An unusual case of septate uterus with double cervix and longitudinal vaginal septumâwith pregnancy

Various theories and classification systems have been proposed from time to time, to understand the embryology of the female genital system. Even then at times we come across something different, something new, which again questions our understanding of this subject matter and the theories which are most accepted worldwide. Mullerian anomalies result from the improper development and fusion of the embryological mullerian ducts. It is generally considered to occur in less than 5% of women. Here we present a rare and interesting case of a young female having septate uterus with double cervix and a longitudinal vaginal septum with pregnancy. Keywords: Embryology, Septate uterus, Double cervix, Longitudinal vaginal septu

Comparison of effect of simvastatin and metformin monotherapy on lipid profile and testosterone levels in polycystic ovary syndrome

Background: Polycystic ovary syndrome has consequences like insulin resistance, hyperandrogenism and dyslipidemia. Metformin is commonly used for treatment of this disorder and its effects on various biochemical parameters are compared with a cardioprotective drug simvastatin. Method: Fifty patients of polycystic ovary syndrome were divided into two groups depending on metformin or simvastatin administration for a period of 6 months. Levels of serun glucose, insulin, and testosterone and lipid profile were estimated before and after treatment and compared statistically for both the groups.Results: Metformin and simvastatin reduced levels of insulin and testosterone and improved lipid profile in patients of polycystic ovary disease. The effects of two groups were found to be statistically comparable. Conclusion: Efficacy of simvastatin is comparable to metformin for treatment of polycystic ovary syndrome, though more studies are required to support this view