OCCULT FOLLICULAR THYROID CARCINOMA - AN UNUSUALPRESENTATION OF MULTIPLE LYTIC BONY METASTASIS IN THE SKULL OF A 66-YEAR MALAY MAN

Follicular carcinoma of the thyroid usually presents as nodules with rare cases showing metastasis at diagnosis. But occult follicular carcinoma without any thyroid enlargement and presenting as multiple lytic bone lesions is unusual and relatively rare. Here we report a 66-year old Malay man presenting with occipito-parietal swelling for last two years. He had no thyroid enlargement; no thyroid related symptoms and his biochemical thyroid profile was normal. Computerised tomography of skull reported multiple lytic lesions in the occipito-parietal region. FNAC and histopathological examination confirmed the diagnosis of metastatic follicular carcinoma. We present this case because of the rarity of the disease. Ibrahim Med. Coll. J. 2007; 1(2): 25-2

Distribution of phenotypic and genotypic ABO and rhesus blood groups among Bangladeshi population

The present study is a retrospective analysis of allelic frequency of ABO and Rhesus (D) blood groups of donors attending the Deaprtment of Transfusion Medicine of Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM), Dhaka. BIRDEM IS a 625 bed hospital, where patients and blood donors come from all parts of Bangladesh. A total of 1, 28,506 blood donors of both genders were included in the study over fourteen years from June 1995 to June 2009 for analysis. Blood group was determined by performing the both tube and slide method blood grouping method. The distribution of blood groups in our population was B>O>A>AB in Rh positive groups donors and O>B>A>AB among Rh negative donors. Blood group B was more common among the males (37.42%) while O was predominant among female donors (33.83 %). On the other hand, blood group O negative was predominant in both genders (36.88%). In this study, Hardy- Weinberg equilibrium law was used to calculate the allelic frequency for ABO/ Rh system. Homozygous allelic frequency for Rh negative population was only 0.0007. Although phenotypically B group was dominant and AB was rare in our population, but according to Hardy- Weinberg equilibrium law the estimatedallelic frequency of A (0.3694) and O (0.3040) showed higher frequency than B type (0.2300) in Bangladeshi population in both homozygous and heterozygous state. So, with increasing population of Bangladesh, this changing trend in estimated blood group in ABO system may play an important role in our genetic pattern. Ibrahim Med. Coll. J. 2011; 5(2): 59-6

Vaginal Schwannoma

Vaginal Schwannoma is very rare and till now few cases have been reported in the literature. A case of vaginal Schwannoma is reported here. The patient was a 59 years old woman with the complaints of per vaginal bleeding with an attempt of D&C failure. Ultimately hysterectomy was done and the diagnosis of Vaginal Schwannoma was made on histopathological examination of the excised tumor. Clinicians should be aware and bear in mind about the differential diagnosis of vaginal Schwannoma in case of any per vaginal bleeding. Ibrahim Med. Coll. J. 2010; 4(2): 90-9

CASE REPORT - MALIGNANT MIXED MULLERIAN TUMOUR, HETEROLOGOUS IN A 66-YEAR-OLD MALAY LADY - A CASE REPORT.

A 66-year-old Malay woman, known hypertensive, presented with post menopausal bleeding associated with clot for three months. She was postmenopausal for last ten years. She also complaints of developing a mass in the abdomen which was growing in size also for last three months. Abdominal examination revealed a twenty week size mass, movable from side to side but unable to get below the mass. Vaginal examination revealed a fleshy fungating mass arising from the uterus coming out through the vagina. Cervix could not be visualized properly. Subsequent histopathology of the removed mass was reported as a Malignant Mixed Mullerian Tumour - Heterologous