Prolactin

During an oral glucose tolerance test (OGTT) glucose and insulin levels were measured in 26 patients with prolactin-producing pituitary tumours without growth hormone excess. Basal glucose and insulin levels did not differ from the values of an age-matched control group. After glucose load the hyperprolactinaemic patients showed a decrease in glucose tolerance and a hyperinsulinaemia. Bromocriptine (CB 154), which suppressed PRL, improved glucose tolerance and decreased insulin towards normal in a second OGTT. — Human PRL or CB 154 had no significant influence on insulin release due to glucose in the perfused rat pancreas. — These findings suggest a diabetogenic effect of PRL. CB 154 might be a useful drug in improving glucose utilization in hormone-active pituitary tumours

A New efficient dynamic MAC protocol for the delivery of multiple services over GPON

“The original publication is available at www.springerlink.com”. Copyright Springer. [Full text of this article is not available in the UHRA]The Gigabit-capable passive optical network (GPON) has become an attractive and promising solution for the broadband access network. It is apparent that an efficient medium access control (MAC) protocol is crucial not only to catalyze the utilization of the upstream resources but also to support the GPON encapsulation method (GEM) for multiple services over GPON. A new approach for bandwidth reporting is developed to achieve dynamic awareness of both the changes of ONU queue status and the consequences of previous allocations. In addition, a novel balance transferring mechanism that enables a register and transfer process for successive allocation across multiple frames is presented. By incorporating the new schemes of bandwidth reporting process and the balance transferring mechanism into a frame-based scheduling procedure, an efficient dynamic bandwidth assignment MAC protocol is developed to support differentiated services over GPON. The performance of the new protocol is simulated and evaluated under a variety of traffic distributions. Simulated characteristics demonstrate a significantly improved network performance.Peer reviewe