Thermal formation of carbynes

We simulate the formation of $sp$ carbon chains (carbynes) by thermal decomposition of $sp^2$ carbon heated by a hot discharge plasma, by means of tight-binding molecular dynamics. We obtain and analyze the total quantity of carbynes and their length distribution as a function of temperature and density

Experimental evidence of planar channeling in a periodically bent crystal

The usage of a Crystalline Undulator (CU) has been identified as a promising solution for generating powerful and monochromatic $\gamma$-rays. A CU was fabricated at SSL through the grooving method, i.e., by the manufacturing of a series of periodical grooves on the major surfaces of a crystal. The CU was extensively characterized both morphologically via optical interferometry at SSL and structurally via X-ray diffraction at ESRF. Then, it was finally tested for channeling with a 400 GeV/c proton beam at CERN. The experimental results were compared to Monte Carlo simulations. Evidence of planar channeling in the CU was firmly observed. Finally, the emission spectrum of the positron beam interacting with the CU was simulated for possible usage in currently existing facilities

ITGB2 mutation combined with deleted ring 21 chromosome in a child with leukocyte adhesion deficiency

Leukocyte adhesion deficiency type 1(LAD-1) is a rare autosomal recessive primary immunodeficiency caused by defects in the ITGB2 gene located on chromosome 21q22. Clinically, LAD-1 patients are characterized by recurrent infections, slow wound healing and dystrophic scars after skin injuries, associated with persistent neutrophilia. The severity of symptoms is related to the level of CD11/CD18 expression on patients’ leucocytes and those with less than 1% expression treated with hematopoietic stem cell transplant (HSCT). We present a child affected by LAD-1 who received HSCT from a matched unrelated donor. Molecular analysis revealed apparent homozygosis for a point mutation in the ITGB2 gene, only the mother however was carrier of the mutation. Cytogenetic and FISH analysis showed the presence of a de-novo ring chromosome 21. Whole Genome Analysis with the Affymetrix GeneChip Human Mapping 250K NspI array confirmed in the child the presence of a de novo deletion of the chromosomal region 21q22.3-qter, where the ITGB2 gene maps. While HSCT resulted in successful engraftment and correction of the immunodeficiency, all the phenotypic features of ring (21) syndrome with a deletion of a 4.6Mb (including 69 genes) clearly remained unchange

Steering efficiency of a ultrarelativistic proton beam in a thin bent crystal

Crystals with small thickness along the beam exhibit top performance for steering particle beams through planar channeling. For such crystals, the effect of nuclear dechanneling plays an important role because it affects their efficiency. We addressed the problem through experimental work carried out with 400 GeV/c protons at fixed-target facilities of CERN-SPS. The dependence of efficiency vs. curvature radius has been investigated and compared favourably to the results of modeling. A realistic estimate of the performance of a crystal designed for LHC energy including nuclear dechanneling has been achieved

A deep 1.4 GHz survey of the J1030 equatorial field: a new window on radio source populations across cosmic time

We present deep L-Band observations of the equatorial field centered on the z=6.3 SDSS QSO, reaching a 1 sigma sensitivity of ~2.5 uJy at the center of the field. We extracted a catalog of 1489 radio sources down to a flux density of ~12.5 uJy (5 sigma) over a field of view of ~ 30' diameter. We derived the source counts accounting for catalog reliability and completeness, and compared them with others available in the literature. Our source counts are among the deepest available so far, and, overall, are consistent with recent counts' determinations and models. We detected for the first time in the radio band the SDSS J1030+0524 QSO (26 +/- 5 uJy). We derived its optical radio loudness R_O = 0.62 +/- 0.12, which makes it the most radio quiet AGN at z >~ 6 discovered so far and detected at radio wavelengths. We unveiled extended diffuse radio emission associated with the lobes of a bright FRII radio galaxy located close to the center of the J1030 field, which is likely to become the future BCG of a protocluster at z=1.7. The lobes' complex morphology, coupled with the presence of X-ray diffuse emission detected around the FRII galaxy lobes, may point toward an interaction between the radio jets and the external medium. We also investigated the relation between radio and X-ray luminosity for a sample of 243 X-ray-selected objects obtained from 500 ks Chandra observations of the same field, and spanning a wide redshift range (0 ~< z ~< 3). Focused on sources with a spectroscopic redshift and classification, we found that sources hosted by ETG and AGN follow Log(L_R)/Log(L_X) linear correlations with slopes of ~0.6 and ~0.8, respectively. This is interpreted as a likely signature of different efficiency in the accretion process. Finally, we found that most of these sources (>~87%) show a radio-to-X-ray radio loudness R_X < -3.5, classifying these objects as radio quiet.Comment: 18 pages, 15 figures, 5 table. Accepted for publication in A&

A deep 1.4 GHz survey of the J1030 equatorial field: A new window on radio source populations across cosmic time

We present deep L-Band observations of the equatorial field centered on the z = 6.3 Sloan Digital Sky Survey (SDSS) quasar (QSO). This field is rich of multiwavelength photometry and spectroscopy data, making it an ideal laboratory for galaxy evolution studies. Our observations reach a 1σ sensitivity of ~2.5 μJy at the center of the field. We extracted a catalog of 1489 radio sources down to a flux density of ~12.5 μJy (5σ) over a field of view of ~ 30′ diameter. We derived the source counts accounting for catalog reliability and completeness, and compared them with others available in the literature. Our source counts are among the deepest available so far, and, overall, are consistent with recent counts'determinations and models. They show a slight excess at flux densities ~50 μJy, possibly associated with the presence of known overdensities in the field. We detected for the first time in the radio band the SDSS J1030+0524 QSO (26 ± 5 μJy, 8σ significance level). For this object, we derived an optical radio loudness RO = 0.62±0.12, which makes it the most radio quiet among active galactic nuclei (AGN) discovered so far at z ≳ 6 and detected at radio wavelengths. We unveiled extended diffuse radio emission associated with the lobes of a bright Fanaroff-Riley type II (FRII) radio galaxy located close to the center of the J1030 field, which is likely to become the future brightest cluster galaxy of a protocluster at z = 1.7. The lobes'complex morphology, coupled with the presence of X-ray diffuse emission detected around the FRII galaxy lobes, may point toward an interaction between the radio jets and the external medium. We also investigated the relation between radio and X-ray luminosity for a sample of 243 X-ray-selected objects obtained from 500 ks Chandra observations of the same field, and spanning a wide redshift range (0 ≲ z ≲ 3). Focused on sources with a spectroscopic redshift and classification, we found that sources hosted by early-type galaxies and AGN follow log(LR)/log(LX) linear correlations with slopes of ~0.6 and ~0.8, respectively. This is interpreted as a likely signature of different efficiency in the accretion process. Finally, we found that most of these sources (≳87%) show a radio-to-X-ray radio loudness RX ≲ -3.5, classifying these objects as radio quiet

Near-infrared spectroscopy estimation of combined skeletal muscle oxidative capacity and O2 diffusion capacity in humans

The final steps of the O2 cascade during exercise depend on the product of the microvascular-tointramyocyte PO2 difference and muscle O2 diffusing capacity (DmO2). Non-invasive methods to determine DmO2 in humans are currently unavailable. Muscle oxygen uptake (mVO2) recovery rate constant (k), measured by near-infrared spectroscopy (NIRS) using intermittent arterial occlusions, is associated with muscle oxidative capacity in vivo. We reasoned that k would be limited by DmO2 when muscle oxygenation is low (kLOW), and hypothesized that: i) k in well-oxygenated muscle (kHIGH) is associated with maximal O2 flux in fiber bundles; and ii) Δk (kHIGH-kLOW) is associated with capillary density (CD). Vastus lateralis k was measured in 12 participants using NIRS after moderate exercise. The timing and duration of arterial occlusions were manipulated to maintain tissue saturation index (TSI) within a 10% range either below (LOW) or above (HIGH) half-maximal desaturation, assessed during sustained arterial occlusion. Maximal O2 flux in phosphorylating state was 37.7±10.6 pmol·s−1·mg−1 (~5.8 ml·min−1·100g−1). CD ranged 348 to 586 mm-2. kHIGH was greater than kLOW (3.15±0.45 vs 1.56±0.79 min-1, p\u3c0.001). Maximal O2 flux was correlated with kHIGH (r=0.80, p=0.002) but not kLOW (r=-0.10, p=0.755). Δk ranged -0.26 to -2.55 min-1, and correlated with CD (r=- 0.68, p=0.015). mVO2 k reflects muscle oxidative capacity only in well-oxygenated muscle. Δk, the difference in k between well- and poorly-oxygenated muscle, was associated with CD, a mediator of DmO2. Assessment of muscle k and Δk using NIRS provides a non-invasive window on muscle oxidative and O2 diffusing capacity

BULLKID: Monolithic array of particle absorbers sensed by Kinetic Inductance Detectors

We introduce BULLKID, an innovative phonon detector consisting of an array of dices acting as particle absorbers sensed by multiplexed Kinetic Inductance Detectors (KIDs). The dices are carved in a thick crystalline wafer and form a monolithic structure. The carvings leave a thin common disk intact in the wafer, acting both as holder for the dices and as substrate for the KID lithography. The prototype presented consists of an array of 64 dices of 5.4x5.4x5 mm$^3$ carved in a 3" diameter, 5 mm thick silicon wafer, with a common disk 0.5 mm thick hosting a 60 nm patterned aluminum layer. The resulting array is highly segmented but avoids the use of dedicated holding structures for each unit. Despite the fact that the uniformity of the KID electrical response across the array needs optimization, the operation of 8 units with similar features shows, on average, a baseline energy resolution of $26\pm7$ eV. This makes it a suitable detector for low-energy processes such as direct interactions of dark matter and coherent elastic neutrino-nucleus scattering