Risk factors for Coronavirus disease 2019 (Covid-19) death in a population cohort study from the Western Cape province, South Africa

Risk factors for coronavirus disease 2019 (COVID-19) death in sub-Saharan Africa and the effects of human immunodeficiency virus (HIV) and tuberculosis on COVID-19 outcomes are unknown. We conducted a population cohort study using linked data from adults attending public-sector health facilities in the Western Cape, South Africa. We used Cox proportional hazards models, adjusted for age, sex, location, and comorbidities, to examine the associations between HIV, tuberculosis, and COVID-19 death from 1 March to 9 June 2020 among (1) public-sector “active patients” (≥1 visit in the 3 years before March 2020); (2) laboratory-diagnosed COVID-19 cases; and (3) hospitalized COVID-19 cases. We calculated the standardized mortality ratio (SMR) for COVID-19, comparing adults living with and without HIV using modeled population estimates.Among 3 460 932 patients (16% living with HIV), 22 308 were diagnosed with COVID-19, of whom 625 died. COVID19 death was associated with male sex, increasing age, diabetes, hypertension, and chronic kidney disease. HIV was associated with COVID-19 mortality (adjusted hazard ratio [aHR], 2.14; 95% confidence interval [CI], 1.70–2.70), with similar risks across strata of viral loads and immunosuppression. Current and previous diagnoses of tuberculosis were associated with COVID-19 death (aHR, 2.70 [95% CI, 1.81–4.04] and 1.51 [95% CI, 1.18–1.93], respectively). The SMR for COVID-19 death associated with HIV was 2.39 (95% CI, 1.96–2.86); population attributable fraction 8.5% (95% CI, 6.1–11.1)

E-MOTION, un dispositif pour connaître l’expérience émotionnelle des visiteurs dans un musée

International audienceE-Motion allows us to know the verbalised and quantified emotional states of visitors during their visit to a museum. We explain the method that led us to propose a mobile device to indicate visitor emotions and able to spatially locate them during their visit while remaining non-invasive (there were no installation in the museum nor sensors put on visitors). This device had been tested in an ecological situation at the Palais des Beaux-Arts of Lille. We analyse the results and discuss the perspectives and the new orientations that they suggest.E-Motion permet de connaître les états émotionnels qualifiés et quantifiés des visiteurs durant leur parcours de visite dans un musée. Nous explicitons la méthode qui nous conduits à proposer un dispositif mobile de déclaration des émotions, capable de localiser les visiteurs pendant leur parcours, tout en restant non-invasif (pas d’installation dans l’espace ou de capteurs sur les visiteurs). Ce dispositif permet de visualiser la dynamique des valences déclarées par les visiteurs. Il a été testé en situation écologique au Palais des Beaux-Arts de Lille. Nous exposons les résultats et discutons les limites, les perspectives et les nouvelles orientations qu’ils suscitent

在美术馆标识参观者的情, 《艺术博物馆》杂志，中国美术出版总社

International audienc

Pertussis Toxin Reduces the Number of Splenic Foxp3 + Regulatory T Cells

International audienc