10 research outputs found
Reasons for the weak correlation between prostate volume and urethral resistance parameters in patients with prostatism
In an attempt to increase our understanding of the clinical syndrome of
benign prostatic hyperplasia (BPH) an analysis was made of the association
between prostate volume as measured by transrectal ultrasound and several
reported urodynamically determined urethral resistance parameters. Two
types of obstruction can be recognized on the basis of urodynamic data: a
compressive type characterized by a high urethral opening pressure and a
prolonged isovolumetric contraction phase before urine flow can start, and
a constrictive type characterized by a normal opening pressure and an
increased slope of the urethral resistance relation. A combination of both
types is often seen in BPH. In our study, parameters that selectively
quantify compression correlate weakly to moderately with prostate volume,
whereas parameters that mainly quantify constriction do not correlate at
all with prostate volume. Parameters that combine a measure for
compression and constriction correlate less well with prostate volume than
parameters that mainly quantify compression. The variation in prostate
volume was found to determine the variation in urethral resistance by 15%
or less depending on the parameter used, which implies that the different
pathophysiological mechanisms that can increase urethral resistance in the
complex process of clinical BPH are mainly determined by factors other
than the volume of the prostate. Thus, despite the lack of correlation
between prostate volume and urethral resistance, pressure-flow studies and
the determination of urethral resistance parameters provide a valuable
contribution to the understanding of the pathophysiology of voiding
dysfunction in men with symptoms of prostatism
The effects of transurethral resection of the prostate on morbidity and mortality in patients with nondialysis-requiring renal insufficiency
Objectives: To compare the prevalence of preoperative co-morbid factors and complications of transurethral resection of prostate (TUR-P) in patients with normal and non-dialysis requiring elevated serum creatinine levels