam und simultan kreative Software entwickeln. Meistens zu einem bestimmten Thema – wie eben dem Museum. Jennifer Götzinger und Veronika Melchior berichten. 03 Reisen in ferne LĂ€nder. WĂ€hrend Corona: Fehlanzeige. Stattdessen sitzen wir zuhause am Rechner und versuchen online zu lernen. Doch aufgepasst. Auch in der Online-Lehre gibt es einige Fallstricke. Robin Andres und Nick Schindowski liefern Euch ein paar Tipps fĂŒr den Datenschutz. 04 Genau wie mit dem Datenschutz, steht der eine oder die andere auch der KĂŒnstlichen Intelligenz skeptisch gegenĂŒber. Die KI kann uns aber in der Online-Lehre sehr behilflich sein. Ein Beitrag von Melanie Musselmann, Fabian Groschulski und Vidian Prey

    Additive value of transarterial embolization to systemic sirolimus treatment in kaposiform hemangioendothelioma

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    Kaposiform hemangioendothelioma (KHE) is a rare vascular tumor in children, which can be accompanied by life-threatening thrombocytopenia, referred to as Kasabach-Merritt phenomenon (KMP). The mTOR inhibitor sirolimus is emerging as targeted therapy in KHE. As the sirolimus effect on KHE occurs only after several weeks, we aimed to evaluate whether additional transarterial embolization is of benefit for children with KHE and KMP. Seventeen patients with KHE and KMP acquired from 11 hospitals in Germany were retrospectively divided into two cohorts. Children being treated with adjunct transarterial embolization and systemic sirolimus, and those being treated with sirolimus without additional embolization. Bleeding grade as defined by WHO was determined for all patients. Response of the primary tumor at 6 and 12 months assessed by magnetic resonance imaging (MRI), time to response of KMP defined as thrombocyte increase >150 × 103/ÎŒL, as well as rebound rates of both after cessation of sirolimus were compared. N = 8 patients had undergone additive embolization to systemic sirolimus therapy, sirolimus in this group was started after a mean of 6.5 ± 3 days following embolization. N = 9 patients were identified who had received sirolimus without additional embolization. Adjunct embolization induced a more rapid resolution of KMP within a median of 7 days vs 3 months; however, tumor response as well as rebound rates were similar between both groups. Additive embolization may be of value for a more rapid rescue of consumptive coagulopathy in children with KHE and KMP compared to systemic sirolimus only
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