38 research outputs found
Allergic Gingivostomatitis (Due to Gum Chewing)
Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/141962/1/jper0709.pd
Mucoepidermoid carcinoma associated with acute lymphoblastic leukemia
As treatment and survival of acute leukemia as well as other types of pediatric cancer improve, the number of second malignancies in these treated patients will increase. Occurrence of these second malignancies in the head and neck is not frequently reported although it is known that radiation treatment, chemotherapy and sometimes the primary lesion itself are risk factors for neoplasia. Malignancies of the parotid gland in the pediatric population are known to be unusual. We discuss a mucoepidermoid carcinoma in a 10-year-old female who 7 years earlier had undergone successful treatment of acute lymphoblastic leukemia.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/30289/1/0000691.pd
Metastatic carcinoma to the sphenoid sinus case report and review of the literature
Metastatic carcinoma to the sphenoid sinus is a rare event. A case of metastatic adenocarcinoma from the prostate gland to the sphenoid sinus and diagnosed with the aid of immunoperoxidase staining is presented. A concurrent review of the literature uncovered only 17 previously reported cases of carcinoma metastatic to the sphenoid sinus. Among these cases, adenocarcinoma from the large bowel and prostate gland predominated.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/47269/1/405_2004_Article_BF00453691.pd
ADULT T-CELL LEUKAEMIA-LYMPHOMA WITH UNUSUAL PHENOTYPE
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/23771/1/0000007.pd
Case report 427
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/46783/1/256_2004_Article_BF00361481.pd
Facial nerve paresis as the presenting symptom of leukemia
Leukemic involvement of the temporal bone is not uncommon and may present in a variety of ways including auricular or external canal skin lesions, red or thick tympanic membrane, middle ear effusions, otitis media, hearing loss or mastoiditis. Symptomatic facial nerve involvement, on the other hand, is extremely unusual. We discuss a pediatric patient whose sudden onset facial nerve paresis was the presenting symptom that led to her diagnosis of leukemia. At the time of mastoidectomy, a granulocytic sarcoma or chloroma was noted to be overlying the VIIth nerve.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/28445/1/0000233.pd
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High-Risk Human Papillomavirus Types and Squamous Cell Carcinoma in Patients with Respiratory Papillomas
Respiratory papillomas (RPs) are benign, virally induced tumors of the larynx and respiratory epithelium that may obstruct the airway and tend to recur frequently. RPs are thought to be the result of infection with the human papillomaviruses (HPVs) types 6 and 11. We surveyed archival RP specimens to determine whether there were correlations of HPV type with patient characteristics or clinical course. Paraffin-embedded papilloma specimens of 45 different patients were analyzed. We assessed HPV types using the polymerase chain reaction with E6 consensus primers, hybrid capture assays (high or low risk), and dot blot hybridization of generic E6 PCR products with E6 type-specific oligonucleotide probes. The presence and type of HPV were correlated with patient data from a retrospective chart review. We found that RPs may have either low- or high-risk HPV types and some contain multiple HPV types. Respiratory infection with high-risk HPV apparently introduces a long-term risk of squamous cell carcinoma development, even in the absence of conventional cofactors. Low-risk HPV infection may also act in association with these cofactors to promote carcinogenesis. Our data also show a racial imbalance in RP that may indicate a difference in genetic resistance and/or susceptibility to HPV infection and the development of RP