Antisynthetase syndrome: Pulmonary computed tomography findings of adult patients with antibodies to aminoacyl-tRNA synthetases

AbstractObjectivesTo describe the pulmonary CT findings in patients with anti-ARS-antibody-positive interstitial lung disease (anti-ARS-ILD)MethodsThe CT findings of 64 patients with anti-ARS-ILD were retrospectively reviewed. The images were retrospectively reviewed independently by 2 chest radiologists, and the final decision on the CT findings was made by a third chest radiologist.ResultsThere were 16 male and 48 female patients, aged 54.2±13.4 years. Sixteen patients had anti Jo-1, 24 had anti-EJ, 9 had anti-PL-7, 7 had anti-PL-12, 5 had anti-KS, and 3 had anti-OJ antibodies. Overall, 63 patients (98.4%) had CT findings predominantly in the lower lobe; 61 patients (95.3%) showed peripheral opacities, and 47 patients (73.4%) showed peribronchovascular opacities. Ground-glass attenuation, consolidation, and reticulation showed similar distribution patterns. Regarding detailed CT findings, 89.1% of patients had lower volume loss, 76.6% had interlobular septal thickening, and 67.2% had thickening of bronchovascular bundles. The final radiologic diagnoses were as follows: inconsistent with usual interstitial pneumonia (UIP) in 63 patients (98.4%), which included nonspecific interstitial pneumonia (NSIP) in 35 patients (55.6%), organizing pneumonia (OP) in 4 patients (6.3%), and OP with fibrosis in 22 patients (34.9%).ConclusionsThe characteristic CT findings of patients with anti-ARS-ILD were areas of ground-glass attenuation and reticulation, predominantly distributed as lower and peribronchovascular lesions, which is compatible with NSIP. One-third of patients showed OP with fibrosis

Effects of Aging and Display Contrast on the Legibility of Characters on Mobile Phone Screens

Nowadays, mobile phones are very popular in the world. The use of text email with short message service (SMS) is spreading. In this study, we evaluated the legibility of characters on the liquid crystal displays of mobile phones. When characters are small, younger people assure readability by shortening the viewing distance. However, elderly people find it far more difficult to see small characters. Moreover, legibility deteriorates as the contrast of display becomes lower

Micro gas turbine with ceramic nozzle and rotor part 2”,

ABSTRACT In order to develop a micro gas turbine with high turbine inlet temperature and thermal efficiency, a series of running tests has been carried out. J-850 jet engine (Sophia Precision Co., Ltd.) was chosen as a baseline machine. The turbine nozzle and the rotor are replaced by type SN-01 (Otsuka Ceramics Co., Ltd.) and type SN-235 (Kyocera Corporation) ceramic elements, respectively. By using type 3a engine, we succeeded one-hour running test of the engine without cooling and severe damages. The turbine inlet temperature was higher than 1000 o C. The rotating speed was about 120,000 rpm. Performances of the type 3a engine (with ceramic nozzle and rotor) and the type 1 (with Inconel alloy nozzle and ceramic rotor) were compared as follows: At the same rotation speed, turbine inlet temperature of the type 3a became higher than that of the type 1. Simultaneously, fuel consumption of type 3a was larger than that of the type 1. Thrust of the type 3a was slightly larger than that of the type 1. Those results imply that the thermal efficiency of type 3a is slightly, 2%, lower than that of the type 1. The present sealing configurations between ceramic nozzle-vanes and their holder plate and ceramic rotor-housing and metal combustion chamber were found to work well