Deoxofluorination of graphite oxide with sulfur tetrafluoride

In this study, deoxofluorination of graphite oxide (GO) using sulfur tetrafluoride (SF₄) at a temperature below the decomposition temperature of GO (∼200 °C) was investigated for the first time with and without HF catalysis. At 25 °C, the reaction proceeds only at high SF₄ pressures (≥8 atm) when not catalyzed by HF and at 1 atm SF₄ under the catalysis of HF. The degree of fluorination increases at higher temperatures and SF₄ pressures. Hydroxy and carbonyl groups are replaced by fluorine following this reaction, and SF₄ and SOF₂ are introduced into the product, while the epoxy groups do not react. SF₄ and SOF₂ in the products are removed by washing with water. The obtained product is less hygroscopic than pristine GO owing to the hydrophobicity of the fluorine atom. The interlayer separation of the product is increased after deoxofluorination despite the smaller size of fluorine than the sizes of the oxygen-containing functional groups. When compared with direct fluorination using elemental fluorine, deoxofluorination using SF₄ has the advantages of high reactivity with hydroxy groups and the preservation of the carbon skeleton, and the reaction results in the formation of graphite oxyfluoride

Exploring 3P0^3P_0 Superfluid in Dilute Spin-Polarized Neutron Matter

We explore the theoretical possibility of $^3P_0$ neutron superfluid in dilute spin-polarized neutron matter, which may be relevant to the crust region of a magnetized neutron star. In such a dilute regime where the neutron Fermi energy is less than 1 MeV, the $^1S_0$ neutron superfluid can be suppressed by a strong magnetic field of the compact star. In the low-energy limit relevant for dilute neutron matter, the $^3P_0$ interaction is stronger than the $^3P_2$ one which is believed to induce the triplet superfluid in the core. We present the ground-state phase diagram of dilute neutron matter with respect to the magnetic field and numerically estimate the critical temperature of the $^3P_0$ neutron superfluid, which is found to exceed $10^7$ K.Comment: 6 pages, 3 figure

イ ジョウコウ ケッチョウ チョクチョウ ノ 3 チョウフクガン ニ タイシテ イッキテキ ニ フククウキョウカ シュジュツ オ シコウ シタ 1レイ

A ５１-years-old man was admitted with anemia. The upper gastrointestinal endoscopy revealed ０-IIa＋IIc lesion in the middle body of the stomach. The colonoscopy revealed type ３ lesion by Borrmann classification with advanced stenosis. Computed tomography of the abdomen revealed the tumor in the ascending colon. We diagnosed a synchronous gastric, ascending colon, and rectal cancer. After neoadjuvant chemotherapy, we performed the laparoscopic operation for the synchronous cancer. There were no remarkable complications due to the collaboration. Laparoscopic approach for synchronous triple cancer is feasible as safety and minimally invasive surgery

Mesh-Airtight-Preperitoneum : a simple method for confirming mesh placement in transabdominal preperitoneal repair of inguinal hernia

We devised a method for confirming the position of mesh placed during transabdominal preperitoneal repair (TAPP) of an inguinal hernia. The preperitoneum is sufficiently detached, and the mesh is fixed in place as usual. Before completely closing the peritoneum, pressure is applied from outside the body and inside the abdominal cavity to remove as much air as possible from the detached preperitoneum ; the peritoneum is then sutured using a V-LocTM closure device so that it does not constrict. By releasing the pressure all at once, the airtightness of the preperitoneum is maintained, and the position of the mesh can be observed through the translucent peritoneum. This method, called Mesh-Airtight-Preperitoneum (MAPP), could become widely used as a simple technique for confirming mesh position in TAPP

キョウセン ヒテイケイテキ カルチノイド ノ 1セツジョレイ

Background. Thymic carcinoids are rare disease to account for ２-４％ of anterior mediastinal tumors. So, the clinicopathologic characters are not known enough. Case. A ６７ years old man was followed up old myocardial infarction, and he was taken chest CT scan for evaluate coronary artery. It revealed three anterior mediastinal tumors and we diagnosed thymoma by needle biopsy. We treated by neoadjuvant chemotherapy（CAMP therapy）, but it was ineffective. We performed thoracoscopic thymothymomectomy, and the pathological diagnosis was thymic atypical carcinoid. He is free of clinically event recurrence one year and a half after treatment. Conclusions. When we found an anterior mediastinal tumor, and if the clinical course is usually different, we should consider the possibility of a thymic carcinoid

ACPA-negative RA consists of two genetically distinct subsets based on RF positivity in Japanese.

HLA-DRB1, especially the shared epitope (SE), is strongly associated with rheumatoid arthritis (RA). However, recent studies have shown that SE is at most weakly associated with RA without anti-citrullinated peptide/protein antibody (ACPA). We have recently reported that ACPA-negative RA is associated with specific HLA-DRB1 alleles and diplotypes. Here, we attempted to detect genetically different subsets of ACPA-negative RA by classifying ACPA-negative RA patients into two groups based on their positivity for rheumatoid factor (RF). HLA-DRB1 genotyping data for totally 954 ACPA-negative RA patients and 2,008 healthy individuals in two independent sets were used. HLA-DRB1 allele and diplotype frequencies were compared among the ACPA-negative RF-positive RA patients, ACPA-negative RF-negative RA patients, and controls in each set. Combined results were also analyzed. A similar analysis was performed in 685 ACPA-positive RA patients classified according to their RF positivity. As a result, HLA-DRB1*04:05 and *09:01 showed strong associations with ACPA-negative RF-positive RA in the combined analysis (p = 8.8×10(-6) and 0.0011, OR: 1.57 (1.28-1.91) and 1.37 (1.13-1.65), respectively). We also found that HLA-DR14 and the HLA-DR8 homozygote were associated with ACPA-negative RF-negative RA (p = 0.00022 and 0.00013, OR: 1.52 (1.21-1.89) and 3.08 (1.68-5.64), respectively). These association tendencies were found in each set. On the contrary, we could not detect any significant differences between ACPA-positive RA subsets. As a conclusion, ACPA-negative RA includes two genetically distinct subsets according to RF positivity in Japan, which display different associations with HLA-DRB1. ACPA-negative RF-positive RA is strongly associated with HLA-DRB1*04:05 and *09:01. ACPA-negative RF-negative RA is associated with DR14 and the HLA-DR8 homozygote