Community based trial of home blood pressure monitoring with nurse-led telephone support in patients with stroke or transient ischaemic attack recently discharged from hospital.

BACKGROUND: High blood pressure in patients with stroke increases the risk of recurrence but management in the community is often inadequate. Home blood pressure monitoring may increase patients' involvement in their care, increase compliance, and reduce the need for patients to attend their General Practitioner if blood pressure is adequately controlled. However the value of home monitoring to improve blood pressure control is unclear. In particular its use has not been evaluated in stroke patients in whom neurological and cognitive ability may present unique challenges. DESIGN: Community based randomised trial with follow up after 12 months. PARTICIPANTS: 360 patients admitted to three South London Stroke units with stroke or transient ischaemic attack within the past 9 months will be recruited from the wards or outpatients and randomly allocated into two groups. All patients will be visited by the specialist nurse at home at baseline when she will measure their blood pressure and administer a questionnaire. These procedures will be repeated at 12 months follow up by another researcher blind as to whether the patient is in intervention or control group. INTERVENTION: INTERVENTION patients will be given a validated home blood pressure monitor and support from the specialist nurse. Control patients will continue with usual care (blood pressure monitoring by their practice). Main outcome measures in both groups after 12 months: 1. Change in systolic blood pressure.2. Cost effectiveness: Incremental cost of the intervention to the National Health Service and incremental cost per quality adjusted life year gained

Searching for young Jupiter analogs around AP Col: L-band high-contrast imaging of the closest pre-main sequence star

The nearby M-dwarf AP Col was recently identified by Riedel et al. 2011 as a pre-main sequence star (age 12 - 50 Myr) situated only 8.4 pc from the Sun. The combination of its youth, distance, and intrinsically low luminosity make it an ideal target to search for extrasolar planets using direct imaging. We report deep adaptive optics observations of AP Col taken with VLT/NACO and Keck/NIRC2 in the L-band. Using aggressive speckle suppression and background subtraction techniques, we are able to rule out companions with mass m >= 0.5 - 1M_Jup for projected separations a>4.5 AU, and m >= 2 M_Jup for projected separations as small as 3 AU, assuming an age of 40 Myr using the COND theoretical evolutionary models. Using a different set of models the mass limits increase by a factor of ~2. The observations presented here are the deepest mass-sensitivity limits yet achieved within 20 AU on a star with direct imaging. While Doppler radial velocity surveys have shown that Jovian bodies with close-in orbits are rare around M-dwarfs, gravitational microlensing studies predict that ~17% of these stars host massive planets with orbital separations of 1-10 AU. Sensitive high-contrast imaging observations, like those presented here, will help to validate results from complementary detection techniques by determining the frequency of gas giant planets on wide orbits around M-dwarfs.Comment: Accepted for publication in ApJ, 6 pages text ApJ style (incl. references), 4 figures, 1 tabl

A new Method to Constrain the Iron Abundance from Cooling Delays in Coronal Loops

Recent observations with TRACE reveal that the time delay between the appearance of a cooling loop in different EUV temperature filters is proportional to the loop length, dt_12 ~ L. We model this cooling delay in terms of radiative loss and confirm this linear relationship theoretically. We derive an expression that can be used to constrain the coronal iron enhancement alpha_Fe=A_Fe^cor/A_Fe^Ph relative to the photospheric value as function of the cooling delay dt_12, flux F_2, loop width w, and filling factor q_w < 1. With this relation we find upper limits on the iron abundance enhancement of alpha_Fe < 4.8+/-1.7 for 10 small-scale nanoflare loops, and alpha_Fe < 1.4+/-0.4 for 5 large-scale loops, in the temperature range of T~1.0-1.4 MK. This result supports the previous finding that low-FIP elements, including Fe, are enhanced in the corona. The same relation constitutes also a lower limit for the filling factor, which is q_w > 0.2+/-0.1 and q_w > 0.8+/-0.2 for the two groups of coronal loops.Comment: 2 Figure

The Finite Size Error in Many-body Simulations with long-Ranged Interactions

We discuss the origin of the finite size error of the energy in many-body simulation of systems of charged particles and we propose a correction based on the random phase approximation at long wave lengths. The correction comes from contributions mainly determined by the organized collective oscillations of the interacting system. Finite size corrections, both on kinetic and potential energy, can be calculated within a single simulation. Results are presented for the electron gas and silicon.Comment: 4 pages, 4 figures, submitted to PRL; corrected typo

Color in context: psychological context moderates the influence of red on approach- and avoidance-motivated behavior.

A basic premise of the recently proffered color-in-context model is that the influence of color on psychological functioning varies as a function of the psychological context in which color is perceived. Some research has examined the appetitive and aversive implications of viewing the color red in romance- and achievement-relevant contexts, respectively, but in all existing empirical work approach and avoidance behavior has been studied in separate tasks and separate experiments. Research is needed to directly test whether red influences the same behavior differently depending entirely on psychological context. The present experiment was designed to put this premise to direct test in romance- and achievement-relevant contexts within the same experimental paradigm involving walking behavior. Our results revealed that exposure to red (but not blue) indeed has differential implications for walking behavior as a function of the context in which the color is perceived. Red increased the speed with which participants walked to an ostensible interview about dating (a romance-relevant context), but decreased the speed with which they walked to an ostensible interview about intelligence (an achievement-relevant context). These results are the first direct evidence that the influence of red on psychological functioning in humans varies by psychological context. Our findings contribute to both the literature on color psychology and the broader, emerging literature on the influence of context on basic psychological processes

Nonequilibrium steady states in fluids of platelike colloidal particles

Nonequilibrium steady states in an open system connecting two reservoirs of platelike colloidal particles are investigated by means of a recently proposed phenomenological dynamic density functional theory [M. Bier and R. van Roij, Phys. Rev. E 76, 021405 (2007)]. The platelike colloidal particles are approximated within the Zwanzig model of restricted orientations, which exhibits an isotropic-nematic bulk phase transition. Inhomogeneities of the local chemical potential generate a diffusion current which relaxes to a nonvanishing value if the two reservoirs coupled to the system sustain different chemical potentials. The relaxation process of initial states towards the steady state turns out to comprise two regimes: a smoothening of initial steplike structures followed by an ultimate relaxation of the slowest diffusive mode. The position of a nonequilibrium interface and the particle current of steady states depend nontrivially on the structure of the reservoirs due to the coupling between translational and orientational degrees of freedom of the fluid

Structural and optical investigation of non-polar (1-100) GaN grown by the ammonothermal method

This article may be downloaded for personal use only. Any other use requires prior permission of the author and AIP Publishing. This article appeared in Journal of Applied Physics 113, 203513 (2013) and may be found at https://doi.org/10.1063/1.4807581.We studied the structural and optical properties of state-of-the-art non-polar bulk GaN grown by the ammonothermal method. The investigated samples have an extremely low dislocation density (DD) of less than 5 × 104 cm−2, which results in very narrow high-resolution x-ray rocking curves. The a and c lattice parameters of these stress-free GaN samples were precisely determined by using an x-ray diffraction technique based on the modified Bond method. The obtained values are compared to the lattice parameters of free-standing GaN from different methods and sources. The observed differences are discussed in terms of free-electron concentrations, point defects, and DD. Micro Raman spectroscopy revealed a very narrow phonon linewidth and negligible built-in strain in accordance with the high-resolution x-ray diffraction data. The optical transitions were investigated by cathodoluminescence measurements. The analysis of the experimental data clearly demonstrates the excellent crystalline perfection of ammonothermal GaN material and its potential for fabrication of non-polar substrates for homoepitaxial growth of GaN based device structures

Modeling Socially Desirable Responding and Its Effects

The impact of socially desirable responding or faking on noncognitive assessments remains an issue of strong debate. One of the main reasons for the controversy is the lack of a statistical method to model such response sets. This article introduces a new way to model faking based on the assumption that faking occurs due to an interaction between person and situation. The technique combines a control group design with structural equation modeling and allows a separation of trait and faking variance. The model is introduced and tested in an example. The results confirm a causal nfluence of faking on means and covariance structure of a Big 5 questionnaire. Both effects can be reversed by the proposed model. Finally, a real-life criterion was implemented and predicted by both variance sources. In this example, it was the trait but not the faking variance that was predictive. Implications for research and practice are discussed

Spectroscopy of Globular Clusters in M81

We present moderate-resolution spectroscopy of globular clusters (GCs) around the Sa/Sb spiral galaxy M81 (NGC 3031). Sixteen candidate clusters were observed with the Low Resolution Imaging Spectrograph on the Keck I telescope. All are confirmed as bona fide GCs, although one of the clusters appears to have been undergoing a transient event during our observations. In general, the M81 globular cluster system (GCS) is found to be very similar to the Milky Way (MW) and M31 systems, both chemically and kinematically. A kinematic analysis of the velocities of 44 M81 GCS, (the 16 presented here and 28 from previous work) strongly suggests that the red, metal-rich clusters are rotating in the same sense as the gas in the disk of M81. The blue, metal-poor clusters have halo-like kinematics, showing no evidence for rotation. The kinematics of clusters whose projected galactocentric radii lie between 4 and 8 kpc suggest that they are rotating much more than those which lie outside these bounds. We suggest that these rotating, intermediate-distance clusters are analogous to the kinematic sub-population in the metal-rich, disk GCs observed in the MW and we present evidence for the existence of a similar sub-population in the metal-rich clusters of M31. With one exception, all of the M81 clusters in our sample have ages that are consistent with MW and M31 GCs. One cluster may be as young as a few Gyrs. The correlations between absorption-line indices established for MW and M31 GCs also hold in the M81 cluster system, at least at the upper end of the metallicity distribution (which our sample probes). On the whole, the mean metallicity of the M81 GCS is similar to the metallicity of the MW and M31 GCSs. The projected mass of M81 is similar to the masses of the MW and M31. Its mass profile indicates the presence of a dark matter halo.Comment: 35 pages, including 11 figures and 9 tables. Accepted for publication in the Astronomical Journa