Comparison of Burn Depth at Different Temperatures on Ex Vivo Human Skin with Standardized Model and Comparison of the Results with Rat Contact Burn Model

Aim: Burns are still an important mortality and morbidity problem worldwide. Clinical studies are limited, owing to ethical concerns and an inability to achieve standardization. Therefore, studies are concentrated on experimental models. However, there are still a lot of questions that await resolution. Additionally, the relevance of animal models on human skin (HS) is unknown. From this point of view, this study aims to evaluate the depth of burn on ex vivo HS and to compare the HS results with those of rats. Materials and Methods: Skins of patients, after obtaining informed consent, that underwent full thickness healthy skin excision (abdominoplasty), except for experimental purposes, have been included. A total of three different temperatures (60, 80 and 100 °C) using two different weight forces (0.88 kg/cm2 for high and 0.21 kg/cm2 for low) using standardized apparatus facilitated the formation of study groups. In all groups, healthy dermis-epidermis burn depth was compared. Results: No difference was detected between healthy HS depths from the various samples taken from different donors that were to be tested. The lowest result (10.5±0.7% burn depth ) was seen in the 60 °C low weight force group and the highest was seen in the 100 °C high weight force group (92.0±2.7). As for the 80 °C high pressure group vs the 100 °C low pressure groups, a significant difference was noted. Conclusion: Ex vivo HS can be used as an experimental burn model. It has been shown that standardized depth of burn can be achieved using standardized apparatus. However, the different depth of burn indicates that control of parameters (pressure, time, temperature) is mandatory

Miyelodisplazili olgularda ürolojik sorunlar ve tedavileri: Retrospektif klinik araştırma

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A rare etiology for appendicitis, torsion of the vermiform appendix: Case report and review of the literature

Apandisit, fekalit, lenfoid hiperplazi, paraziter ve viral hastalıklar, yabancı cisim, kistik fibroz ve karsinoid tümör gibi nedenlerle, lumen obstrüksiyonu sonucu gelişen bir patolojidir. Apendiks vermiformisin torsiyonu da apandisite neden olan, literatürde sayılı olgu sunumları ile bildirilmiş, çok nadir görülen bir durumdur. İlk kez 1918 yılında Payne tarafından tarif edilmiştir. Tanı genellikle akut karın nedeniyle operasyon sırasında konur. Burada akut karın ön tanısıyla operasyona alınan ve apendiks vermiformis torsiyonu saptanan olgu literatür taraması ile birilikte sunuldu.Faeces, lymphoid hyperplasia, parasite or viral infection, foreign body, cystic fibrosis and carcinoid tumors are the reasons for intraluminal obstruction of appendix that cause appendicitis. Torsion of appendix vermiformis is the rare pathology that cause appendicitis with limited case reports in the literature. It was described for the first time in 1918 by Payne. It is generally diagnosed during the operation because of acute abdomen. In this study we would like to present torsion of appendix vermiformis that is detected during the operation cause of acute abdomen with review of literature

A rare etiology for appendicitis, torsion of the vermiform appendix: Case report and review of the literature

Apandisit, fekalit, lenfoid hiperplazi, paraziter ve viral hastalıklar, yabancı cisim, kistik fibroz ve karsinoid tümör gibi nedenlerle, lumen obstrüksiyonu sonucu gelişen bir patolojidir. Apendiks vermiformisin torsiyonu da apandisite neden olan, literatürde sayılı olgu sunumları ile bildirilmiş, çok nadir görülen bir durumdur. İlk kez 1918 yılında Payne tarafından tarif edilmiştir. Tanı genellikle akut karın nedeniyle operasyon sırasında konur. Burada akut karın ön tanısıyla operasyona alınan ve apendiks vermiformis torsiyonu saptanan olgu literatür taraması ile birilikte sunuldu.Faeces, lymphoid hyperplasia, parasite or viral infection, foreign body, cystic fibrosis and carcinoid tumors are the reasons for intraluminal obstruction of appendix that cause appendicitis. Torsion of appendix vermiformis is the rare pathology that cause appendicitis with limited case reports in the literature. It was described for the first time in 1918 by Payne. It is generally diagnosed during the operation because of acute abdomen. In this study we would like to present torsion of appendix vermiformis that is detected during the operation cause of acute abdomen with review of literature

Can a Small Intestine Segment Be an Alternative Biological Conduit for Peripheral Nerve Regeneration?

Background: Autologous nerve grafts are used to bridge peripheral nerve defects. Limited sources and donor site morbidity are the major problems with peripheral nerve grafts. Although various types of autologous grafts such as arteries, veins and muscles have been recommended, an ideal conduit has not yet been described