Multi-quark baryons and color screening at finite temperature

We study baryons in SU(N) gauge theories at finite temperature according to the gauge/string correspondence based on IIB string theory. The baryon is constructed out of D5 brane and $N$ fundamental strings to form a color singlet $N$-quark bound state. At finite temperature and in the deconfining phase, we could find $k(<N)$-quark ``baryons''. Thermal properties of such $k$-quark baryons and also of the $N$-quark baryon are examined. We study the temperature dependence of color screening distance and Debye length of the baryon of $k$-quark and $N$-quark. We also estimate the melting temperature, where the baryons decay into quarks and gluons completely.Comment: 16 pages, 12 figure

D3/D7 holographic Gauge theory and Chemical potential

N=2 supersymmetric Yang-Mills theory with flavor hypermultiplets at finite temperature and in the dS${}_4$ are studied for finite quark number density ($n_b$) by a dual supergravity background with non-trivial dilaton and axion. The quarks and its number density $n_b$ are introduced by embedding a probe D7 brane. We find a critical value of the chemical potential at the limit of $n_b=0$, and it coincides with the effective quark mass given in each theory for $n_b=0$. At this point, a transition of the D7 embedding configurations occurs between their two typical ones. The phase diagrams of this transition are shown in the plane of chemical potential versus temperature and cosmological constant for YM theory at finite temperature and in dS${}_4$ respectively. In this phase transition, the order parameter is considered as $n_b$. % and the critical value of the chemical potential This result seems to be reasonable since both theories are in the quark deconfinement phase.Comment: 17 pages, 8 figure

Critical role for the EB1 and APC interaction in the regulation of microtubule polymerization

AbstractHuman EB1 was originally cloned as a protein that interacts with the COOH terminus of adenomatous polyposis coli (APC) [1]. Interestingly, this interaction is often disrupted in colon cancer, due to mutations in APC. EB1 also interacts with the plus-ends of microtubules and targets APC to microtubule tips [2–6]. Since APC is detected on the kinetochores of chromosomes, it has been hypothesized that the EB1-APC interaction connects microtubule spindles to the kinetochores and regulates microtubule stability [7–9]. In yeast, EB1 regulates microtubule dynamics [6, 10, 11], and its binding domain in APC may be conserved in Kar9, an EB1 binding protein involved in the microtubule-capturing mechanism [12–14]. These results suggest that the interaction of EB1 and APC is important and may be conserved. However, it is largely unknown whether the EB1-APC interaction affects microtubule dynamics. Here, we show that EB1 potently promotes microtubule polymerization in vitro and in permeabilized cells, but, surprisingly, only in the presence of the COOH-terminal EB1 binding domain of APC (C-APC). Significantly, this C-APC activity is abolished by phosphorylation, which also disrupts its ability to bind to EB1. Furthermore, yeast EB1 protein effectively substitutes for the human protein but also requires C-APC in promoting microtubule polymerization. Finally, C-APC is able to promote microtubule polymerization when stably expressed in APC mutant cells, demonstrating the ability of C-APC to promote microtubule assembly in vivo. Thus, the interaction between EB1 and APC plays an essential role in the regulation of microtubule polymerization, and a similar mechanism may be conserved in yeast

Spectral-Function Sum Rules in Supersymmetry Breaking Models

The technique of Weinberg's spectral-function sum rule is a powerful tool for a study of models in which global symmetry is dynamically broken. It enables us to convert information on the short-distance behavior of a theory to relations among physical quantities which appear in the low-energy picture of the theory. We apply such technique to general supersymmetry breaking models to derive new sum rules.Comment: 18 pages, 1 figur

Flavor quarks in AdS4 and gauge/gravity correspondence

The non-perturbative properties of the gauge theories in the AdS${}_4$ are studied in the dual supergravity by including light flavor quarks, which are introduced by a D7 brane embedding. Contrary to the cases of Minkowski and dS${}_4$, the dilaton does not play any important dynamical role in the AdS${}_4$ case, and the characteristic properties like the quark confinement and the chiral symmetry breaking are realized mainly due to the geometry AdS${}_4$. The possible hadron spectra %in the AdS${}_4$ are also examined, and we find that the meson spectra are well described by the formula given by the field theory in AdS${}_4$, but the characteristic mass scale is modified by the gauge interactions for exited states.Comment: 18 pages, 8 figure

Mesoscopic Multimodal Imaging Provides New Insight to Tumor Tissue Evaluation : An Example of Macrophage Imaging of Hepatic Tumor using Organosilica Nanoparticles

Multimodal imaging using novel multifunctional nanoparticles provides new approach to biomedical field. Thiol-organosilica nanoparticles containing iron oxide magnetic nanoparticles (MNPs) and rhodamine B (thiol OS-MNP/Rho) were applied to multimodal imaging of hepatic tumor of Long−Evans Cinnamon (LEC) rat. The magnetic resonance imaging (MRI) of LEC rats revealed tumors in the liver clearly and semi-quantitatively due to a labeling of macrophages in liver. The fluorescent imaging (FI) showed abnormal fluorescent patterns of the liver at the mesoscopic level that was between macroscopic and microscopic level. We performed correlation analysis between optical imaging including FI and MRI. We found that the labeled macrophages located specific area in the tumor tissue and influenced the tumor size on MRI. In addition histological observation showed the labeled macrophages related specific tissue in the pathological region. We demonstrated a new approach to evaluate tumor tissue at the macroscopic and microscopic level as well as mesoscopic level using multimodal imaging