Magnetic Properties of Precession Modes Built on High-K Multi-quasiparticle States in ^{178}W

We present an example that shows that the random phase approximation performed on high-K multi-quasiparticle configurations leads to a rotor picture by calculating excitation energies and magnetic properties of ^{178}W. Then we deduce the effective g_R of the high-K rotors and compare it with that of the low-K one.Comment: 6 pages, 3 figures, Prog. Theor. Phys., accepte

Large-Scale Structure of Short-Lived Lyman\alpha Emitters

Recently discovered large-scale structure of Ly\alpha Emitters (LAEs) raises a novel challenge to the cold dark matter (CDM) cosmology. The structure is extended over more than 50 Mpc at redshift z=3.1, and exhibits a considerably weak angular correlation. Such properties of LAE distributions appear to be incompatible with the standard biased galaxy formation scenario in the CDM cosmology. In this paper, by considering the possibility that LAEs are short-lived events, we attempt to build up the picture of LAEs concordant with the CDM cosmology. We find that if the lifetime of LAEs is as short as (6.7 \pm 0.6) \times 10^7 yr, the distributions of simulated galaxies successfully match the extension and morphology of large-scale structure of LAEs at z=3.1, and also the weak angular correlation function. This result implies that LAEs at z=3.1 do not necessarily reside in high density peaks, but tends to be located in less dense regions, in a different way from the expectation by the standard biased galaxy formation scenario. In addition, we make a prediction for the angular correlation function of LAEs at redshifts higher than 3. It is found that the prediction deviates from that by the standard biased galaxy formation scenario even at redshifts 4 < z < 6.Comment: 5 pages, 4 figures, accepted for publication in MNRA

Wobbling motion in triaxial superdeformed nuclei

We discuss some characteristic features of the wobbling motion excited on the triaxial superdeformed Lu nucleus. We show how these features are connected to the moments of inertia microscopically calculated by means of the quasiparticle RPA in the rotating frame.Comment: 6 pages, 7 figures, Proc. 6th China-Japan Joint Nuclear Physics Symposium, Shanghai, China, 2006, Ed. Y.-G. Ma and A.Ozaw

Leukemogenesis in Down syndrome

The incidence of leukemia is higher in Down syndrome children than that in the general population, while the risk of solid tumors is significantly reduced in Down syndrome. Recent studies utilizing mouse models have shown that distinct mechanisms caused by the elevated dosage of multiple genes is implicated in the protection from tumor progression depending on the type of solid neoplasm. In contrast, increased incidence of mutation in the several specific genes is reported as a cause of the onset of leukemias. Especially, acquired mutations in the GATA1 gene are associated with leukemogenesis of megakaryoblastic leukemia (AMKL) and transient myeloproliferative disorder (TMD) related to Down syndrome. The mutations are clustered in the region corresponding to the N-terminal domain of GATA1 and result in the production of the short form of GATA1 (GATA1-S), which utilizes Met84 as an alternative translation initiation codon. Efforts producing mouse models of Down TMD and AMKL have been undertaken, as these models seem to provide important insights into the pathogenesis of multistep leukemogenesis. Concomitantly, the function of GATA1 has been examined extensively, and the analyses present a prototype for the study of lineage-restricted transcription factors that play an essential role for the differentiation, proliferation, and apoptosis of erythroid cells, megakaryocytes, mast cells, and eosinophils. In this chapter, we will summarize recent progress in the studies of leukemias that occur in Down syndrome, especially in relation to GATA1 mutations