Ценник как жанр естественной письменной речи

Статья, посвященная исследованию ценника как речевого жанра естественной письменной русской речи, предполагает постановку и решение круга проблем, связанных со спецификой данной письменной формы общения и ее вариантов, с членением данного жанра разговорной письменной речи, с местом последней в различных сферах жизни и социальных взаимодействий людей

Proteoglycan neofunctions: regulation of inflammation and autophagy in cancer biology.

Inflammation and autophagy have emerged as prominent issues in the context of proteoglycan signaling. In particular, two small, leucine-rich proteoglycans, biglycan and decorin, play pivotal roles in the regulation of these vital cellular pathways and, as such, are intrinsically involved in cancer initiation and progression. In this minireview, we will address novel functions of biglycan and decorin in inflammation and autophagy, and analyze new emerging signaling events triggered by these proteoglycans, which directly or indirectly modulate these processes. We will critically discuss the dual role of proteoglycan-driven inflammation and autophagy in tumor biology, and delineate the potential mechanisms through which soluble extracellular matrix constituents affect the microenvironment associated with inflammatory and neoplastic diseases

Evaluation of a Generic Approach for Designing Domain Ontologies Based on XML Schemas

The process designing domain ontologies from scratch is very time-consuming and is associated with a lot of effort. In the most cases, domain experts have defined XML Schemas, describing domain data models, before ontologies have been created. Our idea is to generate ontologies out of XML Schemas automatically using XSLT transformations in a first step, and to derive domain ontologies semi-automatically using SWRL rules in a second step. We apply our approach in order to reuse the information located in the XML Schemas for the design of domain ontologies. In this paper, we aim to verify the hypothesis, that the effort and the time delivering high quality domain ontologies using the developed semi-automatic approach is much less than creating domain ontologies in a completely manual way. We have applied the individual stages of the suggested approach to multiple different data models in the academic and the industry domain. In addition to that, we show one complete use case for which the traditional approach designing domain ontologies manually and the proposed approach have been applied – the DDI-RDF Discovery Vocabulary, which is an ontology of the social science metadata standard Data Documentation Initiative

Reward system and temporal pole contributions to affective evaluation during a first person shooter video game

<p>Abstract</p> <p>Background</p> <p>Violent content in video games evokes many concerns but there is little research concerning its rewarding aspects. It was demonstrated that playing a video game leads to striatal dopamine release. It is unclear, however, which aspects of the game cause this reward system activation and if violent content contributes to it. We combined functional Magnetic Resonance Imaging (fMRI) with individual affect measures to address the neuronal correlates of violence in a video game.</p> <p>Results</p> <p>Thirteen male German volunteers played a first-person shooter game (<it>Tactical Ops: Assault on Terror</it>) during fMRI measurement. We defined success as eliminating opponents, and failure as being eliminated themselves. Affect was measured directly before and after game play using the Positive and Negative Affect Schedule (PANAS). Failure and success events evoked increased activity in visual cortex but only failure decreased activity in orbitofrontal cortex and caudate nucleus. A negative correlation between negative affect and responses to failure was evident in the right temporal pole (rTP).</p> <p>Conclusions</p> <p>The deactivation of the caudate nucleus during failure is in accordance with its role in reward-prediction error: it occurred whenever subject missed an expected reward (being eliminated rather than eliminating the opponent). We found no indication that violence events were directly rewarding for the players. We addressed subjective evaluations of affect change due to gameplay to study the reward system. Subjects reporting greater negative affect after playing the game had less rTP activity associated with failure. The rTP may therefore be involved in evaluating the failure events in a social context, to regulate the players' mood.</p