Stability in controlled L-theory

We prove a squeezing/stability theorem for delta-epsilon controlled L-groups when the control map is a fibration on a finite polyhedron. A relation with boundedly-controlled L-groups is also discussed.Comment: This is the version published by Geometry & Topology Monographs on 22 April 200

4-Nitro-6-[(8-quinolyl­amino)­methyl­idene]cyclo­hexa-2,4-dien-1-one

The mol­ecule of the title compound, C16H11N3O3, exists in the keto form and the C=O and N—H bonds are mutually cis in the crystal structure. There are two crystallographically independent mol­ecules per asymmetric unit with broadly similar structural data. The only noticeable difference between the two is the dihedral angles between the benzene and the quinoline rings: 1.04 (4) and 3.07 (4)°. In the structure, intra­molecular N—H⋯O(carbon­yl) and N—H⋯N(pyridine) hydrogen bonds exist but there is no evidence of formal inter­molecular hydrogen-bonding associations

Implementation of a new specific program for training curators at Hiroshima University

博物館法施行規則の改正に伴い，2012年4月から学芸員資格取得のために修得すべき科目が大幅に変更となった。学芸員資格取得の歴史においてはきわめて大きな変更である。本学では，これに対応するため，各学部の学芸員資格取得特定プログラムを統合し，全学の学生を対象とする新課程に移行した。本稿では，本学が新たに採用した4学期制（ターム制）を含め，今回の変更が受講や資格取得にどのような影響を及ぼしたのか，統計データの分析を通じて考察した。新課程移行の前後で，プログラム登録者数，資格取得者数は大幅に減少し，取得率も大きく低下した。こうした現象は特定の学部，分野の変化に基づくものではなく，旧課程においてプログラム登録の主体となってきた全ての学部に共通する。分析を通じて，大幅な必要単位数の増加，全学を対象としたプログラムへの変更，2学期制から4学期制（ターム制）への変更など，複数の要因が関連して，各学部における専門の修得と学芸員資格取得を両立させることが困難な状況が生じていることが推定された。As a result of the revision of Museum Law Enforcement Rules, the subjects that must be completed to acquire the curator qualification have changed significantly since April 2012, which constitutes a major change in the history of this qualification. To cope with this change, we integrated the curator qualification specific programs of each faculty into a new course for students of all universities. In this paper, through statistical data analysis, we examined the impact of this change on attendance trends, including the term system newly adopted by Hiroshima University. Before and after the transition to the new course, the number of program registrants and qualifications greatly decreased, and the acquisition rate has also declined significantly. These phenomena were not based on changes in specific faculties or fields, but are common to all faculties subject to program registration during the old course. Through this analysis, we presumed that several factors, such as the great increase in the required number of credits, the change to the program for the whole school, and the change from a two-semester system to the four-semester system, were all interrelated to each other, which make it difficult to achieve both specialized and curator qualifications.本稿は，2018年6月22日に香川大学で開催された第13回日本博物科学会で口頭発表した藤野次史・青木孝夫・清水則雄・菅村 亨・本多博之・山口富美夫・山崎博史・吉田将之「広島大学における新課程実施後の学芸員資格取得状況について」を元に，新たなデータを加えて考察したものである

Strict De Novo Methylation of the 35S Enhancer Sequence in Gentian

A novel transgene silencing phenomenon was found in the ornamental plant, gentian (Gentiana triflora × G. scabra), in which the introduced Cauliflower mosaic virus (CaMV) 35S promoter region was strictly methylated, irrespective of the transgene copy number and integrated loci. Transgenic tobacco having the same vector did not show the silencing behavior. Not only unmodified, but also modified 35S promoters containing a 35S enhancer sequence were found to be highly methylated in the single copy transgenic gentian lines. The 35S core promoter (−90)-introduced transgenic lines showed a small degree of methylation, implying that the 35S enhancer sequence was involved in the methylation machinery. The rigorous silencing phenomenon enabled us to analyze methylation in a number of the transgenic lines in parallel, which led to the discovery of a consensus target region for de novo methylation, which comprised an asymmetric cytosine (CpHpH; H is A, C or T) sequence. Consequently, distinct footprints of de novo methylation were detected in each (modified) 35S promoter sequence, and the enhancer region (−148 to −85) was identified as a crucial target for de novo methylation. Electrophoretic mobility shift assay (EMSA) showed that complexes formed in gentian nuclear extract with the −149 to −124 and −107 to −83 region probes were distinct from those of tobacco nuclear extracts, suggesting that the complexes might contribute to de novo methylation. Our results provide insights into the phenomenon of sequence- and species- specific gene silencing in higher plants