Infrared images of merging galaxies

Infrared imaging of interacting galaxies is especially interesting because their optical appearance is often so chaotic due to extinction by dust and emission from star formation regions, that it is impossible to locate the nuclei or determine the true stellar distribution. However, at near-infrared wavelengths extinction is considerably reduced, and most of the flux from galaxies originates from red giant stars that comprise the dominant stellar component by mass. Thus near infrared images offer the opportunity to study directly components of galactic structure which are otherwise inaccessible. Such images may ultimately provide the framework in which to understand the activity taking place in many of the mergers with high Infrared Astronomy Satellite (IRAS) luminosities. Infrared images have been useful in identifying double structures in the nuclei of interacting galaxies which have not even been hinted at by optical observations. A striking example of this is given by the K images of Arp 220. Graham et al. (1990) have used high resolution imaging to show that it has a double nucleus coincident with the radio sources in the middle of the dust lane. The results suggest that caution should be applied in the identification of optical bright spots as multiple nuclei in the absence of other evidence. They also illustrate the advantages of using infrared imaging to study the underlying structure in merging galaxies. The authors have begun a program to take near infrared images of galaxies which are believed to be mergers of disk galaxies because they have tidal tails and filaments. In many of these the merger is thought to have induced exceptionally luminous infrared emission (cf. Joseph and Wright 1985, Sanders et al. 1988). Although the optical images of the galaxies show spectacular dust lanes and filaments, the K images all have a very smooth distribution of light with an apparently single nucleus

Application of Dynamic System Identification to Timber Bridges

A method of global nondestructive evaluation for identifying local damage and decay in timber beams was developed in previous analytical studies and verified experimentally using simply supported beams in the laboratory. The method employs experimental modal analysis and an algorithm that monitors changes in modal strain energy between the mode shapes of a damaged structure with respect to the undamaged structure. A simple three-girder bridge was built and tested in a laboratory to investigate the capability and limitations of the method for detecting damage in a multimember timber structure. The laboratory tests showed that the method can correctly detect and locate a simulated pocket of decay inflicted at the end of a girder as well as detect a notch removed from the midspan of a girder. The tests showed that the method can correctly detect damage simultaneously at two locations within the bridge, but also that large magnitudes of damage at one location can mask smaller magnitudes of damage at another location. When a calibrated baseline model is used to represent the undamaged state of the bridge, the results show that the method of nondestructive evaluation is able to detect each case of inflicted damage, but with some increase in localization error

Risk assessment and predicting outcomes in patients with depressive symptoms: a review of potential role of peripheral blood based biomarkers

Depression is one of the major global health challenges and a leading contributor of health related disability and costs. Depression is a heterogeneous disorder and current methods for assessing its severity in clinical practice rely on symptom count, however this approach is unreliable and inconsistent. The clinical evaluation of depressive symptoms is particularly challenging in primary care, where the majority of patients with depression are managed, due to the presence of co-morbidities. Current methods for risk assessment of depression do not accurately predict treatment response or clinical outcomes. Several biological pathways have been implicated in the pathophysiology of depression; however, accurate and predictive biomarkers remain elusive. We conducted a systematic review of the published evidence supporting the use of peripheral biomarkers to predict outcomes in depression, using Medline and Embase. Peripheral biomarkers in depression were found to be statistically significant predictors of mental health outcomes such as treatment response, poor outcome and symptom remission; and physical health outcomes such as increased incidence of cardiovascular events and deaths, and all-cause mortality. However, the available evidence has multiple methodological limitations which must be overcome to make any real clinical progress. Despite extensive research on the relationship of depression with peripheral biomarkers, its translational application in practice remains uncertain. In future, peripheral biomarkers identified with novel techniques and combining multiple biomarkers may have a potential role in depression risk assessment but further research is needed in this area

K-Band Spectroscopy of an Obscured Massive Stellar Cluster in the Antennae Galaxies (NGC 4038/4039) with NIRSPEC

We present infrared spectroscopy of the Antennae Galaxies (NGC 4038/4039) with NIRSPEC at the W. M. Keck Observatory. We imaged the star clusters in the vicinity of the southern nucleus (NGC 4039) in 0.39" seeing in K-band using NIRSPEC's slit-viewing camera. The brightest star cluster revealed in the near-IR (M_K(0) = -17.9) is insignificant optically, but coincident with the highest surface brightness peak in the mid-IR (12-18 um) ISO image presented by Mirabel et al (1998). We obtained high signal-to-noise 2.03-2.45 um spectra of the nucleus and the obscured star cluster at R = 1900. The cluster is very young (age ~ 4 Myr), massive (M ~ 16E6 M_sun), and compact (density ~ 115 M_sun pc^(-3) within a 32 pc half-light radius), assuming a Salpeter IMF (0.1-100 M_sun). Its hot stars have a radiation field characterized by T_eff ~ 39,000 K, and they ionize a compact HII region with n_e ~ 10^4 cm^(-3). The stars are deeply embedded in gas and dust (A_V = 9-10 mag), and their strong FUV field powers a clumpy photodissociation region with densities n_H > 10^5 cm^(-3) on scales of ~ 200 pc, radiating L{H_2 1-0 S(1)}= 9600 L_sun.Comment: 4 pages, 4 embedded figures, uses emulateapj.sty. To appear in ApJL. Also available at http://astro.berkeley.edu/~agilber

The Smallest Mass Ratio Young Star Spectroscopic Binaries

Using high resolution near-infrared spectroscopy with the Keck telescope, we have detected the radial velocity signatures of the cool secondary components in four optically identified pre-main-sequence, single-lined spectroscopic binaries. All are weak-lined T Tauri stars with well-defined center of mass velocities. The mass ratio for one young binary, NTTS 160905-1859, is M2/M1 = 0.18+/-0.01, the smallest yet measured dynamically for a pre-main-sequence spectroscopic binary. These new results demonstrate the power of infrared spectroscopy for the dynamical identification of cool secondaries. Visible light spectroscopy, to date, has not revealed any pre-main-sequence secondary stars with masses <0.5 M_sun, while two of the young systems reported here are in that range. We compare our targets with a compilation of the published young double-lined spectroscopic binaries and discuss our unique contribution to this sample.Comment: Accepted for publication in the April, 2002, ApJ; 6 figure

Biological Records Centre Annual Report 2005-2006

The period covered by this report is the first year of a new six-year partnership between CEH and JNCC. For this period, there is increased emphasis on targeted survey, on analysis and interpretation and on communications and outreach. These activities were always part of BRC’s work, but they have been given greater prominence as a result of rapid developments in information technology. Data are increasingly reaching BRC in electronic form, so that the effort of data entry and collation is reduced. The data, collected by many volunteers and then collated and analysed at BRC, document the changing status and distribution of plants and animals in Britain. Distribution maps are published in atlases and are available via the internet through the NBN Gateway. The effects of change or loss of habitats, the influence of climate change and the consequences of changing water quality are all examples of the environmental factors that affect our biodiversity and which BRC aims to document and understand. The results are vital for developing environmental policies, to support conservation, and for fundamental ecological research. BRC is funded jointly by JNCC and NERC through a partnership based on a Memorandum of Agreement (MoA). The partnership started in 1973 when the Nature Conservancy was divided to form the successor bodies Nature Conservancy Council (NCC) and Institute of Terrestrial Ecology (ITE). NCC was in turn divided further to form JNCC and three Country Agencies, while ITE was merged with other NERC units to form CEH. Through all these changes, the partnership has been maintained. A six-year memorandum of agreement ended on 31 January 2005 (Hill et al. 2005). The present report covers the first full year, 2005-6, of the new agreement for 2005-2010. Rapid progress in information technology continues to be highly beneficial for BRC, whose data are increasingly used by the UK country conservation agencies, environmental consultants, NGOs, research workers, policy makers and volunteers. It is gratifying to know that, through our ability to display data on the National Biodiversity Network (NBN) Gateway, some of our data suppliers now have immediate access to their own data in a convenient form. The year 2005-6 has been one of steady progress, with new datasets added to BRC, substantial additions to existing data, and improved communication with the NBN Gateway. The most high profile activity of the year has been the Harlequin Ladybird Survey, which has enabled us to observe the early stages of colonization by a mobile insect in greater detail than has been possible in any previous case

Spectropolarimetric observations of Herbig Ae/Be Stars I: HiVIS spectropolarimetric calibration and reduction techniques

Using the HiVIS spectropolarimeter built for the Haleakala 3.7m AEOS telescope in Hawaii, we are collecting a large number of high precision spectropolarimetrc observations of stars. In order to precisely measure very small polarization changes, we have performed a number of polarization calibration techniques on the AEOS telescope and HiVIS spectrograph. We have extended our dedicated IDL reduction package and have performed some hardware upgrades to the instrument. We have also used the ESPaDOnS spectropolarimeter on CFHT to verify the HiVIS results with back-to-back observations of MWC 361 and HD163296. Comparision of this and other HiVIS data with stellar observations from the ISIS and WW spectropolarimeters in the literature further shows the usefulness of this instrument.Comment: 35 pages, 44 figures, Accepted by PAS

Significance of Reoxiation in Steelmaking

In recent years, reoxidation has clearly emerged as a major source of non-metallic inclusion in steel, and the main contributory causes have been clarified. These are direct oxidation of the steel stream as it falls through the air, chemical erosion of siliceous refrectories and oxidation by aie entrained during casting, the last being the most important. In spite of this the factors governing entrainment are not well understood. Consequently, in this work, falling water jets were used to carry out through investigation of the effects of nozzle diameter, height of fall, discharge rate and turbulence level of the stream an jet disintegration, the rate at which air is entrained and the volume of air retained in the receiving pool during-pouring. Of the variable employed, the turbulence level emerges as the most important. Four mechanisms of entra-inment were distinguished and their relative contributions to the overall rates elucidated. The way in which entra-ined air is distributed as bubbles, their residence times and their effect on flow patterns within the receiving pool are mentioned, since these factors influence the gas-metal area and time available for oxygen pick-up. Exper-iments have also been conducted to study gas absorption by molten steel droplets falling through air. The pract-ical implications of the results are discussed with refe-rence to the reactions which occur as steel is trans-ferred from the furnace to the ladle and then to the ingot mould. The influence of reoxidation on alloy loss, slag formation, refractory interactions, sulphide shape cont-rol and steel cleanliness are described and the paper concludes wiht a discussion of the critical importance of controlling stream characteristics and eliminating air entrainment

The molecular genetic analysis of the expanding pachyonychia congenita case collection

BACKGROUND: Pachyonychia congenita (PC) is a rare autosomal dominant keratinizing disorder characterized by severe, painful, palmoplantar keratoderma and nail dystrophy, often accompanied by oral leucokeratosis, cysts and follicular keratosis. It is caused by mutations in one of five keratin genes: KRT6A, KRT6B, KRT6C, KRT16 or KRT17. OBJECTIVES: To identify mutations in 84 new families with a clinical diagnosis of PC, recruited by the International Pachyonychia Congenita Research Registry during the last few years. METHODS: Genomic DNA isolated from saliva or peripheral blood leucocytes was amplified using primers specific for the PC-associated keratin genes and polymerase chain reaction products were directly sequenced. RESULTS: Mutations were identified in 84 families in the PC-associated keratin genes, comprising 46 distinct keratin mutations. Fourteen were previously unreported mutations, bringing the total number of different keratin mutations associated with PC to 105. CONCLUSIONS: By identifying mutations in KRT6A, KRT6B, KRT6C, KRT16 or KRT17, this study has confirmed, at the molecular level, the clinical diagnosis of PC in these families

Carbon assimilation strategies in ultrabasic groundwater: clues from the integrated study of a serpentinization-influenced aquifer

© The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Seyler, L. M., Brazelton, W. J., McLean, C., Putman, L. I., Hyer, A., Kubo, M. D. Y., Hoehler, T., Cardace, D., & Schrenk, M. O. . Carbon assimilation strategies in ultrabasic groundwater: clues from the integrated study of a serpentinization-influenced aquifer. mSystems, 5(2), (2020): e00607-00619, doi: 10.1128/mSystems.00607-19.Serpentinization is a low-temperature metamorphic process by which ultramafic rock chemically reacts with water. Such reactions provide energy and materials that may be harnessed by chemosynthetic microbial communities at hydrothermal springs and in the subsurface. However, the biogeochemistry mediated by microbial populations that inhabit these environments is understudied and complicated by overlapping biotic and abiotic processes. We applied metagenomics, metatranscriptomics, and untargeted metabolomics techniques to environmental samples taken from the Coast Range Ophiolite Microbial Observatory (CROMO), a subsurface observatory consisting of 12 wells drilled into the ultramafic and serpentinite mélange of the Coast Range Ophiolite in California. Using a combination of DNA and RNA sequence data and mass spectrometry data, we found evidence for several carbon fixation and assimilation strategies, including the Calvin-Benson-Bassham cycle, the reverse tricarboxylic acid cycle, the reductive acetyl coenzyme A (acetyl-CoA) pathway, and methylotrophy, in the microbial communities inhabiting the serpentinite-hosted aquifer. Our data also suggest that the microbial inhabitants of CROMO use products of the serpentinization process, including methane and formate, as carbon sources in a hyperalkaline environment where dissolved inorganic carbon is unavailable.We thank McLaughlin Reserve, in particular Paul Aigner and Cathy Koehler, for hosting sampling at CROMO and providing access to the wells, A. Daniel Jones and Anthony Schilmiller for their advice regarding metabolite extraction and mass spectrometry, Elizabeth Kujawinski for her guidance in metabolomics data analysis and interpretation, and Julia McGonigle, Christopher Thornton, and Katrina Twing for assistance with metagenomic and computational analyses