Supporting gender-neutral writing for German language with NLP techniques

Diese Arbeit beschäftigt sich mit der Frage, wie Verfasserinnen und Verfasser von Texten maschinell bei der Umsetzung eines geschlechtergerechten Sprachgebrauchs unterstützt werden können. Zu einem solchen geschlechtergerechten Sprachgebrauch in der deutschen Sprache gehört insbesondere die Vermeidung des generischen Maskulinums. Für diese Aufgabe der Vermeidung generischen Maskulinums soll ein System mittels der Verfahren der Computerlinguistik entwickelt werden, wel ches Vorkommen identifizieren und Korrekturvorschläge für diese erstellen kann. Ergänzend soll die Entwicklung einer Anwendung vorgestellt werden, die Anwenderinnen und Anwender eine grafische Oberfläche zur Korrektur ihrer Texte mit dem beschriebenen System bereitstellt. Im Rahmen einer Evaluation des Systems werden die Genauigkeit untersucht und Verbesserungsmöglichkeiten herausgearbeitet. Darüber hinaus werden auch andere Aspekte einer geschlechtergerechten Sprache in Bezug auf maschinelle Unterstützungsmöglichkeiten diskutiert.This work deals with the question of how to support authors of texts automatically in the use of gender-neutral language. The avoidance of the so called generisches Maskulinum is an important part of a gender-neutral use of the german language. For this task of avoiding the generisches Maskulinum, by using methods of natural language processing a system will be developed, that can identify such occurrences and generates suggestions for correction of those occurences. In addition, an application will be developed, that allows users to correct their texts with a graphical interface using the developed system. The accuracy of said system will be examined and opportunities for improvement discussed. In addition, other aspects of gender-neutral use of the german language, in relation to machine support possibilities, will be discussed

What is the role of the corpus callosum in intermanual transfer of motor skills? A study of three cases with callosal pathology

Intermanual transfer for a skilled motor task was studied in two patients with total callosal agenesis, and one with an acquired partial callosal lesion and clinical evidence for disturbed transfer of motor signals. Patients had to draw meaningless figures with one upper extremity (original learning, OL) and to reproduce their mirror-reversals thereafter with the other side (transfer learning, TL). Both directions of intermanual transfer were tested in two conditions, that is, between either proximal or distal muscle groups. Transfer was evaluated by comparing OL and TL performance at the same effector. The main variable of interest was movement time during the first eight trials of OL and TL. All three patients displayed a significant benefit for transfer from the dominant to the non-dominant hand but not vice versa during proximal motor activity. When compared with the performance of healthy subjects tested in almost identical conditions in a previously reported study, the proximal transfer behavior was found to be similar for all patients and the normal group. Although patients exhibited no significant benefit for distal transfer, their non-dominant-to-dominant distal transfer was above the normal range. The similar transfer pattern of the patients and healthy subjects when using proximal musculature suggests that proximal transfer may be subserved by identical extracallosal pathways, most probably by the ipsilaterally descending motor systems. Since non-dominant-to-dominant distal transfer was found to be disadvantageous in healthy subjects, the patients' relative superiority in this condition may reflect missing callosal influences of an inhibitory natur

A pure case of Gerstmann syndrome with a subangular lesion

The four symptoms composing Gerstmann's syndrome were postulated to result from a common cognitive denominator (Grundstörung) by Gerstmann himself. He suggested that it is a disorder of the body schema restricted to the hand and fingers. The existence of a Grundstörung has since been contested. Here we suggest that a common psychoneurological factor does exist, but should be related to transformations of mental images rather than to the body schema. A patient (H.P.) was studied, who presented the four symptoms of Gerstmann's syndrome in the absence of any other neuropsychological disorders. MRI showed a focal ischaemic lesion, situated subcortically in the inferior part of the left angular gyrus and reaching the superior posterior region of T1. The cortical layers were spared and the lesion was seen to extend to the callosal fibres. On the basis of an extensive cognitive investigation, language, praxis, memory and intelligence disorders were excluded. The four remaining symptoms (finger agnosia, agraphia, right-left disorientation and dyscalculia) were investigated thoroughly with the aim of determining any characteristics that they might share. Detailed analyses of the tetrad showed that the impairment was consistently attributable to disorders of a spatial nature. Furthermore, cognitive tests necessitating mental rotation were equally shown to be impaired, confirming the essentially visuospatial origin of the disturbance. In the light of this report, the common cognitive denominator is hypothesized to be an impairment in mental manipulation of images and not in body schem

Challenges in Securities Markets Regulation: Investor Protection and Corporate Governance

On November 14th, 2014, SUERF – The European Money and Finance Forum – and CNMV, Comisión Nacional del Mercado de Valores – the Spanish Authority for supervision of securities markets – jointly organized a conference in Madrid: Challenges in Securities Markets Regulation: Investor Protection and Corporate Governance. The conference was part of the activities arranged to celebrate the 25th anniversary of the creation of the CNMV. The present SUERF Study includes a selection of papers based on the authors’ contributions to the Madrid conference

Hepatitis B assays in serum, plasma and whole blood on filter paper

BACKGROUND: Screening and determining the immune status of individuals for hepatitis B is usually done by detecting hepatitis B surface antigen (HBsAg) and hepatitis B surface antigen-specific antibodies (HBsAb). In some countries with the highest viral burden, performing these assays is currently impractical. This paper explores the use of filter paper as a blood specimen transport medium. METHODS: Samples, chosen from routine clinical laboratory pool, were applied and dried onto filter paper. Eluates, from the paper samples, were analyzed as routine clinical specimens on ADVIA Centaur 5634® immunoassay analyzers using the standard HBsAg and HBsAb kits. Dried blood samples were subjected to a range of environmental conditions in order to assess stability. RESULTS: After drying and elution the assays showed linearity and precision comparable to clinical assays performed on fresh serum. Elutions at various times during a 149 day incubation period showed very little variability in the Index numbers. All analytes were temperature stable except for a decrease in the HBsAg signal at 42°C. CONCLUSIONS: Filter paper is an acceptable storage and transport medium for serum to be used in the detection of hepatitis B markers if atmospheric variability can be controlled. HBsAg, HBsAb and HBcAb are all stable for at least five months under storage conditions below room temperature. Drying specimens, particularly serum, on filter paper at remote locations, offers a reasonable solution to the problem of hepatitis surveillance in underdeveloped regions, although some attempt at temperature control might be desirable

Radial Velocity Studies of Close Binary Stars.XIII

Radial-velocity measurements and sine-curve fits to the orbital radial velocity variations are presented for ten close binary systems: EG Cep,V1191 Cyg, V1003 Her, BD+7_3142, V357 Peg, V407 Peg, V1123 Tau, V1128 Tau, HH UMa, and PY Vir. While most of the studied eclipsing systems are contact binaries, EG Cep is a detached or a semi-detached double-lined binary and V1003 Her is a close binary of an uncertain type seen at a very low inclination angle. We discovered two previously unknown triple systems, BD+7_3142 and PY Vir, both with late spectral-type (K2V) binaries. Of interest is the low-mass ratio (q = 0.106) close binary V1191 Cyg showing an extremely fast period increase; the system has a very short period for its spectral type and shows a W-type light curve, a feature rather unexpected for such a low mass-ratio system.Comment: Accepted by AJ. 19 pages including 5 figure

Routine diagnostics for neural antibodies, clinical correlates, treatment and functional outcome

Abstract Objective To determine frequencies, interlaboratory reproducibility, clinical ratings, and prognostic implications of neural antibodies in a routine laboratory setting in patients with suspected neuropsychiatric autoimmune conditions. Methods Earliest available samples from 10,919 patients were tested for a broad panel of neural antibodies. Sera that reacted with leucine-rich glioma-inactivated protein 1 (LGI1), contactin-associated protein-2 (CASPR2), or the voltage-gated potassium channel (VGKC) complex were retested for LGI1 and CASPR2 antibodies by another laboratory. Physicians in charge of patients with positive antibody results retrospectively reported on clinical, treatment, and outcome parameters. Results Positive results were obtained for 576 patients (5.3%). Median disease duration was 6 months (interquartile range 0.6–46 months). In most patients, antibodies were detected both in CSF and serum. However, in 16 (28%) patients with N-methyl-d-aspartate receptor (NMDAR) antibodies, this diagnosis could be made only in cerebrospinal fluid (CSF). The two laboratories agreed largely on LGI1 and CASPR2 antibody diagnoses (κ = 0.95). The clinicians (413 responses, 71.7%) rated two-thirds of the antibody-positive patients as autoimmune. Antibodies against the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR), NMDAR (CSF or high serum titer), γ-aminobutyric acid-B receptor (GABABR), and LGI1 had ≥ 90% positive ratings, whereas antibodies against the glycine receptor, VGKC complex, or otherwise unspecified neuropil had ≤ 40% positive ratings. Of the patients with surface antibodies, 64% improved after ≥ 3 months, mostly with ≥ 1 immunotherapy intervention. Conclusions This novel approach starting from routine diagnostics in a dedicated laboratory provides reliable and useful results with therapeutic implications. Counseling should consider clinical presentation, demographic features, and antibody titers of the individual patient