Interrupted inferior vena cava and partial anomalous pulmonary venous return with atrial septal defect in a 38-year-old adult: a case report

We present a woman having congenital anomalies of the inferior vena cava and partial anomalous pulmonary venous return from the right lung with atrial septal defect in a 38-year-old. Congenital anomalies of inferior vena cava are rare. They are seen more often in young males. If there are not other anomalies, they are latent for a long time. Peripheral venous thrombosis, chronic venous insufficiency, dyspnea and fatigue are often the first symptoms of these anomalies. Surgical repair of atrial septal defect with partial anomalous pulmonary venous return include provision of durably unobstructed systemic and pulmonary venous pathways, closure of the atrial septal defect, and avoidance of arrhythmias. The diagnosis has been determined by compression ultrasonography with color doppler assessment, multidetector computed tomography angiography and echocardiography

Citološka analiza endometrija kod krava s akutnim i kroničnim endometritisom.

The aim of the present study was to evaluate the findings of endometrial cytology in cows with acute and chronic endometritis. For this purpose samples were collected from 217 Brown Swiss and Holstein cows, housed on the Atatürk University Dairy Research Farm between the years 2010 and 2012, and they were stained with Giemsa for cytological examination. In the evaluation, overall 100 cells were counted in the microscopic area and the cells were classified as polymorph nuclear leukocyte, macrophage, lymphocyte and epithelial cells. The cytopathological classification was done according to the percentages of inflammatory cells. Briefly, 126 (58.06 %) samples had extensive inflammatory cells, and of the uterine samples 91 (41.94 %) had normal exfoliation. According to the cellular density results, acute, and chronic and subacute endometritis were described in 68 (31.33 %), 23 (10.60 %) and 35 (16.13 %) cases, respectively. In conclusion, endometrial cytology was found to be an applicable and reliable diagnostic method in diagnosis and diffentiation of acute and chronic endometritis.Cilj istraživanja bio je procijeniti citološke nalaze u endometriju krava s akutnim i kroničnim endometritisom. U tu su svrhu između 2010. i 2012. godine bili prikupljeni uzorci od 217 krava smeđe i holštajnske pasmine, uzgajanih na pokusnoj mliječnoj farmi na Sveučilištu Atatürk. Uzorci su bili obojeni Giemsinim bojenjem. Pri procjeni je u vidnom polju mikroskopa bilo izbrojeno ukupno 100 stanica kojesu razvrstane u polimorfononuklearne leukocite, makrofage, limfocite i epitelne stanice. Citopatološko razvrstavanje bilo je provedeno na osnovi postotka upalnih stanica. Ukratko, upalne stanice bile su ustanovljene u 126 (58,06 %) uzoraka, dok je u 91 (41,94 %) uzorku maternice ustanovljeno normalno ljuštenje stanica. Na osnovi stanične gustoće, akutni endometritis bio je dokazan u 68 (31,33 %) uzoraka, kronični u 23 (10,60 %), a subakutni u 35 (16,13 %) uzoraka. Zaključno, citologija endometrija pokazala se primjenjljivom i pouzdanom metodom u dijagnostici odnosno razlikovanju akutnog od kroničnog endometritisa

Spontaneous Rupture of the Ascending Thoracic Aorta in Young Man

Spontaneous rupture of the aorta without previous history of trauma, hypertension or apparent aortic pathology is rare. Delayed or nonoperative repair of this condition is usually lethal. We report spontaneous rupture of the ascending thoracic aorta in young man. A 20-year-old male who had complained of sudden onset of severe chest pain and dispnea was admitted to our hospital. Initially, acute type A closing aortic dissection was suspected but computed tomography (CT) showed no intimal flap, false lumen or aortic aneurysm. [Med-Science 2015; 4(1.000): 1809-17

Isolated coronary artery bypass surgery in patients with mild to moderate ischemic mitral regurgitation: Early results

The optimal management of moderate ischemic mitral regurgitation (MR) remains controversial. Some surgeons advocate coronary artery bypass alone, while others suggest concomitant mitral valve annuloplasty. We aimed to evaluate the early results of isolated coronary artery bypass operation on the cases with mild-to-moderate ischemic MR. Between May 2010 and May 2011, 59 patients (64% male, mean age: 50.5 years) with a preoperative diagnosis of mild-to-moderate ischemic MR underwent a coronary bypass operation. Patients evaluated with preoperative and postoperative (in twelve-month period with an average of five months) transthoracic echocardiogram (TTE). Postoperative mortality was not observed in study group. The preoperative functional capacity of the patients as well as the variables of mild MR and moderate MR showed a statistically significant difference in a positive way when compared with the postoperative functional capacity and MR variables. Postoperative TTE evaluation revealed that only 2 cases have severe MR (3,4%) also 62,7 % of patients have mild and 33.9% of patients have moderate MR. While there was a significant difference in a positive way between the preoperative and postoperative period in terms of left atrial diameter, no significant difference was found for the variables of ejection fraction and pulmonary artery pressure. Among the patients whom undergoing coronary bypass surgery, if there is mild or moderate MR revealed with the TTE prior to the operation, performing only coronary bypass operation will be adequate, and our early results in this matter are satisfactory. But, if severe MR revealed with TTE, performance of mitral valve repair or replacement should be evaluated additional to coronary bypass operation. [Med-Science 2018; 7(1.000): 114-117

The Effect of Selective Endothelin Receptor a Antagonism by Bq-123 on Myocardial Ischemia-Reperfusion Induced Apoptotic Cell Death

The objective of the present study was to investigate the possible impact of specific endothelin-A (ETA) receptor blockage by BQ-123 on myocardial ischemia-reperfusion (MI/R) induced apoptosis in rats. To produce MI/R, a branch of the descending left coronary artery was occluded for 30 min followed by 2 h reperfusion. Thirty-two rats were randomly assigned to four groups equally: (1) sham-operated group, (2) MI/R group, (3) MI/R+BQ-123-treated group, and (4) MI/R+ET-1+BQ-123-treated group. TUNEL staining, caspase-3 and caspase-9 activities were determined immunohistologically. MI/R group revealed extensive TUNEL positive cardiomyocytes especially in the free wall of the left ventricule, interventicular septum, and apex zone. Intensity of TUNEL-positive cardiomyocytes reduced as a result of BQ-123 treatment compared to the sham group in the same sections. Result of the caspase activity was found to correlate with TUNEL evaluation. BQ-123 administrations to MI/R group with or without ET-1 caused significant decrease both in lipid peroxidation and nitric oxide (NO) generation. Also, BQ-123 leads to augmentation of superoxide dismutase, catalase and glutathione contents. We propose that selective ETA antagonism by BQ-123 has a worthwhile effect on apoptotic cell death following MI/R, and that scavenging of free radicals by selective ETA antagonist is part of this beneficial effect. [Med-Science 2012; 1(4.000): 254-70

An investigation of tinnitus, noise sensitivity and anxiety levels in liver transplantation patients in the early and late periods: A cross-sectional study

This study aims to evaluate the perception of anxiety, tinnitus, and noise sensitivity in liver transplant patients according to early and late periods following transplantation. The study included 76 patients with liver transplantation. They were divided into two groups according to the duration of time after transplantation: early (1-3 years) and late (5 years or more). A demographic data form, the Tinnitus Handicap Inventory (THI), Weinstein's Noise Sensitivity Scale (WNSS), and the Beck Anxiety Inventory (BAI) were administered and used for data collection. There was a statistically significant difference between the early and late-period groups in terms of WNSS and THI scores (p0.05). Noise sensitivity and tinnitus perception of the late-period group were statistically higher than those of the early-period group (p [Med-Science 2023; 12(3.000): 896-901

Successful Mitral Valve Replacement in Patient with Severe Hemolytic Anemia due to Tight Mitral Stenosis

A 43 year-old woman complained of palpitation and shortness of breath admitted to our hospital. Transthoracic echocardiography revealed severe mitral stenosis and moderate mitral regurgitation. In routine blood tests hemoglobin and lactate dehydrogenase levels were 7.6 g/dL, 520 IU/L respectively. Coombs test was negative. After studying the other intrinsic or extrinsic causes of hemolytic anemia patients anemia was diagnosed as intravascular hemolytic anemia due to tight mitral stenosis. Therefore, mitral valve replacement planned and performed. Hemolysis was resolved after the mitral valve replacement. In conclusion, we report a case of hemolyt ic anemia due to mitral stenosis resolved by mechanical mitral valve replacement. [Med-Science 2016; 5(2.000): 738-41

Effects of rivaroxaban on myocardial ischemia-reperfusion injury in rats

Myocardial infarction and further ischemia-reperfusion injury is a life-threatening conditions in humans. In this study, the effects of rivaroxaban, an anticoagulant agent, were aimed to be studied in a myocardial ischemia-reperfusion (I/R) injury model in rats. Male Wistar-albino rats were allocated into three groups; Rivaroxaban (n=15), control (n=15) and sham (n=10). Myocardial ischemia (30 minutes) and then reperfusion (120 minutes) were surgically performed in the rivaroxaban given (3mg/kg/day by gavage for 10 days before surgical procedures) and the control groups. Electrocardiography changes, blood pressure and heart rate were recorded before ischemia, and during the periods of ischemia and the reperfusion. Hemodynamic and blood parameters were recorded. Necrotic tissue in the myocardium was determined by the triphenyl tetrazolium chloride dye method. The extent of myocardial necrosis and risk area was calculated using a computer-assisted image program. In the rivaroxaban administered group, the size of necrotic area in the myocardium decreased significantly, however, mean heart rate and mean arterial blood pressure did not change. K+ and CK levels in serum, which are indicative of tissue necrosis, were significantly lower in the rivaroxaban group compared to the control group (p [Med-Science 2022; 11(4.000): 1456-60

The Amputation Endicated Extremity Can Be Recovered by Multidisciplinary Treatment: A Case Report and Review of Literature [Multidisipliner Yaklasimla Amputasyon Endikasyonu Olan Ekstremite Kurtarilabilir: Olgu Sunumu ve Literatur Derlemesi]

With the development of microsurgical techniques and successfull multidisciplinary approach; many injuries that requires amputation can be treated successfully by extremity preventing surgery. We present a case that admitted to our clinic with open fracture and although had amputation endication, treated with extremity reconstruction surgery. [Med-Science 2015; 4(2.000): 2281-8