<創刊特集>大学は地域の歴史文化にどうかかわるのか : 地域連携の成果と課題

<p>Relative changes in postprandial plasma/serum excursions of glucose, pancreatic and gut hormones on day 4 and 42 expressed as mean change in total area under curve (tAUC) with day 0 as reference (with 95% confidence intervals (CI) in brackets), e.g. tAUC_PYY increased 40% from day 0 to day 4.</p><p><b>†</b> denotes p<0.05. CCK, cholecystokinin, GIP, glucose-dependent insulinotropic polypeptide, GLP-1, glucagon-like peptide-1, PYY, peptide YY.</p><p>Effect of Antibiotics on Gut Microbiota, Gut Hormones and Glucose Metabolism - Table 2 </p

Mean (±standard error of the mean) postprandial excursions of plasma gastrin, cholecystokinin (CCK), glucose-dependent insulinotropic polypeptide (GIP), glucagon-like-peptide 1 (GLP-1) and peptide YY (PYY) on day 0, 4 and 42.

<p>An acute reversible increase in plasma PYY concentration was seen following the antibiotics course, whereas no significant changes were seen in the plasma concentrations of the other gut hormones.</p

Abundance of faecal bacteria expressed as means (±standard error of the mean) of log₁₀-transformed number of colony forming units (CFU) per gram of faeces upon cultivation.

<p>The dotted line shows the lower detection limit. Reductions were observed in the abundance of faecal anaerobes, coliform, enterococci and bifidobacteria from day 0 to day 4. At 180 days after the antibiotics course, both the total aerobic and total anaerobic bacterial counts as well as the 3 specific bacterial groups had returned to the same levels as prior to the antibiotics course.</p

Number of participants reporting loose stools and diarrhoea in the days before, during and immediately after the antibiotics course.

<p>Loose stools are defined as stool consistency on the Bristol Stool Scale chart of >4. Diarrhoea was defined as 3 or more loose stools per day. All participants had loose stools after having received the antibiotic course for 3 days.</p