Novel Physical Therapy Protocol Targeting Insertional Achilles Tendinopathy Improves Patient Reported Outcomes that Persist For 1 Year

Category: Sports Introduction/Purpose: Insertional Achilles Tendinopathy (IAT) affects 5% of the general population and up to 20% of the athletic population. Despite trials of non-surgical management such as physical therapy and heels lifts, more than 50% of patients ultimately pursue surgery. One hypothesis regarding the development of IAT pain and stiffness is that ankle dorsiflexion and associated calcaneal impingement causes transverse compression of the tendon insertion, inducing metaplastic changes within the Achilles tendon, and bursa, contributing to inflammation. Thus the aim of the current study is to examine the effect of a home exercise program designed to minimize compression of insertional tissues for patients with IAT on patient reported outcomes (PRO) measures at 3 months and one year. Methods: Thirty-five patients with IAT were enrolled in the study from May 2014 until June 2015 as two separate cohorts (21 and 14 patients, respectively) of whom 26 completed the study (mean age: 56.7 + 10.1 years, BMI: 29.5 + 6.0 kg/m2, 58% women). One patient elected for surgery prior to completing the physical therapy protocol. Physical therapy exercises were progressive eccentric loading of the Achilles tendon and seated isometric plantar flexion that were performed 4 times a week for 3 months. The Victorian Institute of Sport Assessment – Achilles (VISA-A), the Foot and Ankle Ability Measure (FAAM) and the SF-36 questionnaires were completed at baseline and at the completion of the 3-month physical therapy protocol. Six of the 14 patients in the second cohort returned for a 1 year follow up visit; four patients were lost to follow up and 4 had undergone surgical intervention prior to 1-year follow up. Results: Completion of the 3 month protocol resulted in statistically significant improvements in VISA-A, FAAM ADL and sports scores as well as multiple subcategories of the SF-36 (physical function, role limiting physical function, energy/vitality, social functioning and general pain). Twenty-two of the 26 patients (~85%) that completed the study had clinically significant, greater than MCID, improvements in their VISA-A and/or FAAM scores. In the second cohort, all six patients that returned for a one year follow up assessment maintained their improved VISA-A and FAAM scores observed at the end of the initial physical therapy protocol. Of the four patients that underwent surgical intervention prior to follow up, two did not demonstrate improvement in any of their outcomes following the initial study period. Conclusion: The results of the present study suggest that a physical therapy home exercise program utilizing eccentric and isometric Achilles exercises may result in a greater improvement in functional outcomes compared to other exercise programs that do not progressively increase both ankle dorsiflexion and Achilles tendon loading. Furthermore, improvements in pain and function result in increased energy and social wellbeing. Finally, symptomatic improvement that occurs after 3 months is likely to persist for at least one year following initial treatment

Novel Physical Therapy Protocol Results in Increased Compressive Strain and Improved Outcomes in Insertional Achilles Tendinopathy

Category: Ankle, Hindfoot, Sports Introduction/Purpose: Insertional Achilles Tendinopathy (IAT) affects 5% of the general population and up to 20% of the athletic population. Despite trials of non-surgical management, over 50% of patients ultimately pursue surgery. Previously in healthy controls it was demonstrated that ankle dorsiflexion tasks increase transverse compressive strain (force perpendicular to the tendon fibers) most in the deep region of the tendon insertion, where IAT is often most severe. Thus the purpose of this study was to utilize a novel physical therapy protocol that combines isometric and eccentric exercises in order to increase transverse compressive strain and decrease axial tensile strain (force parallel to tendon fibers) in patients with IAT and to determine whether this corresponds with improved patient outcome scores. Methods: Forty-two patients with IAT were enrolled in the study from May 2014 to June 2016, of which twenty-seven patients (mean age: 56.7 + 9.9 years, BMI: 29.6 + 5.9, 56% women) completed the study. A subset (n=15, mean age 58.9 + 8.6 years, BMI: 30.0 + 4.0, 47% women) underwent ultrasound elastography to determine transverse compressive and axial tensile strain in the Achilles tendon during dorsiflexion tasks. Patients were then placed on a physical therapy protocol that focused on progressive loading of the Achilles tendon while avoiding ankle dorsiflexion. Seated isometric plantar flexion, bilateral eccentric heel lowering, and single limb heel lowering exercises were utilized. Questionnaires validated for use in Achilles tendinopathy, the Victorian Institute of Sport Assessment – Achilles (VISA-A) and the Foot and Ankle Ability Measure (FAAM), were completed at the beginning and at the completion of the study. Results: Twenty-three of 27 subjects that completed the study, had clinically significant improvements in their VISA-A (mean change 19.3) or FAAM ADL and sports scores (mean change 16.2 and 22.6, respectively). Ultrasound elastography revealed that the deep region of the Achilles tendon experienced more transverse compressive strain and less axial tensile strain compared to the superficial portion of the tendon when standing. Completion of the physical therapy program resulted in increased transverse compressive strain in the superficial Achilles tendon compared to the pre-therapy value when standing (mean change 52%, p=0.043). Moreover, there was a decrease in axial tensile strain within the deep portion of the tendon in response to physical therapy (mean change 53% p=0.0434). Conclusion: Treatment of IAT patients with a physical therapy protocol utilizing a combination of isometric and eccentric exercises results in improved outcomes, as measured by VISA-A and FAAM questionnaires. Furthermore, ultrasound elastography suggests that while the physical therapy protocol increases the transverse compressive strain in the superficial portion of the Achilles tendon, it results in decreased axial tensile strain in the deep portion of the tendon. Therefore, it is likely that the combination of these two exercise modalities result in the improved clinical outcomes observed in our patients with IAT after undergoing this physical therapy protocol

Clinical Outcomes Following Percutaneous Ankle Fusion With Bone Graft Substitute

Background: Percutaneous ankle fusion is an emerging technique with minimal published outcome data. The goal of the present study is to retrospectively review clinical and radiographic outcomes following percutaneous ankle fusion and provide technique tips to perform percutaneous ankle fusion. Methods: Patients >18 years of age, treated by a single surgeon, from February 2018 to June 2021, who underwent primary isolated percutaneous ankle fusion supplemented with platelet-derived growth factor B (rhPDGF-BB) and beta-tricalcium phosphate, with at least 1-year follow-up were included. Surgical technique consisted of percutaneous ankle preparation followed by fixation with 3 headless compression screws. Pre- and postoperative visual analog scale (VAS) and Foot Function Index (FFI) were compared using paired t tests. Fusion was assessed radiographically by the surgeon on postoperative radiographs and computed tomography (CT) at 3 months postoperatively. Results: Twenty-seven consecutive adult patients were included in the study. Mean follow-up was 21 months. Mean age was 59.8 years. Mean preoperative and postoperative VAS scores were 7.4 and 0.2, respectively ( P  < .01). Mean preoperative FFI pain domain, disability domain, activity restriction domain, and total score were 20.9, 16.7, 18.5, and 56.4, respectively. Mean postoperative FFI pain domain, disability domain, activity restriction domain, and total score were 4.3, 4.7, 6.7, and 15.8, respectively ( P  < .01). Fusion was achieved in 26 of 27 patients (96.3%) at 3 months. Four patients (14.8%) had complications. Conclusion: We found in this cohort with surgery performed by a surgeon highly experienced in minimally invasive surgery that percutaneous ankle fusion augmented with a bone graft supplement achieved a high rate of fusion (96.3%) and a significant improvement in pain and function postoperatively while associated with minimal complications. Level of Evidence: Level IV, case series

Spring Ligament Tear Decreases the Ankle and Talonavicular Joint Reaction Forces

Category: Other Introduction/Purpose: Spring ligament tear is often noted in advanced stages of the adult acquired flatfoot deformity (AAFD). Previous anatomic studies demonstrated that the spring and deltoid ligaments are not separate structure, but form a confluent ligament in which the tibiocalcaneonavicular ligament (TCNL) comprises the largest component. A biomechanical study which utilized stage IIB AAFD model demonstrated inferior result of the anatomic spring ligament reconstruction compared to the tibionavicular ligament reconstruction. Therefore, the TCNL reconstruction has been proposed for effective restoration of the ankle and talonavicular joints stability in AAFD with a large spring ligament tear. We aimed to investigate if spring ligament tear of greater than 1.5 cm decreases the ankle and talonavicular joint reaction forces (JRF), and if they could be restored by the TCNL reconstruction. Methods: Ten fresh-frozen human cadaveric lower legs were obtained and disarticulated at the knee joint. Steinmann pins were percutaneously placed across the distal tibia, center of the talus and navicular while preserving adjacent soft tissues. A distraction force was applied across the ankle and talonavicular joints to determine the baseline force displacement curve to generate a best- fit polynomial equation to determine normal JRF. A spring ligament injury model was created by releasing the medial capsuloligamentous complex of the talonavicular joint and extending the resection 1.5 cm proximally. The TCNL reconstruction was performed with a forked semitendinosus allograft. The folded portion of the graft was fixed to the medial malleolar inter- colliculus. One limb of the separated part of the allograft was fixed to the navicular tuberosity and the other limb was fixed to the calcaneus below the sustentaculum tali. The resultant JRFs across the tibiotalar and talonavicular joints were measured after each step. Results: The mean baseline JRFs of the ankle and talonavicular joints were 8.36 N +/- 1.8 N and 3.01 N +/- 0.9 N, respectively. The spring ligament tear resulted in 29% decrease in tibiotalar JRF (5.97 N +/- 1.1 N, p0.05). Although the tibionavicular ligament reconstruction partially restored JRFs of the tibiotalar (7.83 +/- 2.4 N, p> 0.05) and talonavicular joints (4.08 N +/- 1.8 N, p> 0.05), they were not statistically significant. Addition of the tibiocalcaneal ligament reconstruction resulted in significantly increased JRFs of the tibiotalar (9.17 +/- 3.93 N, p> 0.05) and talonavicular joints (4.35 +/- 2.04 N, p> 0.05) compared to the spring ligament injury model. Conclusion: This is the first biomechanical study to demonstrate that a large size (>1.5 cm) spring ligament tear results in decreased JRF of the ankle joint. The decreased ankle and talonavicular JRFs were effectively restored by the novel TCNL reconstruction. This technique utilizes a forked allograft with two limbs for the tibionavicular and tibiocalcaneal ligaments reconstructions. Advanced AAFD with a large size spring ligament tear may have medial ankle instability that should not be overlooked. The novel TCNL reconstruction should be considered to prevent progression of valgus deformity. The biomechanical and clinical efficacies of the TCNL reconstruction warrant further investigation

Pain Assessment in Foot and Ankle Patients

Category: Other Introduction/Purpose: The ability to accurately quantify a patient’s pain pre-operatively is advantageous in the preparation of post-operative expectations and pain management. The Numeric Pain Rating Scale (NPRS) is a popular method to identify patient pain level. Other patient reported outcomes are being collected, such as the Patient Reported Outcomes Measurement Information System (PROMIS) and has been suggested to be more accurate in measuring pain as well as physical function. The aim of this study was to 1) determine whether NPRS or PROMIS Pain Interference (PI) demonstrates a stronger association with physical function as determined by PROMIS Physical Function (PF) and 2) to determine which method better predicts post-surgical pain in a population of elective surgical foot and ankle patients. Methods: Prospective PROMIS PF, PI and NPRS (0-10) data was obtained for common foot and ankle elective surgical procedures (CPT codes 27698, 27870, 28285, 28289, 28300, 28705, 28730, 28750) from a multi-surgeon foot and ankle clinic between February 2015 until November 2017. Pearson correlation coefficients were used to determine the relationship between NPRS (0-10) and PROMIS domains (PI, PF) pre and post-operatively. Correlations were considered high (> 0.7), high moderate (0.6-0.69), moderate (0.4-0.6) or weak ( 6 month follow up were evaluated (74% women, mean age 54+/- SD, mean follow-up 14.4 months, range 6-34 months). Pearson correlation evaluation of NPRS and PI revealed a moderate correlation in the pre- and postoperative setting. There was a high moderate negative correlation between PI and PF t-scores pre and postoperatively suggesting more pain and less function. However, the negative correlation between NPRS and PF pre- and postoperatively was weak indicating a poor relationship between NPRS pain assessment and function. There was a moderate correlation between pre- and postoperative scores in all domains of PROMIS while the correlation between pre- and postoperative NPRS scores was weak. Conclusion: In a population of elective surgical foot and ankle patients, the use of both NPRS and PROMIS can be utilized to assess pain level, however the PROMIS PI domain demonstrated a stronger relationship with PROMIS PF than NPRS. Furthermore, only the PROMIS domains demonstrated at least a moderate correlation between pre- and post-operative scores. PROMIS PI provides superior assessment of pre- and post-operative physical function and prediction of post-operative pain. PROMIS PI can be used to gauge a patient’s pre-operative level of pain and function and aid the surgeon in guiding post-operative patient expectations and pain management

A Novel Method for Measurement of Ankle Joint Reaction Force and Response to Syndesmotic Injury

Category: Ankle. Introduction/Purpose: Increasing evidence has suggested that alterations in joint mechanics results in articular pathology. Previous studies demonstrated noninvasive measurements of joint reactive forces (JRF) can be performed reliably without destruction of the peri-articular soft tissue in medium and small size joints of the upper extremity. This study presents a novel, noninvasive measurement of the JRF to investigate the normal and the effects of a syndesmotic injury. The JRF of the tibiotalar joint was also evaluated following anatomic reduction with fixation and malreduction of the syndesmosis. Methods: Eight fresh-frozen human cadaveric lower extremity limbs were obtained disarticulated above the knee. A distraction force was applied across the tibio-talar joint to determine the baseline (normal) ankle force displacement curve. Next, a syndesmotic injury was created by releasing the interosseous syndesmotic ligaments, the transverse tibiofibular ligament and the anterior and posterior tibiofibular ligaments. Prior to sectioning, two drill holes were placed across the joint and tapped to ensure anatomic reduction. JRF were measured using a quadricortical technique with a single or double screw configuration. The syndesmosis was malreduced by anteriorly displacing the fibula 5 mm. After each step, the resultant JRFs were determined using a distraction force across the tibiotalar joint. Results: Force displacement curves obtained from multiple measurements from each specimen with a mean ankle JRF of 31.4 + 2.6 N. Syndesmotic injury resulted in a 35% decrease in tibiotalar JRF (20.3 + 3.0 N, p=0.002). Fixation of the injury using one syndesmotic screw resulted in significant increase in JRF compared to injury JRF (28.7 + 1.4 N, p=0.02). Syndesmotic fixation with 2 screws also demonstrated a trend towards restoration of tibiotalar JRF (28.3 + 2.2 N, p=0.06). There was no statistical difference between fixation of one versus two syndesmotic screws. The JRF for the malreduced syndesmosis was 31.5 + 1.8 N (p=0.03,) resulting in increased forces approaching the baseline JRF. Conclusion: This study demonstrates a non-destructive model by which to measure joint reactive forces (JRF) across the tibiotalar joint and that these forces are diminished as a result of a syndesmotic injury, suggesting joint instability. Surgical stabilization with either 1 or 2 screws creates JRF that are similar to the normal JRF. Even with a malreduced syndesmosis, there appeared to be a JRF similar to baseline tibiotalar joint forces. However malreduction of the syndesmosis may alter the joint dynamics of the ankle in ways that were not measured in this study