16 research outputs found
Π‘ΠΎΠ²Π΅ΡΡΠ΅Π½ΡΡΠ²ΠΎΠ²Π°Π½ΠΈΠ΅ ΡΠΈΡΡΠ΅ΠΌΡ ΠΌΠΎΡΠΈΠ²Π°ΡΠΈΠΈ ΠΈ ΡΡΠΈΠΌΡΠ»ΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΡΡΡΠ΄Π° ΡΠ°Π±ΠΎΡΠ½ΠΈΠΊΠΎΠ² Π½Π° ΠΏΡΠΈΠΌΠ΅ΡΠ΅ ΠΠΠ "Π ΠΎΡΡΠ΅Π»Π΅ΠΊΠΎΠΌ"
ΠΠ±ΡΠ΅ΠΊΡ ΠΠΠ - ΡΠΈΡΡΠ΅ΠΌΠ° ΠΌΠΎΡΠΈΠ²Π°ΡΠΈΠΈ ΠΈ ΡΡΠΈΠΌΡΠ»ΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΏΠ΅ΡΡΠΎΠ½Π°Π»Π°. Π¦Π΅Π»Ρ ΠΠΠ β ΠΈΠ·ΡΡΠ΅Π½ΠΈΠ΅ ΠΎΡΠΎΠ±Π΅Π½Π½ΠΎΡΡΠ΅ΠΉ ΡΠΈΡΡΠ΅ΠΌΡ ΠΌΠΎΡΠΈΠ²Π°ΡΠΈΠΈ ΠΈ ΡΡΠΈΠΌΡΠ»ΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΡΡΡΠ΄Π° ΡΠ°Π±ΠΎΡΠ½ΠΈΠΊΠΎΠ² ΠΠΠ "Π ΠΎΡΡΠ΅Π»Π΅ΠΊΠΎΠΌ" ,Π°Π½Π°Π»ΠΈΠ· ΠΏΡΠΈΠΌΠ΅Π½ΡΠ΅ΠΌΡΡ
ΠΌΠ΅ΡΠΎΠ΄ΠΎΠ² ΠΌΠΎΡΠΈΠ²Π°ΡΠΈΠΈ ΠΈ ΡΡΠΈΠΌΡΠ»ΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΈ ΡΠ°Π·ΡΠ°Π±ΠΎΡΠΊΠ° ΡΠ΅ΠΊΠΎΠΌΠ΅Π½Π΄Π°ΡΠΈΠΉ. Π ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠ΅ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ Π±ΡΠ» ΡΠ°Π·ΡΠ°Π±ΠΎΡΠ°Π½ ΡΡΠ΄ ΠΌΠ΅ΡΠΎΠΏΡΠΈΡΡΠΈΠΉ ΠΏΠΎ ΡΠΎΠ²Π΅ΡΡΠ΅Π½ΡΡΠ²ΠΎΠ²Π°Π½ΠΈΡ ΡΠΈΡΡΠ΅ΠΌΡ ΠΌΠΎΡΠΈΠ²Π°ΡΠΈΠΈ ΠΈ ΡΡΠΈΠΌΡΠ»ΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΏΠ΅ΡΡΠΎΠ½Π°Π»ΠΎΠΌ.Object of WKR is a system of motivation and incentives for staff. The purpose of WKR is to study the features of the system of motivation and motivation of the work of PAO "Rostelecom" employees, analyze the methods of motivation and incentives used and develop recommendations. As a result of the research, a number of measures were developed to improve the system of motivation and incentives for staff
Nuclear factor-ΞΊB regulates the expression of multiple genes encoding liver transport proteins
Sedimentation rates of fine aerosols in acoustic and electric field
ΠΠΊΡΡΠ°Π»ΡΠ½ΠΎΡΡΡ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ ΡΠ²ΡΠ·Π°Π½Π° Ρ ΠΏΠΎΠΈΡΠΊΠΎΠΌ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΡΡ
ΡΠΏΠΎΡΠΎΠ±ΠΎΠ² ΠΎΡΠ°ΠΆΠ΄Π΅Π½ΠΈΡ ΠΌΠ΅Π»ΠΊΠΎΠ΄ΠΈΡΠΏΠ΅ΡΡΠ½ΡΡ
Π°ΡΡΠΎΠ·ΠΎΠ»Π΅ΠΉ Ρ ΡΠ΅Π»ΡΡ ΠΎΡΠΈΡΡΠΊΠΈ ΠΏΡΠΎΠΈΠ·Π²ΠΎΠ΄ΡΡΠ²Π΅Π½Π½ΡΡ
ΠΏΠΎΠΌΠ΅ΡΠ΅Π½ΠΈΡ ΠΎΡ ΠΏΡΠ»ΠΈ ΠΈ Π΄ΡΠΌΠ°. Π Π°Π·Π²ΠΈΡΠΈΠ΅ ΠΌΠ΅ΡΠΎΠ΄ΠΎΠ² ΠΎΠ±Π΅ΡΠΏΠ΅ΡΠ΅Π½ΠΈΡ ΡΠΈΡΡΠΎΡΡ Π²ΠΎΠ·Π΄ΡΡΠ½ΠΎΠΉ ΡΡΠ΅Π΄Ρ Π² ΠΏΡΠΎΠΈΠ·Π²ΠΎΠ΄ΡΡΠ²Π΅Π½Π½ΡΡ
ΠΏΠΎΠΌΠ΅ΡΠ΅Π½ΠΈΡΡ
ΠΎΡΠΎΠ±Π΅Π½Π½ΠΎ Π°ΠΊΡΡΠ°Π»ΡΠ½ΠΎ Π² ΡΠ²ΡΠ·ΠΈ Ρ ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ΠΌ Π½Π°Π½ΠΎΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΠΉ, Π° ΡΠ°ΠΊΠΆΠ΅ Ρ
ΠΈΠΌΠΈΡΠ΅ΡΠΊΠΈΡ
ΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΠΉ, ΡΠ²ΡΠ·Π°Π½Π½ΡΡ
Ρ Π²ΠΎΠ·ΠΌΠΎΠΆΠ½ΡΠΌΠΈ Π²ΡΠ±ΡΠΎΡΠ°ΠΌΠΈ Π²ΡΠ΅Π΄Π½ΠΎΠΉ ΠΈ ΠΎΠΏΠ°ΡΠ½ΠΎΠΉ ΠΏΡΠ»ΠΈ. Π¦Π΅Π»Ρ ΡΠ°Π±ΠΎΡΡ: ΠΏΠΎΠΈΡΠΊ ΠΎΠΏΡΠΈΠΌΠ°Π»ΡΠ½ΡΡ
ΡΠΏΠΎΡΠΎΠ±ΠΎΠ² ΠΎΡΠ°ΠΆΠ΄Π΅Π½ΠΈΡ ΠΌΠ΅Π»ΠΊΠΎΠ΄ΠΈΡΠΏΠ΅ΡΡΠ½ΡΡ
Π°ΡΡΠΎΠ·ΠΎΠ»Π΅ΠΉ ΠΏΡΠΈ ΡΡΠ°Π²Π½Π΅Π½ΠΈΠΈ ΡΠ»Π΅ΠΊΡΡΠΎΡΡΠ°ΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΈ ΡΠ»ΡΡΡΠ°Π·Π²ΡΠΊΠΎΠ²ΠΎΠ³ΠΎ ΡΠΏΠΎΡΠΎΠ±ΠΎΠ² ΠΎΡΠ°ΠΆΠ΄Π΅Π½ΠΈΠ΅ ΡΠ°ΡΡΠΈΡ. ΠΠ±ΡΠ΅ΠΊΡΡ: ΠΌΠ΅Π»ΠΊΠΎΠ΄ΠΈΡΠΏΠ΅ΡΡΠ½ΡΠ΅ Π°ΡΡΠΎΠ·ΠΎΠ»ΠΈ ΠΈ ΡΠΏΠΎΡΠΎΠ±Ρ ΠΈΡ
ΠΎΡΠ°ΠΆΠ΄Π΅Π½ΠΈΡ. ΠΠ΅ΡΠΎΠ΄Ρ: ΠΌΠ°ΡΠ΅ΠΌΠ°ΡΠΈΡΠ΅ΡΠΊΠΎΠ΅ ΠΌΠΎΠ΄Π΅Π»ΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅, ΠΎΠΏΡΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΠΌΠ΅ΡΠΎΠ΄Ρ ΠΈΠ·ΠΌΠ΅ΡΠ΅Π½ΠΈΡ ΡΡΠ½ΠΊΡΠΈΠΈ ΡΠ°ΡΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΡ ΡΠ°ΡΡΠΈΡ ΠΏΠΎ ΡΠ°Π·ΠΌΠ΅ΡΠ°ΠΌ ΠΈ ΠΊΠΎΠ½ΡΠ΅Π½ΡΡΠ°ΡΠΈΠΈ ΡΠ°ΡΡΠΈΡ Π°ΡΡΠΎΠ·ΠΎΠ»Ρ Ρ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΠ΅ΠΌ Π»Π°Π·Π΅ΡΠ½ΠΎΠ³ΠΎ ΠΈΠ·ΠΌΠ΅ΡΠΈΡΠ΅Π»ΡΠ½ΠΎΠ³ΠΎ ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΠ° ΠΠΠ-2Π ΠΈ Π°Π½Π°Π»ΠΈΠ·Π°ΡΠΎΡΠ° Malvern Spraytec. Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ. ΠΡΠΎΠ²Π΅Π΄Π΅Π½ ΡΠ΅ΠΎΡΠ΅ΡΠΈΡΠ΅ΡΠΊΠΈΠΉ Π°Π½Π°Π»ΠΈΠ· ΡΠΊΠΎΡΠΎΡΡΠ΅ΠΉ ΠΎΡΠ°ΠΆΠ΄Π΅Π½ΠΈΡ ΡΠ°ΡΡΠΈΡ ΠΌΠ΅Π»ΠΊΠΎΠ΄ΠΈΡΠΏΠ΅ΡΡΠ½ΡΡ
Π°ΡΡΠΎΠ·ΠΎΠ»Π΅ΠΉ (Π΄ΠΈΠ°ΠΌΠ΅ΡΡ 1-20 ΠΌΠΊΠΌ) Π² ΠΏΡΠΈΡΡΡΡΡΠ²ΠΈΠΈ Π°ΠΊΡΡΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ, ΡΠ»Π΅ΠΊΡΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΏΠΎΠ»Ρ Ρ ΡΡΠ΅ΡΠΎΠΌ Π΄ΡΠ΅ΠΉΡΠ° Π² ΡΠ»Π΅ΠΊΡΡΠΈΡΠ΅ΡΠΊΠΎΠΌ ΠΏΠΎΠ»Π΅, ΡΠ»ΡΡΡΠ°Π·Π²ΡΠΊΠΎΠ²ΠΎΠΉ ΠΊΠΎΠ°Π³ΡΠ»ΡΡΠΈΠΈ ΠΈ Π°ΠΊΡΡΡΠΈΡΠ΅ΡΠΊΠΈΡ
ΡΠ΅ΡΠ΅Π½ΠΈΠΉ (Β«Π·Π²ΡΠΊΠΎΠ²ΠΎΠ³ΠΎ Π²Π΅ΡΡΠ°Β»). ΠΠΏΡΠ΅Π΄Π΅Π»Π΅Π½Ρ Π²Π΅Π΄ΡΡΠΈΠ΅ ΠΌΠ΅Ρ
Π°Π½ΠΈΠ·ΠΌΡ ΠΎΡΠ°ΠΆΠ΄Π΅Π½ΠΈΡ ΡΠ°ΡΡΠΈΡ Π² Π·Π°Π²ΠΈΡΠΈΠΌΠΎΡΡΠΈ ΠΎΡ ΠΈΡ
ΡΠ°Π·ΠΌΠ΅ΡΠ°, ΡΡΠΎ ΠΏΠΎΠ·Π²ΠΎΠ»ΡΠ΅Ρ ΠΏΡΠ΅Π΄Π»ΠΎΠΆΠΈΡΡ ΠΎΠΏΡΠΈΠΌΠ°Π»ΡΠ½ΡΠ΅ ΡΠΏΠΎΡΠΎΠ±Ρ ΠΎΡΠ°ΠΆΠ΄Π΅Π½ΠΈΡ ΠΌΠ΅Π»ΠΊΠΎΠ΄ΠΈΡΠΏΠ΅ΡΡΠ½ΡΡ
Π°ΡΡΠΎΠ·ΠΎΠ»Π΅ΠΉ Π² ΠΊΠ°ΠΆΠ΄ΠΎΠΌ Π΄ΠΈΠ°ΠΏΠ°Π·ΠΎΠ½Π΅ ΡΠ°Π·ΠΌΠ΅ΡΠΎΠ² ΡΠ°ΡΡΠΈΡ. ΠΠ°ΡΠ΅ΠΌΠ°ΡΠΈΡΠ΅ΡΠΊΠ°Ρ ΠΌΠΎΠ΄Π΅Π»Ρ Π°ΠΊΡΡΡΠΈΡΠ΅ΡΠΊΠΎΠΉ ΠΊΠΎΠ°Π³ΡΠ»ΡΡΠΈΠΈ ΠΎΡΠ½ΠΎΠ²Π°Π½Π° Π½Π° ΠΈΠ½ΡΠ΅Π³ΡΠ°Π»ΡΠ½ΠΎΠΉ ΡΠΎΡΠΌΠ΅ ΡΡΠ°Π²Π½Π΅Π½ΠΈΡ Π‘ΠΌΠΎΠ»ΡΡ
ΠΎΠ²ΡΠΊΠΎΠ³ΠΎ. ΠΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½Ρ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΡ ΡΠΊΡΠΏΠ΅ΡΠΈΠΌΠ΅Π½ΡΠ°Π»ΡΠ½ΠΎΠ³ΠΎ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ ΠΎΡΠ°ΠΆΠ΄Π΅Π½ΠΈΡ ΡΠ°ΡΡΠΈΡ ΠΌΠΎΠ΄Π΅Π»ΡΠ½ΠΎΠ³ΠΎ Π°ΡΡΠΎΠ·ΠΎΠ»Ρ (NaCl) Ρ Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠ½ΡΠΌ Π΄ΠΈΠ°ΠΌΠ΅ΡΡΠΎΠΌ ΡΠ°ΡΡΠΈΡ ΠΎΠΊΠΎΠ»ΠΎ 6 ΠΌΠΊΠΌ Ρ ΠΏΠΎΠΌΠΎΡΡΡ ΡΠ»ΡΡΡΠ°Π·Π²ΡΠΊΠ° ΠΈ Ρ ΠΏΠΎΠΌΠΎΡΡΡ ΡΠ»Π΅ΠΊΡΡΠΎΠΎΡΠ°ΠΆΠ΄Π°ΡΡΠ΅Π³ΠΎ ΡΡΡΡΠΎΠΉΡΡΠ²Π°. Π£ΡΡΠ°Π½ΠΎΠ²Π»Π΅Π½ΠΎ, ΡΡΠΎ ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ Π΄Π°Π½Π½ΡΡ
ΡΠΏΠΎΡΠΎΠ±ΠΎΠ² ΠΎΡΠ°ΠΆΠ΄Π΅Π½ΠΈΡ ΡΡΡΠ΅ΡΡΠ²Π΅Π½Π½ΠΎ ΡΡΠΊΠΎΡΡΠ΅Ρ ΡΠ΅Π΄ΠΈΠΌΠ΅Π½ΡΠ°ΡΠΈΡ ΠΌΠΎΠ΄Π΅Π»ΡΠ½ΠΎΠ³ΠΎ Π°ΡΡΠΎΠ·ΠΎΠ»Ρ, ΡΡΠΎ ΡΠΎΠΎΡΠ²Π΅ΡΡΡΠ²ΡΠ΅Ρ ΡΠ΅ΠΎΡΠ΅ΡΠΈΡΠ΅ΡΠΊΠΈΠΌ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠ°ΠΌ. Π‘ Π΄ΡΡΠ³ΠΎΠΉ ΡΡΠΎΡΠΎΠ½Ρ, ΡΠ΅ΠΎΡΠ΅ΡΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΡΠ°ΡΡΠ΅ΡΡ ΠΏΡΠ΅Π΄ΡΠΊΠ°Π·ΡΠ²Π°ΡΡ, ΡΡΠΎ ΠΏΠΎ ΡΡΠ°Π²Π½Π΅Π½ΠΈΡ Ρ ΡΠ»ΡΡΡΠ°Π·Π²ΡΠΊΠΎΠ²ΡΠΌ ΡΠΏΠΎΡΠΎΠ±ΠΎΠΌ ΠΎΡΠ°ΠΆΠ΄Π΅Π½ΠΈΡ ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ ΡΠ»Π΅ΠΊΡΡΠΎΡΡΠ°ΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΡΠΏΠΎΡΠΎΠ±Π° Π±ΡΠ΄Π΅Ρ Π±ΠΎΠ»Π΅Π΅ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎ Π΄Π»Ρ Π°ΡΡΠΎΠ·ΠΎΠ»Π΅ΠΉ Ρ ΠΎΡΠ½ΠΎΡΠΈΡΠ΅Π»ΡΠ½ΠΎ Π±ΠΎΠ»Π΅Π΅ ΠΊΡΡΠΏΠ½ΡΠΌΠΈ ΡΠ°ΡΡΠΈΡΠ°ΠΌΠΈ.The relevance of the research is related to searching the efficient ways of deposition of fine aerosols to clean production rooms from dust and smoke. Development of methods of ensuring purity of air environment in production rooms are especially relevant in connection with the development of nanotechnologies as well as engineering chemistries, related to possible emissions of harmful and dangerous dust. The main aim of the research is searching for optimum ways of deposition of fine aerosols comparing electrostatic and ultrasonic deposition of particles. Objects of the research are fine aerosols and ways of their deposition. Methods: mathematical modeling, optical methods of measurement of distribution function of particles by the sizes and concentration of aerosol particles using the laser measuring system LID2M and the Malvern Spraytec analyzer. Results. The authors have carried out the theoretical analysis of sedimentation rates of particles of fine aerosols (diameter of particles ~1-20 Β΅m) in the presence of acoustic, electric field taking into account a drift in electric field, ultrasonic coagulation, and acoustic flows (Β«sound windΒ»). The key mechanisms of particles deposition depending on their size are defined that allows proposing the optimum ways of deposition of fine aerosols in each range of particle sizes. The mathematical model of acoustic coagulation is based on an integral form of the equation of Smolukhovsky. The paper introduces the results of the experimental study of the model aerosol (NaCl) particles deposition with the reference diameter of particles about 6 Β΅m by means of ultrasound and electrodeposition device. It is defined that application of these ways of deposition is essential (and it is approximately identical) and it accelerates considerably sedimentation of the model aerosol that corresponds to theoretical results. On the other hand, theoretical calculations predict that application of electrostatic way of deposition will be more effective in comparison with the ultrasonic one for aerosols with rather larger particles
DMT analysis of coherent free-space optical systems over atmospheric turbulence channels
Due to copyright restrictions, the access to the full text of this article is only available via subscription.In this paper, we investigate the diversity-multiplexing tradeoff (DMT) performance of a coherent free-space optical (FSO) communication system with multiple receive apertures over atmospheric turbulence channels. Our study builds on the recently introduced statistical model that characterizes the combined effects of turbulence-induced wavefront distortion and amplitude fluctuation in coherent receivers with phase compensation. Our results provide insight into performance mechanisms of coherent FSO systems and demonstrate significant performance gains that can be obtained through the deployment of multiple receive apertures and phase compensation techniques
Hepatocyte nuclear factor-4Ξ± is a central transactivator of the mouse Ntcp gene
Sodium taurocholate cotransporting polypeptide (Ntcp) is the major uptake system for conjugated bile acids. Deletions of hepatocyte nuclear factor (HNF)-1Ξ± and retinoid X receptor-Ξ±:retinoic acid receptor-Ξ± binding sites in the mouse 5β²-flanking region corresponding to putatively central regulatory elements of rat Ntcp do not significantly reduce promoter activity. We hypothesized that HNF-4Ξ±, which is increasingly recognized as a central regulator of hepatocyte function, may directly transactivate mouse (mNtcp). A 1.1-kb 5β²-upstream region including the mouse Ntcp promoter was cloned and compared with the rat promoter. In contrast to a moderate 3.5-fold activation of mNtcp by HNF-1Ξ±, HNF-4Ξ± cotransfection led to a robust 20-fold activation. Deletion analysis of mouse and rat Ntcp promoters mapped a conserved HNF-4Ξ± consensus site at β345/β326 and β335/β316 bp, respectively. p-475bpmNtcpLUC is not transactivated by HNF-1Ξ± but shows a 50-fold enhanced activity upon cotransfection with HNF-4Ξ±. Gel mobility shift assays demonstrated a complex of the HNF-4Ξ±-element formed with liver nuclear extracts that was blocked by an HNF-4Ξ± specific antibody. HNF-4Ξ± binding was confirmed by chromatin immunoprecipitation. Using Hepa 1β6 cells, HNF-4Ξ±-knockdown resulted in a significant 95% reduction in NTCP mRNA. In conclusion, mouse Ntcp is regulated by HNF-4Ξ± via a conserved distal cis-element independently of HNF-1Ξ±