389 research outputs found

    Networks in Nigeria: A pilot study on network characteristics and their relation with life satisfaction in a Nigerian sample

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    Social relationships are a central determinant of life satisfaction. The collectivity of individual social relationships form a social network. This study examines such networks in a Nigerian sample (N = 108). Network size, proportions of positive and negative relationships within those networks, and structural characteristics (e.g., network centrality) were assessed. Furthermore, network characteristics were examined concerning their association with life satisfaction. Results indicate differential relations of network characteristics with life satisfaction. Results are discussed in terms of (1) cross-cultural assessment of network characteristics, (2) life satisfaction as related to social structural characteristics, and (3) differential associations between network types and different aspects of life satisfaction

    Quo vadis CPS? Brief answers to big questions

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    Research on complex problem solving (CPS) has reached a stage where certain standards have been achieved, whereas the future development is quite ambiguous. In this situation, the editors of the Journal of Dynamic Decision Making asked a number of representative authors to share their point of view with respect to seven questions about the relevance of (complex) problem solving as a research area, about the contribution of laboratory-based CPS research to solving real life problems, about the roles of knowledge, strategies, and intuition in CPS, and about the existence of expertise in CPS

    Naturwissenschaften in der Erwachsenenbildung: was, wie und wozu vermitteln?

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    Vor dem Hintergrund einer seit mehr als zehn Jahren andauernden Debatte um Möglichkeiten für eine Verbesserung der naturwissenschaftlichen Bildung in Deutschland zielen die im Folgenden präsentierten Überlegungen darauf ab, den Beitrag der organisierten Erwachsenenbildung für eine Veränderung des Status Quo zu umreißen. Ausgegangen wird von der quantitativen Randständigkeit des Angebots, bevor der Blick auf didaktische Arrangements und Konzepte gerichtet wird. Diese werden auf der Grundlage einer empirischen Studie -mit Blick auf Ziele, Inhalte, Arbeitsformen und Adressaten naturwissenschaftlicher Angebote in der Erwachsenenbildung- analysiert und mit Vermittlungsangeboten in so genannten informellen Lernumgebungen, u.a. Medien, Science Centern, Museen, kontrastiert. Abschließend folgen Überlegungen zu den Konsequenzen, die sich aus der bestehenden Praxis für die verbreitete Forderung nach einer naturwissenschaftlichen Literalität ergeben, insbesondere im Blick auf Forschungsbedarfe in der Erwachsenenbildung

    The antimicrobial effect of Octenidine-dihydrochloride coated polymer tracheotomy tubes on Staphylococcus aureus and Pseudomonas aeruginosa colonisation

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    <p>Abstract</p> <p>Background</p> <p>The surface of polymeric tracheotomy tubes is a favourable environment for biofilm formation and therefore represents a potential risk factor for the development of pneumonia after tracheotomy. The aim of this <it>in-vitro </it>study was to develop octenidine-dihydrochloride (OCT) coated polymer tracheotomy tubes and investigate any effects on <it>Staphylococcus (S.) aureus </it>and <it>Pseudomonas (P.) aeruginosa </it>colonization. Additionally the resistance of the OCT coating was tested using reprocessing procedures like brushing, rinsing and disinfection with glutaraldehyde</p> <p>Results</p> <p><it>Contamination with S. aureus</it>: Before any reprocessing, OCT coated tracheotomy tubes were colonized with 10<sup>3 </sup>cfu/ml and uncoated tracheotomy tubes with 10<sup>5 </sup>cfu/ml (P = 0.045). After reprocessing, no differences in bacterial concentration between modified and conventional tubes were observed.</p> <p><it>Contamination with P. aeruginosa</it>: Before reprocessing, OCT coated tubes were colonized with 10<sup>6 </sup>cfu/ml and uncoated tubes with 10<sup>7 </sup>cfu/ml (P = 0.006). After reprocessing, no significant differences were observed.</p> <p>Conclusion</p> <p>OCT coating initially inhibits <it>S. aureus </it>and <it>P. aeruginosa </it>colonisation on tracheotomy tubes. This effect, however, vanishes quickly after reprocessing of the tubes due to poor adhesive properties of the antimicrobial compound. Despite the known antimicrobial effect of OCT, its use for antimicrobial coating of tracheotomy tubes is limited unless methods are developed to allow sustained attachment to the tube.</p

    Learning to solve ill-defined statistics problems: does self-explanation quality mediate the worked example effect?

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    Extensive research has established that successful learning from an example is conditional on an important learning activity: self-explanation. Moreover, a model for learning from examples suggests that self-explanation quality mediates effects of examples on learning outcomes (Atkinson et al. in Rev Educ Res 70:181–214, 2000). We investigated self-explanation quality as mediator in a worked examples—problem-solving paradigm. We developed a coding scheme to assess self-explanation quality in the context of ill-defined statistics problems and analyzed self-explanation data of a study by Schwaighofer et al. (J Educ Psychol 108: 982–1000, 2016). Schwaighofer et al. (J Educ Psychol 108: 982–1000, 2016) investigated whether the worked example effect depends on prior knowledge, working memory capacity, shifting ability, and fluid intelligence. In our study, we included these variables to jointly explore mediating and moderating factors when individuals learn with worked examples versus through problem-solving. Seventy-four university students (mean age = 23.83, SD = 5.78) completed an open item pretest, self-explained while either studying worked examples or solving problems, and then completed a post-test. We used conditional process analysis to test whether the effect of worked examples on learning gains is mediated by self-explanation quality and whether any effect in the mediation model depends on the suggested moderators. We reproduced the interaction effects reported by Schwaighofer et al. (J Educ Psychol 108: 982–1000, 2016) but did not detect a mediation effect. This might indicate that worked examples are directly effective because they convey a solution strategy, which might be particularly important when learning to solve problems that have no algorithmic solution procedure

    Progressive Multiple Sequence Alignments from Triplets

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    Motivation: The quality of progressive sequence alignments strongly depends on the accuracy of the individual pairwise alignment steps since gaps that are introduced at one step cannot be removed at later aggregation steps. Adjacent insertions and deletions necessarily appear in arbitrary order in pairwise alignments and hence form an unavoidable source of errors. Idea: Here we present a modified variant of progressive sequence alignments that addresses both issues. Instead of pairwise alignments we use exact dynamic programming to align sequence or profile triples. This avoids a large fractions of the ambiguities arising in pairwise alignments. In the subsequent aggregation steps we follow the logic of the Neighbor-Net algorithm, which constructs a phylogenetic network by step-wisely replacing triples by pairs instead of combining pairs to singletons. To this end the three-way alignments are subdivided into two partial alignments, at which stage all-gap columns are naturally removed. This alleviates the “once a gap, always a gap” problem of progressive alignment procedures. Results: The three-way Neighbor-Net based alignment program aln3nn is shown to compare favorably on both protein sequences and nucleic acids sequences to other progressive alignment tools. In the latter case one easily can include scoring terms that consider secondary structure features. Overall, the quality of resulting alignments in general exceeds that of clustalw or other multiple alignments tools even though our software does not included heuristics for context dependent (mis)match scores
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