1,022 research outputs found
Writing the Self-at-War: World War I Popular Writings as \u201cTechnologies of the Self\u201d
Based on the analysis of more than 150 diaries and memoirs, this article highlights the rhetorical strategies used to define the self and shape the idea of war that characterized a specific peasant community, the Italian-speaking soldiers from the Trentino region that fought for Austria-Hungary in World War I. Through this case study the essay discusses how the Foucauldian notion of “technology of the self” can be applied to the study of war testimonies and to the historiographical debate on the nature of World War I “war culture”. By looking at the texts not in their message but in their form and in their function for the authors the study proposes a methodology to interpret sources that have been often deemed too repetitive and hermetic to be part of a systematic historical analysis.
Marine Heatwaves in the Chesapeake Bay
Prolonged events of anomalously warm sea water temperature, or marine heatwaves (MHWs), have major detrimental effects to marine ecosystems and the world\u27s economy. While frequency, duration and intensity of MHWs have been observed to increase in the global oceans, little is known about their potential occurrence and variability in estuarine systems due to limited data in these environments. In the present study we analyzed a novel data set with over three decades of continuous in situ temperature records to investigate MHWs in the largest and most productive estuary in the US: the Chesapeake Bay. MHWs occurred on average twice per year and lasted 11 days, resulting in 22 MHW days per year in the bay. Average intensities of MHWs were 3°C, with maximum peaks varying between 6 and 8°C, and yearly cumulative intensities of 72°C × days on average. Large co-occurrence of MHW events was observed between different regions of the bay (50–65%), and also between Chesapeake Bay and the Mid-Atlantic Bight (40–50%). These large co-occurrences, with relatively short lags (2–5 days), suggest that coherent large-scale air-sea heat flux is the dominant driver of MHWs in this region. MHWs were also linked to large-scale climate modes of variability: enhancement of MHW days in the Upper Bay were associated with the positive phase of Niño 1+2, while enhancement and suppression of MHW days in both the Mid and Lower Bay were associated with positive and negative phases of North Atlantic Oscillation, respectively. Finally, as a result of long-term warming of the Chesapeake Bay, significant trends were detected for MHW frequency, MHW days and yearly cumulative intensity. If these trends persist, by the end of the century the Chesapeake Bay will reach a semi-permanent MHW state, when extreme temperatures will be present over half of the year, and thus could have devastating impacts to the bay ecosystem, exacerbating eutrophication, increasing the severity of hypoxic events, killing benthic communities, causing shifts in species composition and decline in important commercial fishery species. Improving our basic understanding of MHWs in estuarine regions is necessary for their future predictability and to guide management decisions in these valuable environments
CFD Code Validation against Stratified Air-Water Flow Experimental Data
Pressurized thermal shock (PTS) modelling has been identified as one of the most important industrial needs related to nuclear reactor safety. A severe PTS scenario limiting the reactor pressure vessel (RPV) lifetime is the cold water emergency core cooling (ECC) injection into the cold leg during a loss of coolant accident (LOCA). Since it represents a big challenge for numerical simulations, this scenario was selected within the European Platform for Nuclear Reactor Simulations (NURESIM) Integrated Project as a reference two-phase problem for computational fluid dynamics (CFDs) code validation. This paper presents a CFD analysis of a stratified air-water flow experimental investigation performed at the Institut de MĂ©canique des Fluides de Toulouse in 1985, which shares some common physical features with the ECC injection in PWR cold leg. Numerical simulations have been carried out with two commercial codes (Fluent and Ansys CFX), and a research code (NEPTUNE CFD). The aim of this work, carried out at the University of Pisa within the NURESIM IP, is to validate the free surface flow model implemented in the codes against experimental data, and to perform code-to-code benchmarking. Obtained results suggest the relevance of three-dimensional effects and stress the importance of a suitable interface drag modelling
deterministic safety technology for rbmk reactors
The present paper deals with the description of the technical activities conducted within the TACIS Project R2.03/97, 2 EC Contract no. 30303, related to RBMK. The project activities are focused toward the setting-up of a chain of computational tools suitable for the analysis of transients expected in the RBMK nuclear power plant (NPP). The accident leading to the rupture of one pressure channel, with fuel melting or high temperature damage, creep and brittle failure of the pressure tube and of graphite bricks with possibility of rupture propagation, constitutes the reference scenario for the project. However, a series of expected scenarios has been selected to prove the capability of the individual codes or chains of code in simulating the envisaged phenomenology. The paper summarizes the activities performed at NIKIET in Moscow and at University of Pisa (UNIPI) in Pisa. A top-down approach is pursued in structuring the executive summary that includes the following sections: (i) the safety needed for the RBMK NPP, (ii) the roadmap, (iii) the adopted computational tools, (iv) key findings, (v) Emphasis is given to the multiple pressure tube rupture (MPTR) issue and the individual channel monitoring (ICM) proposal
Modeling changes in baleen whale seasonal abundance, timing of migration, and environmental variables to explain the sudden rise in entanglements in California
We document changes in the number of sightings and timing of humpback (Megaptera novaeangliae), blue (Balaenoptera musculus), and gray (Eschrichtius robustus) whale migratory phases in the vicinity of the Farallon Islands, California. We hypothesized that changes in the timing of migration off central California were driven by local oceanography, regional upwelling, and basin-scale climate conditions. Using 24 years of daily whale counts collected from Southeast Farallon Island, we developed negative binomial regression models to evaluate trends in local whale sightings over time. We then used linear models to assess trends in the timing of migration, and to identify potential environmental drivers. These drivers included local, regional and basin-scale patterns; the latter included the El Niño Southern Oscillation, the Pacific Decadal Oscillation, and the North Pacific Gyre Oscillation, which influence, wind-driven upwelling, and overall productivity in the California Current System. We then created a forecast model to predict the timing of migration. Humpback whale sightings significantly increased over the study period, but blue and gray whale counts did not, though there was variability across the time series. Date of breeding migration (departure) for all species showed little to no change, whereas date of migration towards feeding areas (arrival) occurred earlier for humpback and blue whales. Timing was significantly influenced by a mix of local oceanography, regional, and basin-scale climate variables. Earlier arrival time without concomitant earlier departure time results in longer periods when blue and humpback whales are at risk of entanglement in the Gulf of the Farallones. We maintain that these changes have increased whale exposure to pot and trap fishery gear off the central California coast during the spring, elevating the risk of entanglements. Humpback entanglement rates were significantly associated with increased counts and early arrival in central California. Actions to decrease the temporal overlap between whales and pot/trap fishing gear, particularly when whales arrive earlier in warm water years, would likely decrease the risk of entanglements
Grotta Romanelli (Southern Italy, Apulia). Legacies and issues in excavating a key site for the Pleistocene of the Mediterranean
Grotta Romanelli, located on the Adriatic coast of southern Apulia (Italy), is considered a key site for the Mediterranean Pleistocene for its archaeological and palaeontological contents. The site, discovered in 1874, was re-evaluated only in 1900, when P. E. Stasi realised that it contained the first evidence of the Palaeolithic in Italy. Starting in 1914, G. A. Blanc led a pioneering excavation campaign, for the first-time using scientific methods applied to systematic palaeontological and stratigraphical studies. Blanc proposed a stratigraphic framework for the cave. Different dating methods (C-14 and U/Th) were used to temporally constrain the deposits. The extensive studies of the cave and its contents were mostly published in journals with limited distribution and access, until the end of the 1970s, when the site became forgotten. In 2015, with the permission of the authorities, a new excavation campaign began, led by a team from Sapienza University of Rome in collaboration with IGAG CNR and other research institutions. The research team had to deal with the consequences of more than 40 years of inactivity in the field and the combined effect of erosion and legal, as well as illegal, excavations. In this paper, we provide a database of all the information published during the first 70 years of excavations and highlight the outstanding problems and contradictions between the chronological and geomorphological evidence, the features of the faunal assemblages and the limestone artefacts
Spreading and accumulation of river-borne sediments in the coastal ocean after the environmental disaster at the Doce River in Brazil
This study is focused on the fate of a large volume of mine slurry discharged from the Doce River (DR) to the coastal ocean after the worst environmental disaster in Brazilian which occurred in November 2015. We used Eulerian (ROMS) and Lagrangian (STRiPE) numerical models, as well as satellite remote sensing data, to study the spreading and seafloor accumulation of fine river-borne sediments during the initial six months following the disaster. We show that the regions of intense sediment accumulation were determined by spreading patterns of the surface-advected DR plume. The river discharge rate governed the plume surface area, while its position depended on local wind forcing conditions. The spreading of sediments carried by the DR plume was dominated by southward transport caused by prevailing upwelling-favorable northeasterly winds during the study period. Under high discharge conditions, river-borne sediments were transported over 100 km southward from the DR mouth and reached the outer shelf. In contrast, sediments were arrested near the mouth during drought periods and remained on the inner shelf. As a result, fine river-borne sediments accumulated on the seafloor, mainly in the large shallow shelf area southward from the DR mouth. Conversely, only a small fraction of residue was deposited northward. Thus, the Environmental Protection Area (EPA) of Costa das Algas, located 40 km southward from the DR, potentially exhibited more susceptibility to sediment arrival. On the other hand, their influence on Abrolhos Marine National Park, located 200 km northeastward from the DR mouth, was presumably minimal
New antimicrobials based on the adarotene scaffold with activity against multi-drug resistant staphylococcus aureus and vancomycin-resistant enterococcus
The global increase in infections by multi-drug resistant (MDR) pathogens is severely impacting our ability to successfully treat common infections. Herein, we report the antibacterial activity against S. aureus and E. faecalis (including some MDR strains) of a panel of adarotene-related synthetic retinoids. In many cases, these compounds showed, together with favorable MICs, a detectable bactericidal effect. We found that the pattern of substitution on adarotene could be modulated to obtain selectivity for antibacterial over the known anticancer activity of these compounds. NMR experiments allowed us to define the interaction between adarotene and a model of microorganism membrane. Biological assessment confirmed that the scaffold of adarotene is promising for further developments of non-toxic antimicrobials active on MDR strains
Geochemical investigation of a sediment core from the Trajan basin at Portus, the harbor of ancient Rome
International audiencea journal published by Elsevier. The attached copy is furnished to the author for internal non-commercial research and education use, including for instruction at the authors institution and sharing with colleagues. Other uses, including reproduction and distribution, or selling or licensing copies, or posting to personal, institutional or third party websites are prohibited. In most cases authors are permitted to post their version of the article (e.g. in Word or Tex form) to their personal website or institutional repository. Authors requiring further information regarding Elsevier's archiving and manuscript policies are encouraged to visit: a b s t r a c t From the 1st century AD and for the duration of the Roman Empire, the Portus complex was the main harbor of Rome. Its location on the Tiber delta next to the Tyrrhenian Sea produced rapid environmental changes that, together with historical vicissitudes, largely determined the fate of the harbor. We have assembled data on the mineralogy, sedimentology, geochemistry, and ostracod populations of a sediment core drilled in the access channel of the hexagonal basin of Trajan, with the expectation that such a combined data set will shed new light on how the connections of the inland Trajan basin with the Tiber river, the earlier Claudius harbor on the nearby shoreline, and the sea evolved through the centuries. The data define four distinct periods which geochemistry characterizes by different conditions of salinity and oxygenation. These in turn can be related to historical periods and events by means of 1
Effects of Acetyl-L-Carnitine on Oxidative Stress in Amyotrophic Lateral Sclerosis Patients: Evaluation on Plasma Markers and Members of the Neurovascular Unit
Oxidative stress, the alteration of mitochondrial function, and the neurovascular unit (NVU), play a role in Amyotrophic Lateral Sclerosis (ALS) pathogenesis. We aimed to demonstrate the changes in the plasma redox system and nitric oxide (NO) in 32 new ALS-diagnosed patients in treatment with Acetyl-L-Carnitine (ALCAR) compared to healthy controls. We also evaluated the effects of plasma on human umbilical cord-derived endothelial vascular cells (HUVEC) and astrocytes. The analyses were performed at the baseline (T0), after three months (T1), and after six months (T2). In ALS patients at T0/T1, the plasma markers of lipid peroxidation, thiobarbituric acid reactive substances (TBARS) and 4-hydroxy nonenal (4-HNE) were higher, whereas the antioxidants, glutathione (GSH) and the glutathione peroxidase (GPx) activity were lower than in healthy controls. At T2, plasma TBARS and 4-HNE decreased, whereas plasma GSH and the GPx activity increased in ALS patients. As regards NO, the plasma levels were firmly lower at T0–T2 than those of healthy controls. Cell viability, and mitochondrial membrane potential in HUVEC/astrocytes treated with the plasma of ALS patients at T0–T2 were reduced, while the oxidant release increased. Those results, which confirmed the fundamental role of oxidative stress, mitochondrial function, and of the NVU in ALS pathogenesis, can have a double meaning, acting as disease markers at baseline and potential markers of drug effects in clinical practice and during clinical trial
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