Oversexualization in Primitivism

This essay examines how Primitivist artwork of the late 1800s and early 1900s by Matisse, Gauguin, and Picasso oversexualized colonized women. White European male artists viewed colonized women as the ‘other’ through a biased racialized and gendered lens. Fatimah Tobing Roby’s theory of Ethnographic Spectacle and Kimberlé Crenshaw’s theory of intersectionality are evident in these Primitivist works. Through a deeply rooted colonial mindset, European male artists exploited the image of colonized women because they are considered outside of history and unevolved. Colonized women experienced this unfair treatment due to their unique intersectional position of gender and race, as well as the European fascination with the ‘other.’ Primitivist artworks depict colonized women as a projection of sexual fantasies because their position deemed outside of history places them outside of moral consequence by European male artists

Putting development first: concerns about a Pacific free trade agreement

No abstract availabl

Developing Research-Led Teaching: Two Cases of Practical Data Reuse in the Classroom

Research-led teaching is an area that has gained attention and prominence within higher education. This article reviews two teaching resources developed from archived research data and demonstrates how this type of data reuse helps teachers establish a clear connection between research and teaching. The two teaching resources, developed by the authors in their time working at the UK Data Service, were created for use in higher education, and use Annette Lawson’s 1980s study of adultery and Stanley Cohen’s 1960s study of Mods and Rockers. The authors describe the resources in detail, explain how and why the content was developed, and explore the potential value that preserved real-world research data can have when using research to teach. The reviews of these resources point to the great possibilities for future development of teaching resources using archived data to support a range of teaching modules, from methods to topical undergraduate courses, as well as demonstrate the value of archived data and documentation for research practices

Management Practices for An Art-Based Community Program: How to Design a 100 Year Company!

Over the past six years, Molloy College students and faculty have presented at the Northeast Business & Economics Association Conference the outcomes of a pedagogical process that allows students to demonstrate evidence of learning. This paper reports on the student consulting work presented to the leadership team and the Board of Directors of a local not-for-profit organization. The consulting problem identified by the leaders of the organization is that ‘they are new to running a corporation’. The Officers are not traditional managers. The work of these organizational leaders had been focused on the corporation’s cause. Therefore, these organizational leaders need to establish all of the management practices to run this business. The consulting solution developed by the capstone student consultants included a 4-tier plan, which focused on (1) the organizational structure, (2) financial structure, (3) fundraising strategies, and (4) marketing/branding plan. There are two goals for writing this paper. The first is to tell the story of Backyard Players and Friends Inc. and the business plan that offered this organization, not just consulting advice, but an executable turnkey executable set of solutions focused directly on the real-world problem. The second goal for this paper is to demonstrate one college’s educational strategy to help graduate students develop the skills and knowledge needed to lead at an advanced level, and to develop a disposition toward social responsibility and ethical leadership

On Stage Māori-Medium ITE: Listening to Students’ Voices

Māori-medium initial teacher education (ITE) is a small but highly important group ‘on stage’ in te ao Māori and New Zealand education. While education plays a major role in Māori language revitalisation, Māori language is also pivotal to Māori education if the aspiration ‘to live as Māori’ (Durie, 2001) is to be fulfilled. Māori-medium teachers are critical to the success of learners and their whānau who select a Māori-medium pathway and who can make a meaningful difference to the educational outcomes of Māori (Hōhepa, Hāwea, Tamatea, & Heaton, 2014). This article draws on the students’ voices in a two-year research project that centered on the development of a teaching and learning initiative within one Māori-medium ITE programme. Building on previous work by Hōhepa et al. (2014), this study adds another layer of students’ voices to understand more clearly language related issues and student experiences in Māori-medium ITE programmes. The article presents some of the complexities associated with Māori language regeneration facing students of Māori-medium ITE, with the understanding that whatever appears on the stage is always part of a greater narrative behind the scenes

Researching Attitudes Towards Peace and Conflict and Darfur: An Analysis of a Research Initiative From February 2007 – October 2008

The Researching Attitudes towards Peace and Conflict in Darfur project seeks to inform the ongoing peace process in Darfur by providing the various institutions involved in the mediation efforts with a deeper understanding of Darfurians’ perspectives on the causes of the conflict, its impact on their lives, and the role of the international community in its resolution. The project was initiated at the request of Albany Associates (www.albanyassociates.com), which was contracted by the UK’s Department for International Development in 2006 to engage in communication about the Darfur peace process among the population of Darfur and other key stakeholders on behalf of the African Union Mission in Sudan (AMIS) and later United Nations-African Union Mission in Darfur (UNAMID). The project is a partnership of the Center for Global Communication Studies (Annenberg School for Communication, University of Pennsylvania) and the Stanhope Centre for Communications Policy Research, and is funded by contributions from the Dutch Ministry for Development Cooperation and the Canadian Department of Foreign Affairs and International Trade. The guiding premise of the project is that complex, seemingly intractable conflicts cannot be effectively resolved without taking into account the positions and opinions of those most directly affected

Clinical and serological features of systemic sclerosis in a multicenter African American cohort: Analysis of the genome research in African American scleroderma patients clinical database

Racial differences exist in the severity of systemic sclerosis (SSc). To enhance our knowledge about SSc in African Americans, we established a comprehensive clinical database from the largest multicenter cohort of African American SSc patients assembled to date (the Genome Research in African American Scleroderma Patients (GRASP) cohort). African American SSc patients were enrolled retrospectively and prospectively over a 30-year period (1987–2016), from 18 academic centers throughout the United States. The cross-sectional prevalence of sociodemographic, clinical, and serological features was evaluated. Factors associated with clinically significant manifestations of SSc were assessed using multivariate logistic regression analyses. The study population included a total of 1009 African American SSc patients, comprised of 84% women. In total, 945 (94%) patients met the 2013 American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) classification criteria for SSc, with the remaining 64 (6%) meeting the 1980 ACR or CREST (calcinosis, Raynaud\u27s phenomenon, esophageal dysmotility, sclerodactyly, telangiectasia) criteria. While 43% were actively employed, 33% required disability support. The majority (57%) had the more severe diffuse subtype and a young age at symptom onset (39.1 ± 13.7 years), in marked contrast to that reported in cohorts of predominantly European ancestry. Also, 1 in 10 patients had a severe Medsger cardiac score of 4. Pulmonary fibrosis evident on computed tomography (CT) chest was present in 43% of patients and was significantly associated with anti-topoisomerase I positivity. 38% of patients with CT evidence of pulmonary fibrosis had a severe restrictive ventilator defect, forced vital capacity (FVC) ≤50% predicted. A significant association was noted between longer disease duration and higher odds of pulmonary hypertension, telangiectasia, and calcinosis. The prevalence of potentially fatal scleroderma renal crisis was 7%, 3.5 times higher than the 2% prevalence reported in the European League Against Rheumatism Scleroderma Trials and Research (EUSTAR) cohort. Our study emphasizes the unique and severe disease burden of SSc in African Americans compared to those of European ancestry

Mapping a Quantitative Trait Locus (QTL) conferring pyrethroid resistance in the African malaria vector Anopheles funestus

BACKGROUND: Pyrethroid resistance in Anopheles funestus populations has led to an increase in malaria transmission in southern Africa. Resistance has been attributed to elevated activities of cytochrome P450s but the molecular basis underlying this metabolic resistance is unknown. Microsatellite and SNP markers were used to construct a linkage map and to detect a quantitative trait locus (QTL) associated with pyrethroid resistance in the FUMOZ-R strain of An. funestus from Mozambique. RESULTS: By genotyping 349 F(2 )individuals from 11 independent families, a single major QTL, rp1, at the telomeric end of chromosome 2R was identified. The rp1 QTL appears to present a major effect since it accounts for more than 60% of the variance in susceptibility to permethrin. This QTL has a strong additive genetic effect with respect to susceptibility. Candidate genes associated with pyrethroid resistance in other species were physically mapped to An. funestus polytene chromosomes. This showed that rp1 is genetically linked to a cluster of CYP6 cytochrome P450 genes located on division 9 of chromosome 2R and confirmed earlier reports that pyrethroid resistance in this strain is not associated with target site mutations (knockdown resistance). CONCLUSION: We hypothesize that one or more of these CYP6 P450s clustered on chromosome 2R confers pyrethroid resistance in the FUMOZ-R strain of An. funestus

Predicting success of oligomerized pool engineering (OPEN) for zinc finger target site sequences

<p>Abstract</p> <p>Background</p> <p>Precise and efficient methods for gene targeting are critical for detailed functional analysis of genomes and regulatory networks and for potentially improving the efficacy and safety of gene therapies. Oligomerized Pool ENgineering (OPEN) is a recently developed method for engineering C2H2 zinc finger proteins (ZFPs) designed to bind specific DNA sequences with high affinity and specificity <it>in vivo</it>. Because generation of ZFPs using OPEN requires considerable effort, a computational method for identifying the sites in any given gene that are most likely to be successfully targeted by this method is desirable.</p> <p>Results</p> <p>Analysis of the base composition of experimentally validated ZFP target sites identified important constraints on the DNA sequence space that can be effectively targeted using OPEN. Using alternate encodings to represent ZFP target sites, we implemented Naïve Bayes and Support Vector Machine classifiers capable of distinguishing "active" targets, i.e., ZFP binding sites that can be targeted with a high rate of success, from those that are "inactive" or poor targets for ZFPs generated using current OPEN technologies. When evaluated using leave-one-out cross-validation on a dataset of 135 experimentally validated ZFP target sites, the best Naïve Bayes classifier, designated ZiFOpT, achieved overall accuracy of 87% and specificity⁺of 90%, with an ROC AUC of 0.89. When challenged with a completely independent test set of 140 newly validated ZFP target sites, ZiFOpT performance was comparable in terms of overall accuracy (88%) and specificity⁺(92%), but with reduced ROC AUC (0.77). Users can rank potentially active ZFP target sites using a confidence score derived from the posterior probability returned by ZiFOpT.</p> <p>Conclusion</p> <p>ZiFOpT, a machine learning classifier trained to identify DNA sequences amenable for targeting by OPEN-generated zinc finger arrays, can guide users to target sites that are most likely to function successfully <it>in vivo</it>, substantially reducing the experimental effort required. ZiFOpT is freely available and incorporated in the Zinc Finger Targeter web server (<url>http://bindr.gdcb.iastate.edu/ZiFiT</url>).</p