Degenerative Myelopathy in the German Shepherd

Older large breed dogs, primarily of the German Shepherd type, may be presented with progressive ataxic spastic paresis. There seems to be no sex predominance. The lesion found on necropsy is diffuse degeneration of spinal cord myelin and axons in all fiber tracts, most extensive and in the mid-thoracic region, but not associated with intervertebral disc herniation, spondylosis, or osseous metaplasia of the dura. The condition is thought to be primary spinal cord degeneration of unknown cause

Degenerative Myelopathy in the German Shepherd

Older large breed dogs, primarily of the German Shepherd type, may be presented with progressive ataxic spastic paresis. There seems to be no sex predominance. The lesion found on necropsy is diffuse degeneration of spinal cord myelin and axons in all fiber tracts, most extensive and in the mid-thoracic region, but not associated with intervertebral disc herniation, spondylosis, or osseous metaplasia of the dura. The condition is thought to be primary spinal cord degeneration of unknown cause.</p

Libraries in a Bind: Practical Solutions and Human Responses to a Weeding Mandate

Many university libraries are currently engaged in major weeding projects as they reduce their print book collections to make room for new space configurations to accommodate emerging library trends such as makerspaces and transitioning toward a predominately e‐book collection.To address such a deselection project effectively requires both practical solutions and tact in dealing with faculty who seriously value their collections of print books. Librarians from two universities will share practical approaches to managing a large weeding project and for dealing diplomatically with book users affected. Representatives for deselection project services will also offer insights into their logistic support for handling weeding projects. Ample time will be provided for discussion where collection librarians can candidly discuss both the practical problems and user concerns faced when sandwiched between the demands of a major weeding project and the needs of faculty and students in book‐reliant disciplines

PET-guided breast biopsy.

Molecular imaging, using positron emission tomography (PET), has become an integral step in the evaluation of many patients with malignancy. However, its use in patients with breast cancer has been limited by the lower levels of (18) F-fluorodeoxyglucose (FDG) uptake in some breast malignancies compared to other cancers, the small size of many breast cancers, and the need for biopsy under PET guidance. High-resolution breast PET, or positron emission mammography (PEM), with biopsy guidance software, now addresses these issues. We report a prospective, multicenter study designed to test the efficacy and safety of PEM biopsy guidance software in women with FDG-avid breast lesions worrisome for malignancy. The intervention chosen was vacuum-assisted core biopsy. Nineteen subjects underwent a total of 24 PEM-guided biopsies. All lesions were successfully targeted and sampled as determined by post-biopsy image scan evaluation, specimen imaging, and pathologic concordance. Invasive cancer was identified in 13 of 24 lesions (54%), while four (17%) were high-risk lesions and three of these were upgraded to malignancy at excision. No serious adverse events occurred and all patients found the procedure to cause only minimal to mild discomfort. High-resolution PEM-guided breast biopsy is both safe and effective for the sampling of PET-depicted breast lesions