16 research outputs found
Generation of Oxidoreductases with Dual Alcohol Dehydrogenase and Amine Dehydrogenase Activity
Get PDFKinetic Resolution of Racemic Primary Amines Using <i>Geobacillus stearothermophilus</i> Amine Dehydrogenase Variant
Get PDFGeneration of Oxidoreductases with Dual Alcohol Dehydrogenase and Amine Dehydrogenase Activity
Get PDFKinetic Resolution of Racemic Primary Amines Using <i>Geobacillus stearothermophilus</i> Amine Dehydrogenase Variant
Get PDFA NADH‐dependent engineered amine dehydrogenase from Geobacillus stearothermophilus (LE‐AmDH‐v1) was applied together with a NADH‐oxidase from Streptococcus mutans (NOx) for the kinetic resolution of pharmaceutically relevant racemic α‐chiral primary amines. The reaction conditions (e. g., pH, temperature, type of buffer) were optimised to yield S‐configured amines with up to >99 % ee
Mechanistic Insight into the Catalytic Promiscuity of Amine Dehydrogenases:Asymmetric Synthesis of Secondary and Primary Amines
Get PDF
Mechanistic Insight into the Catalytic Promiscuity of Amine Dehydrogenases: Asymmetric Synthesis of Secondary and Primary Amines
No full text
Hydrogen-borrowing conversion of alcohols into optically active primary amines by combination of alcohol dehydrogenases and amine dehydrogenases
No full text
