Profile of gross congenital malformations among live newborns and its associated risk factors from a tertiary care rural teaching institute

Background: Congenital malformations are defects in morphogenesis during early fetal life. The objective was to study the profile of gross congenital malformations among live newborns and its associated risk factors from a tertiary care rural teaching hospital of north India.Methods: It is a cross- sectional, descriptive. All the babies born in the hospital (live births) during January 2014 to December 2014 formed the baseline population and those with gross congenital malformations were included in the study. Antenatal records were assessed and mothers were interviewed for socio-demographic variables.Results: There were 6143 live births out of which 109 had gross congenital malformations giving an incidence of 1.7%. Central nervous system was most commonly affected (48%) followed by musculoskeletal (28%) and gastrointestinal system (13%). Incidence of congenital malformations was more among multi-parous females, preterm and low birth weight babies.Conclusions: A relative increase in the incidence of congenital malformations once again implies the importance of public health education and regular antenatal screening. We also, strongly recommend mandatory screening of all newborns by pediatrician after birth for timely detection and best possible treatment of these congenital malformations

Neonatal necrotizing fasciitis

Necrotizing fasciitis (NF) is an uncommon rapidly spreading infection of skin and subcutaneous tissue with systemic toxicity and fulminant course. The disease though relatively uncommon in pediatric and neonatal age group carries a high mortality unless diagnosed early and treated aggressively. Mono-microbial pseudomonas infection causing neonatal NF is a rarity and we, therefore, present one such neonate with fatal NF due to pseudomonas sepsis

Congenital constriction band syndrome: a case report

Congenital constriction bands are anomalous bands formed during antenatal period that encircle a digit or an extremity in a fetus leading to a wide spectrum of manifestations, ranging from shallow grooves to acrosyndactyly and amputations. It is also associated with skeletal and other birth defects like craniofacial abnormalities, spinal dysraphism, porencephaly, hydrancephaly and visceral body wall malformations. We hereby present one such case which presented to us with below knee amputation of the lower limb and syndactyly

Profile of neonatal dermatoses in a tertiary care teaching hospital of Haryana

Background: To assess the incidence and profile of neonatal dermatoses in a tertiary care hospital of Haryana and study its association with various perinatal risk factors.Methods: All inborn neonates (2.5kg while 859 (31.1%) had birth weight ≤2.5kg. 1223 (44.3%) were born to primipara while 1537 (55.6%) were born to multipara mothers. Mothers of 54 (1.9%) neonates were 30 years. 1806 (65.4%) neonates were born by normal vaginal delivery and 954 (34.6%) neonates were born by cesarean section. In 13 (0.5%) neonates, history of consanguinity was present while it was absent in 2747 (99.5%) neonates. Most common skin lesions observed were transient skin lesions among which Mongolian spots (62.9%), epstein pearls (48.8%), erythema toxicum (41.8%), milia (40.6%) and miniature puberty (35.9%) were the most common.Conclusions: Incidence of neonatal dermatoses was found to be higher (54.6%) among males as compared to females (45.4%); among term babies; those with birth weight >2.5kg; those born to multipara mothers; those born via normal vaginal delivery and those with maternal age 25-30 years

Profile of gross congenital malformations among live newborns and its associated risk factors from a tertiary care rural teaching institute

Background: Congenital malformations are defects in morphogenesis during early fetal life. The objective was to study the profile of gross congenital malformations among live newborns and its associated risk factors from a tertiary care rural teaching hospital of north India.Methods: It is a cross- sectional, descriptive. All the babies born in the hospital (live births) during January 2014 to December 2014 formed the baseline population and those with gross congenital malformations were included in the study. Antenatal records were assessed and mothers were interviewed for socio-demographic variables.Results: There were 6143 live births out of which 109 had gross congenital malformations giving an incidence of 1.7%. Central nervous system was most commonly affected (48%) followed by musculoskeletal (28%) and gastrointestinal system (13%). Incidence of congenital malformations was more among multi-parous females, preterm and low birth weight babies.Conclusions: A relative increase in the incidence of congenital malformations once again implies the importance of public health education and regular antenatal screening. We also, strongly recommend mandatory screening of all newborns by pediatrician after birth for timely detection and best possible treatment of these congenital malformations

Profile of neonatal dermatoses in a tertiary care teaching hospital of Haryana

Background: To assess the incidence and profile of neonatal dermatoses in a tertiary care hospital of Haryana and study its association with various perinatal risk factors.Methods: All inborn neonates (<28 days of life) including those seen in the outpatient department on follow up between November 2016 to April 2017 formed the baseline population and babies with skin lesions were included in the study. A detailed perinatal history and newborn examination of the baby was done by a pediatrician and all relevant details were recorded. Data was analyzed, and inferences were drawn using tables.Results: In our study, a total of 2760 newborn (1506 (54.6%) males and 1254 (45.4%) females) were studied. The incidence of neonatal dermatoses was found to be 94.1%. There were 1849 (66.9%) term, 853 (30.9%) preterm, and 58 (2.1%) post term neonates. 1901 (68.8%) had birth weight >2.5kg while 859 (31.1%) had birth weight ≤2.5kg. 1223 (44.3%) were born to primipara while 1537 (55.6%) were born to multipara mothers. Mothers of 54 (1.9%) neonates were < 20 years of age; 1157 (41.9%) in the age group of 20-25 years; 1324 (47.9%) in the age group of 25-30 years and 225 (8.1%) in the age group >30 years. 1806 (65.4%) neonates were born by normal vaginal delivery and 954 (34.6%) neonates were born by cesarean section. In 13 (0.5%) neonates, history of consanguinity was present while it was absent in 2747 (99.5%) neonates. Most common skin lesions observed were transient skin lesions among which Mongolian spots (62.9%), epstein pearls (48.8%), erythema toxicum (41.8%), milia (40.6%) and miniature puberty (35.9%) were the most common.Conclusions: Incidence of neonatal dermatoses was found to be higher (54.6%) among males as compared to females (45.4%); among term babies; those with birth weight >2.5kg; those born to multipara mothers; those born via normal vaginal delivery and those with maternal age 25-30 years