Topic Strategies and the Internal Structure of Nominal Arguments in Greek and Italian

In this article, we argue that a set of unexpected contrasts in the interpretation of clitic-left-dislocated indefinites in Greek and Italian derive from structural variation in the nominal syntax of the two languages. Greek resists nonreferential indefinites in clitic left-dislocation, resorting to the topicalization of an often bare noun for nonreferential topics. By contrast, clitic left-dislocation is employed in Italian for topics regardless of their definite/indefinite interpretation. We argue that this contrast is directly linked to the wide availability of bare nouns in Greek, which stems from a structural difference in the nominal syntax of the two languages. In particular, we hypothesize that Greek nominal arguments lack a D layer. Rather, they are Number Phrases. We situate this analysis in the context of Chierchia’s (1998) typology of nominals. We argue that, on a par with Italian nouns, Greek nouns are [−arg, +pred]. However, they do not employ a syntactic head (D) for type-shifting to e . Rather, they resort to covert type-shifting, a hypothesis that is necessary to account for the distribution and interpretations of bare nouns in Greek, vis-à-vis other [−arg, +pred] languages like Italian and French. </jats:p

Defining the causes of sporadic Parkinson's disease in the global Parkinson's genetics program (GP2)

The Global Parkinson’s Genetics Program (GP2) will genotype over 150,000 participants from around the world, and integrate genetic and clinical data for use in large-scale analyses to dramatically expand our understanding of the genetic architecture of PD. This report details the workflow for cohort integration into the complex arm of GP2, and together with our outline of the monogenic hub in a companion paper, provides a generalizable blueprint for establishing large scale collaborative research consortia

Multi-ancestry genome-wide association meta-analysis of Parkinson?s disease

Although over 90 independent risk variants have been identified for Parkinson’s disease using genome-wide association studies, most studies have been performed in just one population at a time. Here we performed a large-scale multi-ancestry meta-analysis of Parkinson’s disease with 49,049 cases, 18,785 proxy cases and 2,458,063 controls including individuals of European, East Asian, Latin American and African ancestry. In a meta-analysis, we identified 78 independent genome-wide significant loci, including 12 potentially novel loci (MTF2, PIK3CA, ADD1, SYBU, IRS2, USP8, PIGL, FASN, MYLK2, USP25, EP300 and PPP6R2) and fine-mapped 6 putative causal variants at 6 known PD loci. By combining our results with publicly available eQTL data, we identified 25 putative risk genes in these novel loci whose expression is associated with PD risk. This work lays the groundwork for future efforts aimed at identifying PD loci in non-European populations

NoMoATS: Towards Automatic Detection of Mobile Tracking

Today’s mobile apps employ third-party advertising and tracking (A&T) libraries, which may pose a threat to privacy. State-of-the-art detects and blocks outgoing A&T HTTP/S requests by using manually curated filter lists (e.g. EasyList), and recently, using machine learning approaches. The major bottleneck of both filter lists and classifiers is that they rely on experts and the community to inspect traffic and manually create filter list rules that can then be used to block traffic or label ground truth datasets. We propose NoMoATS – a system that removes this bottleneck by reducing the daunting task of manually creating filter rules, to the much easier and scalable task of labeling A&T libraries. Our system leverages stack trace analysis to automatically label which network requests are generated by A&T libraries. Using NoMoATS, we collect and label a new mobile traffic dataset. We use this dataset to train decision tree classifiers, which can be applied in real-time on the mobile device and achieve an average F-score of 93%. We show that both our automatic labeling and our classifiers discover thousands of requests destined to hundreds of different hosts, previously undetected by popular filter lists. To the best of our knowledge, our system is the first to (1) automatically label which mobile network requests are engaged in A&T, while requiring to only manually label libraries to their purpose and (2) apply on-device machine learning classifiers that operate at the granularity of URLs, can inspect connections across all apps, and detect not only ads, but also tracking

NoMoAds: Effective and Efficient Cross-App Mobile Ad-Blocking

Abstract Although advertising is a popular strategy for mobile app monetization, it is often desirable to block ads in order to improve usability, performance, privacy, and security. In this paper, we propose NoMoAds to block ads served by any app on a mobile device. NoMoAds leverages the network interface as a universal vantage point: it can intercept, inspect, and block outgoing packets from all apps on a mobile device. NoMoAds extracts features from packet headers and/or payload to train machine learning classifiers for detecting ad requests. To evaluate NoMoAds, we collect and label a new dataset using both EasyList and manually created rules. We show that NoMoAds is effective: it achieves an F-score of up to 97.8% and performs well when deployed in the wild. Furthermore, NoMoAds is able to detect mobile ads that are missed by EasyList (more than one-third of ads in our dataset). We also show that NoMoAds is efficient: it performs ad classification on a per-packet basis in real-time. To the best of our knowledge, NoMoAds is the first mobile ad-blocker to effectively and efficiently block ads served across all apps using a machine learning approach

NoMoAds: Effective and Efficient Cross-App Mobile Ad-Blocking

Abstract Although advertising is a popular strategy for mobile app monetization, it is often desirable to block ads in order to improve usability, performance, privacy, and security. In this paper, we propose NoMoAds to block ads served by any app on a mobile device. NoMoAds leverages the network interface as a universal vantage point: it can intercept, inspect, and block outgoing packets from all apps on a mobile device. NoMoAds extracts features from packet headers and/or payload to train machine learning classifiers for detecting ad requests. To evaluate NoMoAds, we collect and label a new dataset using both EasyList and manually created rules. We show that NoMoAds is effective: it achieves an F-score of up to 97.8% and performs well when deployed in the wild. Furthermore, NoMoAds is able to detect mobile ads that are missed by EasyList (more than one-third of ads in our dataset). We also show that NoMoAds is efficient: it performs ad classification on a per-packet basis in real-time. To the best of our knowledge, NoMoAds is the first mobile ad-blocker to effectively and efficiently block ads served across all apps using a machine learning approach