10 research outputs found
Factors Regulating Preparations for Pets in the Event of a Disaster: An Examination of Psychological Relationships Between Pets and Owners
The Great East Japan Earthquake occurred in 2011, and the Kumamoto Earthquake occurred in 2016. These disasters affected not only humans but also many animals. The Ministry of the Environment formulated the “Disaster Preparedness Guideline for Humans and Pets” in 2018. The guidelines state that the self-help of pet owners is fundamental in dealing with disasters. With the aim of furthering preparations for pets in the event of a disaster, we conducted an exploratory investigation of the factors that facilitate or inhibit disaster preparation for pets and examined how the psychological relationships between pets and owners affects the degree of execution for “preparedness in everyday life” and “preparing for disasters.” We conducted an Internet-based survey of pet owners (N = 260). We then conducted ordinal logistic regression analyses with “preparedness in everyday life” and “preparing for disasters” as objective variables. We found that the “number of pet friendships” (friends made through interactions because of one’s pet) facilitated “preparedness in everyday life” and “preparing for disasters.” Moreover, the “degree of animal welfare practice” facilitated “preparedness in everyday life”, and the degree of “difficulty being separated from pets” facilitated “preparing for disasters.” We discussed the contributions and limitations of this study.本研究は,文部科学省プログラム広島大学「放射線災害復興を推進するフェニックスリーダー育成プログラム」による補助を受けた
Synthesis of Arecatannin A1 from Dimeric Epicatechin Electrophile
Synthesis of arrecatarmin A1 (1) was accomplished from dimeric epicatechin electrophile, which was prepared by Zn(OTf)(2) mediated self-condensation, and monomeric catechin nucleophile. The condensation was successfully worked using Yb(OTf)(3) as a Lewis acid in good yield.ArticleNATURAL PRODUCT COMMUNICATIONS. 10(6):959-962 (2015)journal articl
Syntheses of prodelphinidin B1, B2, and B4 and their antitumor activities against human PC-3 prostate cancer cell lines
Total synthesis of prodelphinidin B1, B2, and B4 has been accomplished. The key step is Lewis acid-mediated equimolar condensations between an epigallocatechin and/or a gallocatechin nucleophile and an epigallocatechin and/or a gallocatechin electrophile. The antitumor effects of synthetic prodelphinidin B1-B4 against human PC-3 prostate cancer cell lines have been investigated. These compounds showed significant antitumor effects. Their activity seemed to be little bit stronger than EGCG and prodelphinidin B3, known antitumor agent.ArticleTETRAHEDRON LETTERS. 54(52):7188-7192 (2013)journal articl
Syntheses of procyanidin B2 and B3 gallate derivatives using equimolar condensation mediated by Yb(OTf)(3) and their antitumor activities
Synthesis of procyanidin B2 and B3 gallate derivatives, 3-O-gallate, 3 ''-O-gallate, and 3,3 ''-di-O-gallate, were synthesized using equimolar condensation mediated by Yb(OTf)(3). Synthesized compounds showed significant antitumor effects against human prostate PC-3 cell lines. Their activities were weaker than well-known EGCG and prodelphinidin B3.ArticleBIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 23(17):4935-4939 (2013)journal articl
Syntheses of prodelphinidin B1, B2, and B4 and their antitumor activities against human PC-3 prostate cancer cell lines
Total synthesis of prodelphinidin B1, B2, and B4 has been accomplished. The key step is Lewis acid-mediated equimolar condensations between an epigallocatechin and/or a gallocatechin nucleophile and an epigallocatechin and/or a gallocatechin electrophile. The antitumor effects of synthetic prodelphinidin B1-B4 against human PC-3 prostate cancer cell lines have been investigated. These compounds showed significant antitumor effects. Their activity seemed to be little bit stronger than EGCG and prodelphinidin B3, known antitumor agent.ArticleTETRAHEDRON LETTERS. 54(52):7188-7192 (2013)journal articl