Object-Oriented Paradigms for Modelling Vascular\ud Tumour Growth: a Case Study

Motivated by a family of related hybrid multiscale models, we have built an object-oriented framework for developing and implementing multiscale models of vascular tumour growth. The models are implemented in our framework as a case study to highlight how object-oriented programming techniques and good object-oriented design may be used effectively to develop hybrid multiscale models of vascular tumour growth. The intention is that this paper will serve as a useful reference for researchers modelling complex biological systems and that these researchers will employ some of the techniques presented herein in their own projects

Influence of surface anisotropy on exchange resonance modes in spherical shells

This is the author accepted manuscript. The final version is available from IOP Publishing via the DOI in this recordThe dynamical properties of saturated spherical shells are investigated in the exchange-dominated regime when assuming that surface anisotropy is present at both the inner and outer boundaries. It is found that surface anisotropy plays an important role in determining the dependence of lower-order eigenvalues on shell thickness. The mode frequency can increase with decreasing shell thickness, or is driven rapidly towards the ferromagnetic resonance frequency depending on the choice of the surface anisotropy constant at each boundary. The presence of surface anisotropy significantly modifies the size dependence of the modes which can be suppressed or amplified based on the coupling between boundaries. When surface anisotropy is present only on the outer boundary, similar behaviour to the solid sphere is observed for lower-order eigenvalues up to a thickness of after which large deviations begin to occur, where and are the inner and outer radius, respectively. Moreover, surface anisotropy introduces a dependence of the zeroth mode on shell thickness, removing the degeneracy with the ferromagnetic resonance and leading to a pronounced size dependence of this mode for thin shells.The authors acknowledge financial support from the Defense Science and Technology Laboratory (DSTL) and the Engineering and Physical Sciences Research Council (EPSRC) of the United Kingdom, via the EPSRC Centre for Doctoral Training in Electromagnetic Metamaterials (Grant No. EP/L015331/1)

Training Forensic Graduate Assistants: A Development Course

We have created a course which is geared towards helping the forensic graduate assistant. The focus of the course is the role of the individual events assistant; however, changes can made to adapt to an assistant who helps with a debate or combined forensics program. A suggested course outline is offered, as well as specific information and activities pertaining to the basic areas of study within the course. Following this, further suggestions and considerations offered

Cavity QED with Single Atoms and Photons

Recent experimental advances in the field of cavity quantum electrodynamics (QED) have opened new possibilities for control of atom-photon interactions. A laser with "one and the same atom" demonstrates the theory of laser operation pressed to its conceptual limit. The generation of single photons on demand and the realization of cavity QED with well defined atomic numbers N = 0, 1, 2,... both represent important steps toward realizing diverse protocols in quantum information science. Coherent manipulation of the atomic state via Raman transitions provides a new tool in cavity QED for in situ monitoring and control of the atom-cavity system. All of these achievements share a common point of departure: the regime of strong coupling. It is thus interesting to consider briefly the history of the strong coupling criterion in cavity QED and to trace out the path that research has taken in the pursuit of this goal

Admission to hospital in the UK at a weekend does not influence the prognosis of adults with community-acquired pneumonia

Outcomes for adults with community-acquired pneumonia (CAP) admitted to hospital at the weekend were compared with those admitted during weekdays using data from the British Thoracic Society national CAP audits. Of 31 400 cases, 40.7% were weekend admissions; these patients were older (mean age 72 vs 71.3 years, p=0.001) and more likely to have high severity CAP (28.9% vs 27.1%, p trend 0.003) but had slightly lower adjusted 30-day inpatient mortality (aOR 0.94 95% CI 0.88 to 1.01) compared with those admitted during weekdays. More patients in the weekend group received antibiotics within 4 hours of admission (70.3% vs 68.7%, aOR 1.07 95% CI 1.01 to 1.12). We did not observe increased mortality for adults admitted at the weekend with CAP

Collective Oscillations of an Imbalanced Fermi Gas: Axial Compression Modes and Polaron Effective Mass

We investigate the low-lying compression modes of a unitary Fermi gas with imbalanced spin populations. For low polarization, the strong coupling between the two spin components leads to a hydrodynamic behavior of the cloud. For large population imbalance we observe a decoupling of the oscillations of the two spin components, giving access to the effective mass of the Fermi polaron, a quasi-particle composed of an impurity dressed by particle-hole pair excitations in a surrounding Fermi sea. We find $m^*/m=1.17(10)$, in agreement with the most recent theoretical predictions.Comment: 4 pages, 4 figures, submitted to PR