5 research outputs found
Effects of water deficit and rehydration on the polar lipid and membranes resistance leaves of Phaseolus vulgaris L. cv. Pérola
Bean leaves (Phaseolus vulgaris L.) cv. Pérola were used to evaluate the water deficit effects in polar lipids composition and in the electric conductivity. The results showed that the water deficiency a effected in the electrolytes loss which increased gradually in response to water deficit. This suggested a compartimentalization loss, due to the structural cellular membranes elements degradation. Total lipids contents decreased by reason of the water stress action. The polyunsaturated fatty acid contents (linoleic and linolenic acids) suffered a decrease while saturated fatty acid (palmitic and stearic acids) increased. The imbalance in the fatty saturated/unsaturated acid relation led to a reduction in the unsaturation index. The electrolytes loss increase related whith the to polyunsaturated fatty acid contents reduction suggested a larger dehydrated plants vulnerability, leading to a consequent loss in the productivity
The Receptor AT1 Appears to Be Important for the Maintenance of Bone Mass and AT2 Receptor Function in Periodontal Bone Loss Appears to Be Regulated by AT1 Receptor
A large number of experimental studies has demonstrated that angiotensin II (Ang II) is involved in key events of the inflammatory process. This study aimed to evaluate the role of Ang II type 1 (AT1) and Ang II type 2 (AT2) receptors on periodontitis. Methods: Experimental periodontitis was induced by placing a 5.0 nylon thread ligature around the second upper left molar of AT1 mice, no-ligature or ligature (AT1-NL and AT1-L), AT2 (AT2-NL or AT2-L) and wild type (WT-NL or L). Alveolar bone loss was scanned using Micro-CT. Cytokines, peptides and enzymes were analyzed from gingival tissues by Elisa and RT-PCR. Results: The blockade of AT1 receptor resulted in bone loss, even in healthy animals. Ang II receptor blockades did not prevent linear bone loss. Ang II and Ang 1-7 levels were significantly increased in the AT2-L (p < 0.01) group compared to AT2-NL and AT1-L. The genic expression of the Mas receptor was significantly increased in WT-L and AT2-L compared to (WT-NL and AT2-NL, respectively) and in AT1-L. Conclusions: Our data suggest that the receptor AT1 appears to be important for the maintenance of bone mass. AT2 receptor molecular function in periodontitis appears to be regulated by AT1