緩衝装置を用いたポケット式落石防護網の防護性能に関する研究

13301甲第4423号博士(工学)金沢大学博士論文要旨Abstrac

緩衝装置を用いたポケット式落石防護網の防護性能に関する研究

13301甲第4423号博士(工学)金沢大学博士論文本文Ful

Experiments on pocket-type rockfall protective nets at a real slope

Although pocket-type rockfall protective nets are more economical and easier to install, the amount of rockfall energy they can absorb and the locations where they can be used are limited. Because of this, in recent years, a new rockfall protective net, which has built-in shock absorbers to prevent anchor rods from breaking and to absorb considerable rockfall energy due to their function, has been designed. This study was conducted to determine the effective range of implementation for a new pocket-type rockfall protective net, and to confirm the net\u27s reaction and energy absorption capacity upon the introduction of rotational energy approximating the actual behavior of a rockfall

Experiments on pocket-type rockfall protective nets at a real slope

Although pocket-type rockfall protective nets are more economical and easier to install, the amount of rockfall energy they can absorb and the locations where they can be used are limited. Because of this, in recent years, a new rockfall protective net, which has built-in shock absorbers to prevent anchor rods from breaking and to absorb considerable rockfall energy due to their function, has been designed. This study was conducted to determine the effective range of implementation for a new pocket-type rockfall protective net, and to confirm the net\u27s reaction and energy absorption capacity upon the introduction of rotational energy approximating the actual behavior of a rockfall

Methanol stimulates the colony-formation rate in a human hepatoma cell line (HLE).

&#60;P&#62;Effects of methanol on colony-formation of human hepatoma cells were investigated. Among five human hepatoma cell lines (Hep G2, HLE, HuH-6, HuH-7, and PLC/PRF/5), only HLE cells showed enhanced colony formation due to methanol. The effective concentrations of methanol were around 1%. The enhancement occurred in a greater degree when the cells were seeded in the culture medium containing methanol than when methanol was added 24h after the cells were seeded. Methanol itself, however, did not enhance the cell proliferation.</p

Development of an X-ray HARP–FEA detector system for high-throughput protein crystallography

A new detector system for protein crystallography based on an X-ray HARP–FEA is presented

Prenatal diagnosis of severe mitochondrial diseases caused by nuclear gene defects: a study in Japan

Prenatal diagnoses of mitochondrial diseases caused by defects in nuclear DNA (nDNA) or mitochondrial DNA have been reported in several countries except for Japan. The present study aimed to clarify the status of prenatal genetic diagnosis of mitochondrial diseases caused by nDNA defects in Japan. A comprehensive genomic analysis was performed to diagnose more than 400 patients, of which, 13 families (16 cases) had requested prenatal diagnoses. Eight cases diagnosed with wild type homozygous or heterozygous variants same as either of the heterozygous parents continued the pregnancy and delivered healthy babies. Another eight cases were diagnosed with homozygous, compound heterozygous, or hemizygous variants same as the proband. Of these, seven families chose to terminate the pregnancy, while one decided to continue the pregnancy. Neonatal- or infantile-onset mitochondrial diseases show severe phenotypes and lead to lethality. Therefore, such diseases could be candidates for prenatal diagnosis with careful genetic counseling, and prenatal testing could be a viable option for families