前期白亜紀の東・東南アジアのイグアノドン類：新しい系統と古生物地理

要約のみTohoku University西弘嗣論

Successful Vancomycin Dose Adjustment in a Sepsis patient with Bacterial Meningitis Using Cystatin C

Cystatin C-guided vancomycin (VCM) dosing is useful in critically ill patients. Its usefulness in septic patients with bacterial meningitis remains unknown, as there are no published reports. In this study, we sought to clarify its benefit. Cystatin C was used to guide VCM dosing in a septic bacterial meningitis patient with normal kidney function, according to therapeutic drug monitoring (TDM). Using cystatin C, the Bayesian method-based TDM made optimal VCM dosing possible, and decreased the predicted error (4.85 mg/L) compared to serum creatinine (16.83 mg/L). We concluded TDM of VCM using cystatin C can be considered in sepsis patients with bacterial meningitis with normal kidney function

New mammalian specimens from the Lower Cretaceous Kitadani Formation, Tetori Group, Fukui, Japan

<div><p>New specimens of two non-therian (non-tribosphenidan) mammals are described from the Lower Cretaceous Kitadani Formation in the upper part of the Tetori Group, Katsuyama, Fukui Prefecture, Japan. Despite their poor preservation, these specimens represent undescribed species from Japan, suggesting additional mammalian diversity in the Tetori Group. Previously, four mammal taxa had been formally described from this rock unit: a spalacotheriid ‘symmetrodont’, two eobaatarid multituberculates and a eutriconodont mammal. One of the new specimens is a damaged left p4 of a ‘plagiaulacidan’ grade multituberculate assignable to the family Eobaataridae. The Kitadani eobaatarid is a large species distinguished from the two previously described eobaatarids, <i>Tedoribaatar</i> and <i>Hakusanobaatar</i>, which are known from the stratigraphically lower Kuwajima Formation of the Tetori Group, Hakusan, Ishikawa Prefecture, Japan. It also differs from <i>Sinobaatar</i>, <i>Heishanobaatar</i> and <i>Liaobaatar</i> described from the Early Cretaceous of China. Another specimen, a partial right dentary with a faint Meckelian groove, is assigned to a eutriconodontan that is larger than and morphologically distinguishable from the eutriconodont <i>Hakusanodon</i> from the Kuwajima Formation. The Kitadani eutriconodontan is potentially related to the family Triconodontidae. The additional specimens from the Kitadani Formation shed new light on Early Cretaceous mammalian faunal change and dispersal in East Asia.</p></div

Empirical Evaluation of Cost Overrun Prediction with Imbalance Data

2011 10th IEEE/ACIS International Conference on Computer and Information Science, 16-18 May 2011, Sanya, ChinaTo prevent cost overrun of software projects, it is necessary for project managers to identify projects which have high risk of cost overrun in the early phase. So far, discriminant methods such as linear discriminant analysis and logistic regression have been used to predict cost overrun projects. However, accuracy of discriminant methods often becomes low when a dataset used for predict is imbalanced, i.e. there exists a large difference between the number of cost overrun projects and non cost overrun projects. In this paper, we compared accuracy of linear discriminant analysis, logistic regression, classification tree, Mahalanobis-Taguchi method, and collaborative filtering, by changing the percentage of cost overrun projects in the dataset. The result showed that collaborative filtering was highest accuracy among five methods. When the number of cost overrun projects and non cost overrun was balanced in the dataset, linear discriminant analysis was second highest accuracy, and when it was not balanced, Mahalanobis-Taguchi method was second highest among five methods