2,918 research outputs found

    A simple method for designing or analyzing an optical communication link

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    A simple method is described for determining the performance of a free space optical communication link. The method can be used either in the system design (synthesis) mode or in the performance evaluation (analysis) mode. Although restricted to photo counting based detection of pulse position modulated signals, the method is still sufficiently general to accommodate space-based, as well as ground-based, reception

    Monolithic electro-optic modulator array

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    A PIN GaAlAs diode structure is provided with parameters for index guiding of light in a single mode. The index of refraction of the central layer I (which in practice may be lightly doped .pi. or .nu.) is greater than the p- and n-layers to create a slab waveguide in the transverse direction. Stripe contacts define separate waveguide channels that are separated electrically and optically by implanting protons or etching grooves between the stripe contacts in the upper layer. Separate reverse biasing voltages may be applied to the stripe contacts for modulation of the light in proportions to the voltage, either with absorption modulation, if the light wavelength is within about 500.ANG. of the bandgap of the .pi.-material, or phase-delay modulation, if the wavelength is separated from the bandgap of the .pi.-material by at least 900.ANG.

    Growth responses of Ailanthus altissima seedlings to SO2

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    Growth of Ailanthus altissima (Mill.) Swingle seedlings exposed to various levels of sulphur dioxide (SO2) was observed. Exposure for 1 or 2 weeks at 260 [mu]gm-3 (0[middle dot]1 ppm) or 520 [mu]g m-3 (0[middle dot]2 ppm) of SO2 significantly (p 2 concentration.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/24357/1/0000626.pd

    Speech and language therapy for aphasia following stroke

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    Background  Aphasia is an acquired language impairment following brain damage that affects some or all language modalities: expression and understanding of speech, reading, and writing. Approximately one third of people who have a stroke experience aphasia.  Objectives  To assess the effects of speech and language therapy (SLT) for aphasia following stroke.  Search methods  We searched the Cochrane Stroke Group Trials Register (last searched 9 September 2015), CENTRAL (2015, Issue 5) and other Cochrane Library Databases (CDSR, DARE, HTA, to 22 September 2015), MEDLINE (1946 to September 2015), EMBASE (1980 to September 2015), CINAHL (1982 to September 2015), AMED (1985 to September 2015), LLBA (1973 to September 2015), and SpeechBITE (2008 to September 2015). We also searched major trials registers for ongoing trials including ClinicalTrials.gov (to 21 September 2015), the Stroke Trials Registry (to 21 September 2015), Current Controlled Trials (to 22 September 2015), and WHO ICTRP (to 22 September 2015). In an effort to identify further published, unpublished, and ongoing trials we also handsearched theInternational Journal of Language and Communication Disorders(1969 to 2005) and reference lists of relevant articles, and we contacted academic institutions and other researchers. There were no language restrictions.  Selection criteria  Randomised controlled trials (RCTs) comparing SLT (a formal intervention that aims to improve language and communication abilities, activity and participation) versus no SLT; social support or stimulation (an intervention that provides social support and communication stimulation but does not include targeted therapeutic interventions); or another SLT intervention (differing in duration, intensity, frequency, intervention methodology or theoretical approach).  Data collection and analysis  We independently extracted the data and assessed the quality of included trials. We sought missing data from investigators.  Main results  We included 57 RCTs (74 randomised comparisons) involving 3002 participants in this review (some appearing in more than one comparison). Twenty-seven randomised comparisons (1620 participants) assessed SLT versus no SLT; SLT resulted in clinically and statistically significant benefits to patients' functional communication (standardised mean difference (SMD) 0.28, 95% confidence interval (CI) 0.06 to 0.49, P = 0.01), reading, writing, and expressive language, but (based on smaller numbers) benefits were not evident at follow-up. Nine randomised comparisons (447 participants) assessed SLT with social support and stimulation; meta-analyses found no evidence of a difference in functional communication, but more participants withdrew from social support interventions than SLT. Thirty-eight randomised comparisons (1242 participants) assessed two approaches to SLT. Functional communication was significantly better in people with aphasia that received therapy at a high intensity, high dose, or over a long duration compared to those that received therapy at a lower intensity, lower dose, or over a shorter period of time. The benefits of a high intensity or a high dose of SLT were confounded by a significantly higher dropout rate in these intervention groups. Generally, trials randomised small numbers of participants across a range of characteristics (age, time since stroke, and severity profiles), interventions, and outcomes.  Authors' conclusions  Our review provides evidence of the effectiveness of SLT for people with aphasia following stroke in terms of improved functional communication, reading, writing, and expressive language compared with no therapy. There is some indication that therapy at high intensity, high dose or over a longer period may be beneficial. HIgh-intensity and high dose interventions may not be acceptable to all

    Hidden clusters: the articulation of agglomeration in City Regions

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    For many years, local economic development has been driven by the desire to maintain, attract and nurture clusters of economic activity in targeted industrial sectors. However, where clusters are not conventionally sector-based, public policy needs to develop alternative approaches to leverage the economic benefits and realise competitive advantage. Drawing on a study of the Sheffield City Region (SCR), the paper explores the challenge of leveraging ‘hidden’ cross-sectoral clusters, which do not fit dominant discourses of agglomeration-led growth. We posit that it is the cross-sectoral connections and networks in the SCR which represent its key strength, yet these are only partially reflected by current place marketing and policy considerations, and, in many ways, are overlooked and thus remain ‘hidden’. The paper argues that the competitive advantage of the SCR is undermined when it characterises clusters in terms of industrial sectors, and instead needs to articulate its strengths as a strategically important industrial centre. The paper concludes by drawing out a number of implications for academic theory and policy development

    Presynaptic actions of 4-Aminopyridine and γ-aminobutyric acid on rat sympathetic ganglia in vitro

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    Responses to bath-applications of 4-aminopyridine (4-AP) and -aminobutyric acid (GABA) were recorded intracellularly from neurones in the rat isolated superior cervical ganglion. 4-aminopyridine (0.1–1.0 mmol/l) usually induced spontaneous action potentials and excitatory postsynaptic potentials (EPSPs), which were blocked by hexamethonium. Membrane potential was unchanged; spike duration was slightly increased. Vagus nerve B-and C-fibre potentials were prolonged. In 4-AP solution (0.1–0.3 mmol/l), GABA (0.1 mmol/l), 3-aminopropanesulphonic acid or muscimol evoked bursts of spikes and EPSPs in addition to a neuronal depolarization. These bursts, which were not elicited by glycine, glutamate, taurine or (±)-baclofen, were completely antagonised by hexamethonium, tetrodotoxin or bicuculline methochloride. It is concluded that: (a) 4-AP has a potent presynaptic action on sympathetic ganglia; (b) presynaptic actions of GABA can be recorded postsynaptically in the presence of 4-AP; and (c) the presynaptic GABA-receptors revealed in this condition are similar to those on the postsynaptic membrane

    Supernova Remnants and Star Formation in the Large Magellanic Cloud

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    It has often been suggested that supernova remnants (SNRs) can trigger star formation. To investigate the relationship between SNRs and star formation, we have examined the known sample of 45 SNRs in the Large Magellanic Cloud to search for associated young stellar objects (YSOs) and molecular clouds. We find seven SNRs associated with both YSOs and molecular clouds, three SNRs associated with YSOs but not molecular clouds, and eight SNRs near molecular clouds but not associated with YSOs. Among the 10 SNRs associated with YSOs, the association between the YSOs and SNRs can be either rejected or cannot be convincingly established for eight cases. Only two SNRs have YSOs closely aligned along their rims; however, the time elapsed since the SNR began to interact with the YSOs' natal clouds is much shorter than the contraction timescales of the YSOs, and thus we do not see any evidence of SNR-triggered star formation in the LMC. The 15 SNRs that are near molecular clouds may trigger star formation in the future when the SNR shocks have slowed down to <45 km/s. We discuss how SNRs can alter the physical properties and abundances of YSOs.Comment: 24 pages, 5 figures, 1 table, Accepted for publication in the August 2010 edition of the Astronomical Journa

    Preferências pelas decisões compartilhadas em pacientes com depressão

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    Neste estudo, analisaram-se os processos psicológicos associados com as preferências dos pacientes com depressão na tomada de decisão sobre seu tratamento psiquiátrico. Participaram 462 pacientes diagnosticados com um transtorno depressivo agudo ou recorrente. A maior parte preferiu assumir um papel colaborativo-passivo ou totalmente passivo. Os resultados não mostraram diferenças significativas entre pacientes em função de sua cronicidade na preferência por tomada de decisões, embora um maior tempo de tratamento tenha sido associado com um estilo mais passivo. O MANCOVA aplicado ao total de participantes, controlando a idade, o nível educativo e o tempo de tratamento, indicou que os pacientes colaborativos e passivos mostraram maior lócus de controle centralizado na confiança no psiquiatra do que os ativos. Constataram-se diferenças de gênero que mostraram nos homens maior lócus de controle interno e reatância psicológica, e, nas mulheres, maior lócus centralizado no aleatório, o lócus centralizado no psiquiatra e uma percepção de menor autoeficácia. Os achados indicam a necessidade de estudar, sob uma perspectiva diferencial, a participação dos pacientes na tomada de decisão de acordo com os processos psicológicos e a repercussão que esta tem na aderência ao tratamento médico.En el presente estudio se analizaron los procesos psicológicos asociados con las preferencias de los pacientes con depresión en la toma de decisión sobre su tratamiento psiquiátrico. Participaron 462 pacientes diagnosticados con un trastorno depresivo agudo o recurrente. La mayor parte prefirió asumir un rol colaborativo-pasivo o totalmente pasivo. Los resultados no mostraron diferencias significativas entre pacientes en función de su cronicidad en la preferencia por la toma de decisiones, aunque un mayor tiempo de tratamiento se asoció con un estilo más pasivo. El MANCOVA aplicado al total de participantes, controlando la edad, el nivel educativo y el tiempo de tratamiento, indicó que los pacientes colaborativos y pasivos mostraron mayor locus de control centrado en la confianza en el psiquiatra que los activos. Se encontraron diferencias de género mostrando en los hombres mayor locus de control interno y reactancia psicológica, y en las mujeres, mayor locus centrado en el azar. Los análisis de regresión indicaron que en el caso de los hombres, la preferencia pasiva por la toma de decisión es explicada por el locus centrado en el psiquiatra. Sin embargo, en las mujeres tuvo mayor peso la edad, seguida del locus centrado en el azar, el locus centrado en el psiquiatra y una percepción de menor autoeficacia. Los hallazgos señalan la necesidad de estudiar desde una perspectiva diferencial la participación de los pacientes en la toma de decisión de acuerdo con los procesos psicológicos, así como la repercusión que esta tiene en la adherencia al tratamiento médico.This study analyzed the role of psychological processes predicting depressed patients’ preferences in clinical decision-making about psychiatric treatment. 462 patients diagnosed with depressive disorders, acute or recurrent, participated in a crosssectional survey. Most participants preferred collaborative-passive or totally passive roles. Results showed no significant differences between acute and recurrent patients in their preference of participation in decision-making, but longer treatment duration was associated with a more passive style. MANCOVA, controlling age, educational level and treatment duration variables, showed that collaborative and passive patients had a greater locus of control focused on their psychiatrist than active patients. Gender differences were found. Men showed greater internal locus of control and psychological reactance, while women showed greater external locus of control focused on chance. Regression analysis indicated that, for men, passive preferred role was explained by external locus centered on their psychiatrist. However, age registered the highest weight for women’ passive decision-making, followed by the locus focused on chance, locus focused on the psychiatrist and lower self-efficacy. Our findings suggest the need to study shared decision-making from a differential perspective that involves psychological processes and the impact of these processes in adherence to medical treatments

    X-ray line formation in the spectrum of SS 433

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    The mechanisms for the formation of X-ray lines in the spectrum of SS 433 are investigated by taking into account the radiative transfer inside the jets. The results of Monte Carlo numerical simulations are presented. The effect of a decrease in line intensity due to scattering inside the jet turns out to be pronounced, but it does not exceed 60% in magnitude on the entire grid of parameters. The line broadening due to scattering, nutational motion, and the contribution of satellites can lead to overestimates of the jet opening angle Θ\Theta from the line widths in Chandra X-ray observations. The fine structure of the lines turns out to be very sensitive to the scattering effects. This makes its investigation by planned X-ray observatories equipped with high-resolution spectrometers (primarily Astro-H) a powerful tool for diagnosing the parameters of the jets in SS 433.Comment: 23 pages, 14 figures, to be published in Astronomy Letters, v. 38, n. 7, p. 443 (2012
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