24 research outputs found

    Precision Medicine in Diabetes: A Consensus Report From the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)

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    The convergence of advances in medical science, human biology, data science, and technology has enabled the generation of new insights into the phenotype known as "diabetes." Increased knowledge of this condition has emerged from populations around the world, illuminating the differences in how diabetes presents, its variable prevalence, and how best practice in treatment varies between populations. In parallel, focus has been placed on the development of tools for the application of precision medicine to numerous conditions. This Consensus Report presents the American Diabetes Association (ADA) Precision Medicine in Diabetes Initiative in partnership with the European Association for the Study of Diabetes (EASD), including its mission, the current state of the field, and prospects for the future. Expert opinions are presented on areas of precision diagnostics and precision therapeutics (including prevention and treatment), and key barriers to and opportunities for implementation of precision diabetes medicine, with better care and outcomes around the globe, are highlighted. Cases where precision diagnosis is already feasible and effective (i.e., monogenic forms of diabetes) are presented, while the major hurdles to the global implementation of precision diagnosis of complex forms of diabetes are discussed. The situation is similar for precision therapeutics, in which the appropriate therapy will often change over time owing to the manner in which diabetes evolves within individual patients. This Consensus Report describes a foundation for precision diabetes medicine, while highlighting what remains to be done to realize its potential. This, combined with a subsequent, detailed evidence-based review (due 2022), will provide a roadmap for precision medicine in diabetes that helps improve the quality of life for all those with diabetes.This article is freely available via Open Access. Click on the publisher URL to access it via the publisher's site.R01 HD094150/HD/NICHD NIH HHS/United States DP3 DK111906/DK/NIDDK NIH HHS/United States U01 DK105535/DK/NIDDK NIH HHS/United States R01 DK104942/DK/NIDDK NIH HHS/United States U54 DK118612/DK/NIDDK NIH HHS/United States R21 AI142483/AI/NIAID NIH HHS/United States R01 DK122586/DK/NIDDK NIH HHS/United States P30 DK026687/DK/NIDDK NIH HHS/United States WT_/Wellcome Trust/United Kingdom R01 DK052431/DK/NIDDK NIH HHS/United States UL1 TR001873/TR/NCATS NIH HHS/United States R01 DK104351/DK/NIDDK NIH HHS/United Statesaccepted version, submitted versio

    Women Psychologists within Academic Health Systems: Mentorship and Career Advancement

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    Women are underrepresented on the faculties and within the senior leadership ranks of academic health systems. Nevertheless, despite the continuing existence of career development challenges related to gender, it is possible for women to thrive professionally in these settings. Mentorship is extremely important, and it is argued that effective mentorship is facilitated by an understanding of both gender differences in social behaviors and the culture of academic health systems. Furthermore, a systemsā€™ level emphasis on faculty diversity and the career development of women faculty is recommended.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/44857/1/10880_2005_Article_5746.pd

    Windows of Opportunity: When and How Can the Policy Analyst Influence the Policymaker During the Policy Process

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    Building on a variety of conceptualizations about the policymaker, the policy analyst, and the policy process, this essay seeks to understand how these three aspects mesh together. Consequently, this paper attempts to examine four questions that are germane to the analysis of policy: What roles can the policy analyst play? What are the personality types of policymakers? What is the role of the policymaker's personality in the policy process? What are the windows of opportunity for the policy analyst in one's attempt to influence the policymaker during the policy process? This paper argues that the policy analyst has the opportunity to influence policymakers at various stages of the policy process. However, the influence strategies that are effective are different depending upon the type of policymaker. This understanding is vital if a policy analyst desires to have an impact. Furthermore, the role the analyst performs has a significant impact on the how and the extent to which the analyst may have leverage. Copyright 1995 by The Policy Studies Organization.
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