1 research outputs found
Therapeutic hypothermia for neonatal hypoxic ischaemic encephalopathy should not be discontinued in low- and middle-income countries
Perinatal asphyxia is a major cause of death and disability in
children. Therapeutic hypothermia (TH) has become a standard
of care for newborn infants who have sustained hypoxic ischaemic
encephalopathy (HIE) due to perinatal asphyxia. There is compelling
evidence to support this approach. A Cochrane systematic review of
11 prospective randomised controlled trials including 1 505 newborns
showed that TH started within 6 hours of birth in infants with HIE
significantly decreased mortality and neurodevelopmental disability
in survivors.http://www.samj.org.zadm2022ImmunologyPaediatrics and Child Healt