Reduced dynamics and Lagrangian submanifolds of symplectic manifolds

In this paper, we will see that the symplectic creed by Weinstein "everything is a Lagrangian submanifold" also holds for Hamilton-Poincar\'e and Lagrange-Poincar\'e reduction. In fact, we show that solutions of the Hamilton-Poincar\'e equations and of the Lagrange-Poincar\'e equations are in one-to-one correspondence with distinguished curves in a Lagrangian submanifold of a symplectic manifold. For this purpose, we will combine the concept of a Tulczyjew triple with Marsden-Weinstein symplectic reduction.Comment: 26 page

Gaseous diffusion coefficients. A comprehensive critical evaluation of experimental studies and correlations of results

Diffusion coefficients of dilute binary gas mixture

J Regularization Improves Imbalanced Multiclass Segmentation

We propose a new loss formulation to further advance the multiclass segmentation of cluttered cells under weakly supervised conditions. When adding a Youden's J statistic regularization term to the cross entropy loss we improve the separation of touching and immediate cells, obtaining sharp segmentation boundaries with high adequacy. This regularization intrinsically supports class imbalance thus eliminating the necessity of explicitly using weights to balance training. Simulations demonstrate this capability and show how the regularization leads to correct results by helping advancing the optimization when cross entropy stagnates. We build upon our previous work on multiclass segmentation by adding yet another training class representing gaps between adjacent cells. This addition helps the classifier identify narrow gaps as background and no longer as touching regions. We present results of our methods for 2D and 3D images, from bright field images to confocal stacks containing different types of cells, and we show that they accurately segment individual cells after training with a limited number of images, some of which are poorly annotated

Autoregression as a means of assessing the strength of seasonality in a time series

BACKGROUND: The study of the seasonal variation of disease is receiving increasing attention from health researchers. Available statistical tests for seasonality typically indicate the presence or absence of statistically significant seasonality but do not provide a meaningful measure of its strength. METHODS: We propose the coefficient of determination of the autoregressive regression model fitted to the data ([Image: see text]) as a measure for quantifying the strength of the seasonality. The performance of the proposed statistic is assessed through a simulation study and using two data sets known to demonstrate statistically significant seasonality: atrial fibrillation and asthma hospitalizations in Ontario, Canada. RESULTS: The simulation results showed the power of the [Image: see text] in adequately quantifying the strength of the seasonality of the simulated observations for all models. In the atrial fibrillation and asthma datasets, while the statistical tests such as Bartlett's Kolmogorov-Smirnov (BKS) and Fisher's Kappa support statistical evidence of seasonality for both, the [Image: see text] quantifies the strength of that seasonality. Corroborating the visual evidence that asthma is more conspicuously seasonal than atrial fibrillation, the calculated [Image: see text] for atrial fibrillation indicates a weak to moderate seasonality ([Image: see text] = 0.44, 0.28 and 0.45 for both genders, males and females respectively), whereas for asthma, it indicates a strong seasonality ([Image: see text] = 0.82, 0.78 and 0.82 for both genders, male and female respectively). CONCLUSIONS: For the purposes of health services research, evidence of the statistical presence of seasonality is insufficient to determine the etiologic, clinical and policy relevance of findings. Measurement of the strength of the seasonal effect, as can be determined using the [Image: see text] technique, is also important in order to provide a robust sense of seasonality

Four Years of Airborne Measurements of Wildfire Emissions in California, with a Focus on the Evolution of Emissions During the Soberanes Megafire

Biomass burning is an important source of trace gases and particles which can influence air quality on local, regional, and global scales. With wildfire events increasing due to changes in land use, increasing population, and climate change, characterizing wildfire emissions and their evolution is vital. In this work we report in situ airborne measurements of carbon dioxide (CO2), methane (CH4), water vapor (H2O), ozone (O3), and formaldehyde (HCHO) from nine wildfire events in California between 2013 and 2016, which were sampled as part of the Alpha Jet Atmospheric eXperiment (AJAX) based at NASA Ames Research Center. One of those fires, the Soberanes Megafire, began on 22 July 2016 and burned for three months. During that time, five flights were executed to sample emissions near and downwind of the Soberanes wildfire. In situ data are used to determine enhancement ratios (ERs), or excess mixing ratio relative to CO2, as well as assess O3 production from the fire. Changes in the emissions as a function of fire evolution are explored. Air quality impacts downwind of the fire are addressed using ground-based monitoring site data, satellite smoke products, and the Community Multiscale Air Quality (CMAQ) photochemical grid model

A general framework for nonholonomic mechanics: Nonholonomic Systems on Lie affgebroids

This paper presents a geometric description of Lagrangian and Hamiltonian systems on Lie affgebroids subject to affine nonholonomic constraints. We define the notion of nonholonomically constrained system, and characterize regularity conditions that guarantee that the dynamics of the system can be obtained as a suitable projection of the unconstrained dynamics. It is shown that one can define an almost aff-Poisson bracket on the constraint AV-bundle, which plays a prominent role in the description of nonholonomic dynamics. Moreover, these developments give a general description of nonholonomic systems and the unified treatment permits to study nonholonomic systems after or before reduction in the same framework. Also, it is not necessary to distinguish between linear or affine constraints and the methods are valid for explicitly time-dependent systems.Comment: 50 page

Influence of inhomogeneity on mechanical properties of commercially pure titanium processed by HPT

Already for fifteen years many researchers have been trying to discover metallic materials with unusual combinations of strength and ductility: with high strength and enhanced ductility . This combination may be achieved through different ways: alloying, nanostructuring, etc. This report is an attempt to analyze the influence of inhomogeneity of different types (structural, phase and space) on mechanical properties of commercially pure ti tanium (bulk and powder) subjected to high- pressure torsion. Experimental results for HPT bulk and powder titanium have demonstrated that mechanical behavior of CP titanium strongly depends on phase inhomogeneity (alpha + omega phases), structural inhomoge neity (bimodal grain size distribution) and space inhomogeneity (retained porosity) in case of cold consolidated Ti powder. High strength in HPT bulk titanium due to the formation of hard omega phase during HPT processing at room temperature was detected. The strong omega phase transforms back to nanograined alpha phase domains during short annealing at elevated temperature. HPT consolidation of titanium powder leads to the formation of brittle specimens showing high strength but almost zero plasticityPeer ReviewedPostprint (author's final draft

Translating the Diabetes Prevention Program into the Community The DEPLOY Pilot Study

Background The Diabetes Prevention Program (DPP) found that an intensive lifestyle intervention can reduce the development of diabetes by more than half in adults with prediabetes, but there is little information about the feasibility of offering such an intervention in community settings. This study evaluated the delivery of a group-based DPP lifestyle intervention in partnership with the YMCA. Methods This pilot cluster-randomized trial was designed to compare group-based DPP lifestyle intervention delivery by the YMCA to brief counseling alone (control) in adults who attended a diabetes risk-screening event at one of two semi-urban YMCA facilities and who had a BMI ≥24 kg/m2, ≥2 diabetes risk factors, and a random capillary blood glucose of 110–199 mg/dL. Multivariate regression was used to compare between-group differences in changes in body weight, blood pressures, HbA1c, total cholesterol, and HDL-cholesterol after 6 and 12 months. Results Among 92 participants, controls were more often women (61% vs 50%) and of nonwhite race (29% vs 7%). After 6 months, body weight decreased by 6.0% (95% CI=4.7, 7.3) in intervention participants and 2.0% (95% CI=0.6, 3.3) in controls (p<0.001; difference between groups). Intervention participants also had greater changes in total cholesterol (–22 mg/dL vs +6 mg/dL controls; p<0.001). These differences were sustained after 12 months, and adjustment for differences in race and gender did not alter these findings. With only two matched YMCA sites, it was not possible to adjust for potential clustering by site. Conclusions The YMCA may be a promising channel for wide-scale dissemination of a low-cost approach to lifestyle diabetes prevention

Microstructure and mechanical properties of AA6082-T6 by ECAP under warm processing

An AA6082 alloy deformed by equal channel angular pressing (ECAP) was studied. The evolution of microstructure as a function of the strain imparted was evaluated by optical microscopy (OM), scanning electron microscopy (SEM) coupled with an electron backscattered diffraction (EBSD) detector, X-ray diffraction (XRD) and Differential Scanning Calorimetry (DSC). XRD showed that MgSi2 precipitates developed in the ECAPed specimens. Texture analysis showed the apparition of two types of textures, one associated with shearing deformation and the second due to the recrystallization phenomena. Mechanical strength properties measured by tensile tests increased in the first ECAP pass, and then progressively diminished. This phenomenon was associated to the activation of continuous softening phenomena. Calorimetric analysis indicated a slightly rise in the recrystallization temperature of the deformed specimens. Also, the stored energy increased with rising ECAP passes due to the production of new dislocations. The average geometrically necessary dislocation (GND) density, measured by EBSD, increased with increasing ECAP passes. However, the rate of increase slows down with the progress of ECAP passes.Peer ReviewedPostprint (author's final draft

Editorial: ultrasound surveillance of hepatocellular carcinoma in the 21st century – authors’ reply

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/136042/1/apt13910.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/136042/2/apt13910_am.pd