Enjoyment (M±SE) of the three exercise trials.

<p>Enjoyment (M±SE) of the three exercise trials.</p

Rating of perceived exertion (M±SE) during the three exercise trials.

<p>Rating of perceived exertion (M±SE) during the three exercise trials.</p

Demographic characteristics of participants (n = 44).

<p><i>p-value reflects differences in men and women based on independent samples t-tests.</i></p><p>* <i>denotes significant differences between men and women</i></p><p>Demographic characteristics of participants (n = 44).</p

Feeling Scale responses (M±SE) during the three exercise trials.

<p>Feeling Scale responses (M±SE) during the three exercise trials.</p

Improvements in VO₂peak and exercise performance are greater following HI than LO.

<p>The mean VO₂peak (A) and time to 500 kcal (B) for the LO and HI groups are shown. The individual change in VO₂peak for all participants are also shown (C). *Significant (p<0.05) difference from Pre. † Significant (p<0.05) effect of training. ‡ Significant (p<0.05) interaction. ††Non-significant (p = 0.07) interaction.</p

Effects of HI and LO on PGC-1α, AMPK, and SIRT1 protein content.

<p>Changes in the protein content of PGC-1α, AMPK and SIRT1 (A). Representative western blots, including loading controls, are also shown (B). * Significant (p<0.05) effect of training. † Significant (p<0.05) interaction.</p

Effect of HI and LO on markers of skeletal muscle oxidative capacity.

<p>Changes in protein content of COX I and COX IV (A) and the maximal enzyme activities of citrate synthase (CS) and β-hydroxyacyl-CoA dehydrogenase (βHAD) (C). Representative western blots, including loading controls, are also shown (B). † Significant (p<0.05) effect of training. ‡ Non-significant (p = 0.07) effect of training.</p

Participant Characteristics.

<p>Values are mean ± SD. yrs, years; cm, centimetres; kg, kilograms; BMI, body mass index; m, metres; mmol/L, millimoles per litre; µIU, micro international units; HOMA-IR, homeostatic model assessment of insulin resistance; W, watts; s, seconds; HRpeak, maximal heart rate from VO₂peak test; bpm, beats per minute; Training HR, average heart rate from first training session. Interval WR, average power produced during intervals from first training session.</p>†<p>Significant (p<0.05) effect of training.</p>‡<p>Significantly different (p<0.05) from LO.</p>§<p>Significant (p<0.05) interaction between groups.</p

Peak O₂ pulse increases to a greater extent following HI than LO.

<p>*Significant (p<0.05) difference from Pre. † Significant (p<0.05) effect of training. ‡ Significant (p<0.05) interaction.</p