Использование учебных видео-материалов в образовательном процессе высшего учебного заведения

This article is devoted to the creation and use of educational video clips in higher educational institutions. This article analyzes the results of studies on the impact of video content on listeners, which showed a large degree of positive impact, presents a theoretical analysis of the basics of developing video materials. The purpose of the article is to create a technology for developing instructional videos in a higher educational institution. The authors presented the experience of implementing video materials in the classroom on pedagogical disciplines. The stages of developing video materials were proposed, recommendations for creating video were highlighted, the conditions and tasks of using video materials in the educational process were substantiated. Experience allowed us to identify the possibilities of video materials in the modern learning process, which can significantly increase the effectiveness of the teaching activities of the teacher and increase the level of students' perception of the material.Este artículo está dedicado a la creación y uso de videoclips educativos en instituciones de educación superior. Este artículo analiza los resultados de estudios sobre el impacto del contenido de video en los oyentes, que mostraron un alto grado de impacto positivo, presenta un análisis teórico de los conceptos básicos del desarrollo de materiales de video. El propósito del artículo es crear una tecnología para desarrollar videos instructivos en una institución de educación superior. Los autores presentaron la experiencia de implementar materiales de video en el aula sobre disciplinas pedagógicas. Se propusieron las etapas de desarrollo de los materiales de video, se resaltaron las recomendaciones para la creación de video, se confirmaron las condiciones y las tareas de uso de materiales de video en el proceso educativo. La experiencia nos permitió identificar las posibilidades de los materiales de video en el proceso de aprendizaje moderno, lo que puede aumentar significativamente la efectividad de las actividades de enseñanza del maestro y aumentar el nivel de percepción del material por parte de los estudiantes.Данная статья посвящена вопросам создания и использования учебных видео-роликов в высших учебных заведениях. В данной статье проанализированы результаты исследований влияния видео-контента на слушателей, показавшие большую степень положительного воздействия, представлен теоретический анализ основ разработки видео-материалов. Цель статьи состоит в создании технологии разработки обучающего видео в условиях высшего образовательного учреждения. Авторами представлен опыт реализации видео-материалов на занятиях по педагогическим дисциплинам. Были предложены этапы разработки видео-материалов, выделены рекомендации к созданию видео, обоснованы условия и задачи использования видео-материалов в учебном процессе. Опыт позволил выявить возможности видео-материалов в современном процессе обучения, которые позволяют существенно повысить результативность обучающей деятельности преподавателя и увеличить уровень восприятия студентами материала

Lengths of quasi-commutative pairs of matrices

In this paper we discuss some partial solutions of the length conjecture which describes the length of a generating system for matrix algebras. We consider mainly the algebras generated by two matrices which are quasi-commuting. It is shown that in this case the length function is linearly bounded. We also analyze which particular natural numbers can be realized as the lengths of certain special generating sets and prove that for commuting or product-nilpotent pairs all possible numbers are realizable, however there are non-realizable values between lower and upper bounds for the other quasi-commuting pairs. In conclusion we also present several related open problems

Departamento de processo educacional em condições de implementação de treinamento interativo de engenheiros futuros

Because of the established new socio-economic situation in the country that led to changes in the sphere of education, there is a need for modernization of education based on information technologies. One of the most important in this situation is interactive training. The new model of the student "learner", in contrast to the "learner", requires searching for actual ways of managing the educational process. Both the teacher and the student in the modern educational process should be equal, however, the teacher is assigned a leading role and he must manage the learning process without going beyond the subjectsubject relationship. The purpose of the article is to consider practical experience of managing educational process in conditions of application of interactive technologies in the training of engineers. The article explores the interactive course, located on the electronic platform Moodle for a more complete study of the management of training of engineering students. The variant of application of interactive technologies in Nizhny Novgorod State Pedagogical University named after KozmaMinin is offered at an auditor and extracurricular independent studying by students of a theoretical material. The results of real pedagogical practice are presented. It is indicated that in the course of work methods such as problem lectures, problem seminars, group discussions on various topics, brainstorming, a round table, case-tasks, simulation exercises, trainings, business games are used. The article shows the real practice of using Moodle at the university. The tools are shown with the help of which the teacher can manage the activities of the student, adjust his training.Debido a la nueva situación socioeconómica establecida en el país que llevó a cambios en la esfera de la educación, existe una necesidad de modernización de la educación basada en las tecnologías de la información. Uno de los más importantes en esta situación es la formación interactiva. El nuevo modelo del estudiante "aprendiz", en contraste con el "aprendiz", requiere la búsqueda de formas reales de gestionar el proceso educativo. Tanto el docente como el alumno en el proceso educativo moderno deben ser iguales; sin embargo, se le asigna un papel de liderazgo y debe gestionar el proceso de aprendizaje sin ir más allá de la relación sujeto-sujeto. El propósito del artículo es considerar la experiencia práctica de administrar el proceso educativo en condiciones de aplicación de tecnologías interactivas en la capacitación de ingenieros. El artículo explora el curso interactivo, ubicado en la plataforma electrónica Moodle para un estudio más completo de la gestión de la formación de estudiantes de ingeniería. La variante de la aplicación de tecnologías interactivas en la Universidad Pedagógica Estatal de Nizhny Novgorod, llamada así por KozmaMinin, se ofrece a un auditor y un estudio extracurricular independiente realizado por estudiantes de un material teórico. Se presentan los resultados de la práctica pedagógica real. Se indica que en el curso de los métodos de trabajo tales como conferencias de problemas, seminarios de problemas, discusiones de grupo sobre diversos temas, lluvia de ideas, una mesa redonda, tareas de casos, ejercicios de simulación, entrenamientos, juegos de negocios se utilizan. El artículo muestra la práctica real de usar Moodle en la universidad. Las herramientas se muestran con la ayuda de la cual el profesor puede gestionar las actividades del alumno, ajustar su formación.Devido à nova situação socioeconômica estabelecida no país, que levou a mudanças na esfera da educação, há necessidade de modernização da educação baseada nas tecnologias da informação. Um dos mais importantes nessa situação é o treinamento interativo. O novo modelo de "aprendiz" estudantil, em contraste com o "aprendiz", requer a busca de formas reais de gerenciar o processo educacional. Tanto o professor quanto o aluno no processo educacional moderno devem ser iguais; no entanto, ele é atribuído a um papel de liderança e deve gerenciar o processo de aprendizagem sem ir além da relação sujeitosujeito. O objetivo do artigo é considerar a experiência prática de gerenciar o processo educacional em condições de aplicação de tecnologias interativas na formação de engenheiros. O artigo explora o curso interativo, localizado na plataforma eletrônica do Moodle, para um estudo mais completo do gerenciamento de treinamento de estudantes de engenharia. A variante da aplicação de tecnologias interativas na Universidade Pedagógica Estado de Nizhny Novgorod, nomeado para KozmaMinin, ofereceu um auditor e um estudo extracurricular independente por estudantes de material teórico. Os resultados da prática pedagógica real são apresentados. É indicado que, no decorrer de métodos de trabalho, tais como conferências de problemas, seminários de problemas, discussões em grupo sobre vários tópicos, brainstorming, uma mesa redonda, tarefas de casos, exercícios de simulação, treinamentos, jogos de negócios são usar. O artigo mostra a prática real de usar o Moodle na universidade. As ferramentas são mostradas com a ajuda de que o professor pode gerenciar as atividades do aluno, ajustar seu treinamento

Ambiente educacional como recurso de desenvolvimento para o processo de aprendizagem

Following overseas examples, educational institutions in Russia are trying to interact with other organizations implementing practical competence approach. The relevance of the topic lies in the fact that modern educational environment is constantly changing both due to the dynamics of everyday and professional conditions. Due to competence approach constant monitoring and new resources are required for the development of each subject in this educational environment. The goal of the work is to create means for open social and educational environment realization which allows achieving positive results for all participants in the project. In this article, the authors raise the issue of modern educational environment creation as a resource for each subject of the educational process development.The article attempts to improve students’, teachers’ and others participants’ interested in educational environment development interaction. We try to achieve a qualitatively new level of participants’ skills and competencies development in this process. For this, analysis of the essence and structure of educational process in a higher educational institution was carried out. After that, the authors propose, within the framework of a project implemented by Nizhny Novgorod State Pedagogical University on the organization and development of the social and educational environment, to conduct special computer literacy courses for the elderly. The courses offered combine the activities of a large number of people who, working for a common result, achieve the development of individual qualities. The results obtained are the basis for further improvement of educational environment.Siguiendo ejemplos en el extranjero, las instituciones educativas en Rusia están tratando de interactuar con otras organizaciones implementando un enfoque de competencia práctica. La relevancia del tema radica en el hecho de que el entorno educativo moderno está cambiando constantemente debido a la dinámica de las condiciones cotidianas y profesionales. Debido al enfoque de competencia, el monitoreo constante y nuevos recursos son necesarios para el desarrollo de cada asignatura en este entorno educativo. El objetivo del trabajo es crear medios para la realización de un entorno social y educativo abierto que permita lograr resultados positivos para todos los participantes en el proyecto. En este artículo, los autores plantean el tema de la creación de un entorno educativo moderno como un recurso para cada tema del desarrollo del proceso educativo.El artículo intenta mejorar la interacción entre los estudiantes, los maestros y otros participantes interesados en el desarrollo del entorno educativo. Intentamos alcanzar un nivel cualitativamente nuevo de desarrollo de habilidades y competencias de los participantes en este proceso. Para ello, se realizó un análisis de la esencia y estructura del proceso educativo en una institución de educación superior. Posteriormente, los autores proponen, en el marco de un proyecto implementado por la Universidad Pedagógica Estatal Nizhny Novgorod sobre la organización y el desarrollo del entorno social y educativo, realizar cursos especiales de alfabetización informática para personas mayores. Los cursos ofrecidos combinan las actividades de un gran número de personas que, trabajando por un resultado común, logran el desarrollo de cualidades individuales.Na sequência de exemplos no exterior, instituições educacionais na Rússia estão tentando interagir com outras organizações implementando uma abordagem de competência prática. A relevância do tema reside no fato de que o ambiente educacional moderno está em constante mudança, tanto devido à dinâmica das condições cotidianas e profissionais. Devido à abordagem de competência, monitoramento constante e novos recursos são necessários para o desenvolvimento de cada disciplina nesse ambiente educacional. O objetivo do trabalho é criar meios para a realização de um ambiente social e educacional aberto que permita alcançar resultados positivos para todos os participantes do projeto. Neste artigo, os autores levantam a questão da criação de ambientes educacionais modernos como recurso para cada sujeito do processo de desenvolvimento educacional.O artigo tenta melhorar a interação dos alunos, professores e outros participantes interessados na interação do desenvolvimento do ambiente educacional. Tentamos alcançar um nível qualitativamente novo de desenvolvimento de habilidades e competências dos participantes neste processo. Para isso, foi realizada a análise da essência e estrutura do processo educacional em uma instituição de ensino superior. Em seguida, os autores propõem, no âmbito de um projeto implementado pela Universidade Pedagógica Estadual Nizhny Novgorod, a organização e desenvolvimento do ambiente socioeducacional, para a realização de cursos especiais de alfabetização em informática para idosos. Os cursos oferecidos combinam as atividades de um grande número de pessoas que, trabalhando por um resultado comum, alcançam o desenvolvimento de qualidades individuai

Role of mitochondria in the pheromone- and amiodarone-induced programmed death of yeast

Although programmed cell death (PCD) is extensively studied in multicellular organisms, in recent years it has been shown that a unicellular organism, yeast Saccharomyces cerevisiae, also possesses death program(s). In particular, we have found that a high doses of yeast pheromone is a natural stimulus inducing PCD. Here, we show that the death cascades triggered by pheromone and by a drug amiodarone are very similar. We focused on the role of mitochondria during the pheromone/amiodarone-induced PCD. For the first time, a functional chain of the mitochondria-related events required for a particular case of yeast PCD has been revealed: an enhancement of mitochondrial respiration and of its energy coupling, a strong increase of mitochondrial membrane potential, both events triggered by the rise of cytoplasmic [Ca2+], a burst in generation of reactive oxygen species in center o of the respiratory chain complex III, mitochondrial thread-grain transition, and cytochrome c release from mitochondria. A novel mitochondrial protein required for thread-grain transition is identified

Tyrosol induces multiple drug resistance in yeast Saccharomyces cerevisiae

In yeast, multiple (pleiotropic) drug resistance (MDR) transporters efflux xenobiotics from the cytoplasm to the environment. Additionally, upon the accumulation of xenobiotics in the cells, MDR genes are induced. At the same time, fungal cells can produce secondary metabolites with physico-chemical properties similar to MDR transporter substrates. Nitrogen limitation in yeast Saccharomyces cerevisiae leads to the accumulation of phenylethanol, tryptophol, and tyrosol, which are products of aromatic amino acid catabolism. In this study, we investigated whether these compounds could induce or inhibit MDR in yeast. Double deletion of PDR1 and PDR3 genes, which are transcription factors that upregulate the expression of PDR genes, reduced yeast resistance to high concentrations of tyrosol (4–6 g/L) but not to the other two tested aromatic alcohols. PDR5 gene, but not other tested MDR transporter genes (SNQ2, YOR1, PDR10, PDR15) contributed to yeast resistance to tyrosol. Tyrosol inhibited the efflux of rhodamine 6G (R6G), a substrate for MDR transporters. However, preincubating yeast cells with tyrosol induced MDR, as evidenced by increased Pdr5-GFP levels and reduced yeast ability to accumulate Nile red, another fluorescent MDR-transporter substrate. Moreover, tyrosol inhibited the cytostatic effect of clotrimazole, the azole antifungal. Our results demonstrate that a natural secondary metabolite can modulate yeast MDR. We speculate that intermediates of aromatic amino acid metabolites coordinate cell metabolism and defense mechanisms against xenobiotics

Resolution on the results of the first working meeting of the scientific advisory board «Actual problems of glycemic variability as a new criterion of glycemic control and safety of diabetes therapy»

The Scientific Advisory Board, chaired by Professor G. R. Galstyan (cochair - A.V. Zilov), met in Moscow on 19 June 2018 to discuss the possibilities of improving the results of diabetes mellitus (DM) treatment by considering glycaemic variability (GV) as an additional criterion for effective glycaemic control (especially in patients receiving insulin therapy) and as one of the goals of treatment in patients with unstable glycaemia. The purpose of the working meeting was to develop a strategy for the introduction of GV as a predictor and as an additional criterion for assessing the effectiveness and safety of hypoglycaemic therapy to improve the pharmacotherapy of diabetes and reduce cardiovascular and total mortality. The aims of the working meeting were to conduct a comprehensive data analysis of the relationship between GV and hypoglycaemia; to gather and analyse published data and the experience of decrease in GV and improved outcomes of diabetes against the background of different types of insulin therapy; to compare existing methods of glycaemia monitoring and GV assessment and examine their validity and availability in real practice in the context of limited budget and to analyse the informativeness and clinical and prognostic significance of various parameters of GV assessment and to determine their reasonable ‘minimum’ for a comprehensive assessment of GV as a criterion for evaluating the effectiveness of DM treatment and the predictors of negative diabetes outcomes. The following reports were presented during the discussion: ‘Glycemic variability: clinical and prognostic value. Types of glycemic variability’ (Candidate of Medical Sciences, assistant Professor Zilov A.V.); ‘Methods of assessment of variability of glycemia in clinical trials and routine practice’ (PhD, Professor Markova T. N.); ‘Current international and national recommendations on glycemic monitoring’ (PhD, Professor Galstyan G. R.) and ‘Peculiarities of glycemic variability and its evaluation among children and adolescents’ (Candidate of Medical Sciences Vitebskaya A.V.)

Засоби розробки WebAR: огляд

Web augmented reality (WebAR) development tools aimed at improving the visual aspects of learning are far from being visual and available themselves. This causing problems of selecting and testing WebAR development tools for CS undergraduates mastering in web-design basics. The research is aimed at conducting comparative analysis of WebAR tools to select those appropriated for beginners.Інструменти розробки доповненої реальності в Інтернеті (WebAR), спрямовані на покращення візуальних аспектів навчання, далеко не візуальні та доступні самі по собі. Це викликає проблеми з вибором та тестуванням засобів розробки WebAR для CS-студентів, які опановують основи веб-дизайну. Дослідження спрямоване на проведення порівняльного аналізу інструментів WebAR для відбору інструментів, призначених для початківців