Problem of study in secondary schools

Thesis (Ed.M.)--Boston Universit

Poly-substance use and sexual risk behaviours: a cross-sectional comparison of adolescents in mainstream and alternative education settings

Background: Surveys of young people under-represent those in alternative education settings (AES), potentially disguising health inequalities. We present the first quantitative UK evidence of health inequalities between AES and mainstream education school (MES) pupils, assessing whether observed inequalities are attributable to socioeconomic, familial, educational and peer factors. Methods: Cross-sectional, self-reported data on individual- and poly-substance use (PSU: combined tobacco, alcohol and cannabis use) and sexual risk-taking from 219 pupils in AES (mean age 15.9 years) were compared with data from 4024 pupils in MES (mean age 15.5 years). Data were collected from 2008 to 2009 as part of the quasi-experimental evaluation of Healthy Respect 2 (HR2). Results: AES pupils reported higher levels of substance use, including tobacco use, weekly drunkenness, using cannabis at least once a week and engaging in PSU at least once a week. AES pupils also reported higher levels of sexual health risk behaviours than their MES counterparts, including: earlier sexual activity; less protection against sexually transmitted infections (STIs); and having 3+ lifetime sexual partners. In multivariate analyses, inequalities in sexual risk-taking were fully explained after adjusting for higher deprivation, lower parental monitoring, lower parent-child connectedness, school disengagement and heightened intentions towards early parenthood among AES vs MES pupils. However, an increased risk (OR = 1.73, 95% CI 1.15, 2.60) of weekly PSU was found for AES vs MES pupils after adjusting for these factors and the influence of peer behaviours. Conclusion: AES pupils are more likely to engage in health risk behaviours, including PSU and sexual risk-taking, compared with MES pupils. AES pupils are a vulnerable group who may not be easily targeted by conventional population-level public health programmes. Health promotion interventions need to be tailored and contextualised for AES pupils, in particular for sexual health and PSU. These could be included within interventions designed to promote broader outcomes such as mental wellbeing, educational engagement, raise future aspirations and promote resilience

Computer and Internet Use by Great Plains Farmers

This study uses data from a 2001 survey of Great Plains farmers to explore the adoption, usage patterns, and perceived benefits of computers and the Internet. Adoption results suggest that exposure to the technology through college, outside employment, friends, and family is ultimately more influential than farmer age and farm size. Notably, about half of those who use the Internet for farm-related business report zero economic benefits from it. Whether a farmer perceives that the Internet generates economic benefits depends primarily on how long the farmer has used the Internet for farm business and for what purposes.agriculture, competitiveness, net benefits, technology adoption, Research and Development/Tech Change/Emerging Technologies,

Computer and Internet Use by Great Plains Farmers

We use data from a 2001 survey of Great Plains farmers to explore the adoption, usage patterns, and perceived benefits of computers and the Internet. Our adoption results suggest that exposure to the technology through college, outside employment, friends, and family is ultimately more influential than farmer age and farm size. Notably, about half of those who use the Internet for farm-related business report zero economic benefits from it. Whether a farmer perceives that the Internet generates economic benefits depends primarily on how long the farmer has used the Internet for farm business and for what purposes.Farm Management, Research and Development/Tech Change/Emerging Technologies,

Examining biofilm growth and metabolism of Escherichia coli at laboratory scale using geoelectrical methods

To link geophysical field data to specific biological phenomena, controlled laboratory experiments are needed for the understanding of the response of geophysical parameters to changes in biological conditions. In this study, suspensions of bacteria were mixed with sand to create a biofilm growing on a surface and these mixtures were monitored using the geoelectrical spectral induced polarization method (SIP). The beginning growth of the biofilm was confirmed by scanning electron microscopy and the amount of bacteria in liquid and sand estimated using culture and DNA based methods (i.e. qPCR, quantitative polymerase chain reaction). While changes in SIP signal could not be clearly related to microbial activity, fluctuations in the phase shift were concomitant with the detection of two unidentified metabolites in the liquid extracted from the sand. These metabolites were only detected when the biofilm was produced under oxygen limiting conditions. Even though the experimental design was not optimal for the SIP measurements, the results support the idea that these measurements are not measuring cell mass but are influenced by the presence of smaller charged molecules that may be produced as microbial metabolites. As microbial metabolites would change in the field during bioremediation, this method could be applied for this type of monitoring

A Sustained Dietary Change Increases Epigenetic Variation in Isogenic Mice

Epigenetic changes can be induced by adverse environmental exposures, such as nutritional imbalance, but little is known about the nature or extent of these changes. Here we have explored the epigenomic effects of a sustained nutritional change, excess dietary methyl donors, by assessing genomic CpG methylation patterns in isogenic mice exposed for one or six generations. We find stochastic variation in methylation levels at many loci; exposure to methyl donors increases the magnitude of this variation and the number of variable loci. Several gene ontology categories are significantly overrepresented in genes proximal to these methylation-variable loci, suggesting that certain pathways are susceptible to environmental influence on their epigenetic states. Long-term exposure to the diet (six generations) results in a larger number of loci exhibiting epigenetic variability, suggesting that some of the induced changes are heritable. This finding presents the possibility that epigenetic variation within populations can be induced by environmental change, providing a vehicle for disease predisposition and possibly a substrate for natural selection.This work was supported by the Australian Research Council (DP0771859) and the National Health and Medical Research Council (#459412, #635510)

Speed and Energy Performance of an Asynchronous MIPS R3000 Microprocessor

This paper presents the speed and energy figures for an asynchronous implementation of a MIPS R3000 microprocessor. The design is almost entirely QDI and introduces a new fine-grained pipeline. The performance figures show that this design is four times as efficient as equivalent clocked designs and that its cycle time in FO4 units compares to that of high-performance dynamic pipelines