5,663 research outputs found

    Changes in life quality following third molar surgery

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    Interpreting Photoactive Fluorescence Microscopy Measurements of Steady-State Actin Dynamics

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    Biophysical Journal, 1995A continuum model describing the steady-state actin dynamics of the cytoskeleton of living cells Has been developed to aid in the interpretation of photoactivated fluorescence experiments. In a simplified cell geometry, the model assumes uniform concentrations of cytosolic and cytoskeletal actin throughout the cell and no net growth of either pool. The spatiotemporal evolution of the fluorescent actin population is described by a system of two coupled linear partial-differential equations. An analytical solution is found using a Fourier-Laplace transform and important limiting cases relevant to the design of experiments are discussed. The results demonstrate that, despite being a complex function of the parameters, the fluorescence decay in photoactivated fluorescence experiments has a biphasic behavior featuring a short-term decay controlled by monomer diffusion and a long-term decay governed by the monomer exchange rate between the polymerized and unpolymerized actin pools. This biphasic behavior suggests a convenient mechanism for extracting the parameters governing the fluorescence decay from data records. These parameters include the actin monomer diffusion coefficient, filament turnover rate, and ratio of polymerized to unpolymerized actin

    Patient centered outcome measures in oral surgery: validity and sensitivity issues

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    MOTOR UNIT FIRINGS DURING VOLUNTARY ISOMETRIC RAMP AND BALLISTIC CONTRACTIONS IN HUMAN VASTUS MEDIALIS MUSCLE

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    Intra-muscular electromyographic (EMG) signals in vastus medialis muscle were decomposed into their constituent motor unit action potential trains using a specially designed quadrifilar wire electrode during voluntary isometric ramp and ballistic contractions. Five male adults participated in our experiments as subjects and performed ramp trapezoidal, ramp triangular, and ballistic contractions. By using a newly developed wire electrode, intra-muscular EMG signals were successfully decomposed into the individual motor unit action potential trains. The firing behaviors analyzed by the decomposition technique were consistent with previous studies on small muscles. This new quadrifilar wire electrode is potentially a useful tool for detecting intra-muscular electromyographic signals in large limb muscles such as the vastus medialis

    What are patients' expectations of orthodontic treatment: a systematic review

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    Anatomy Of The Upper Airway And Its Growth In Childhood

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    Because several craniofacial anomalies are related to the narrow upper airway, for example narrow maxilla or retruded mandible, orthodontists and oral and maxillofacial surgeons are involving diagnosis and treatment of paediatric obstructive sleep apnoea. The knowledge of anatomy of the upper airway and its growth change in childhood is crucial for both clinical and research purposes.published_or_final_versio

    Tooth eruption and obesity in 12-year-old children

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