Effect of batch initial velocity on the glass furnace efficiency

Glass manufacturing is a heat intensive process. There is a direct coloration between the batch distribution techniques and the furnace energy consumption, productivity, and quality of the glass manufactured. All four major segments (float, container, fibre, and specialty glasses) would benefit from using an optimised batch distribution technique where possible. Oscillating batch chargers (OBC) have been in use since the early 70s, despite their superior batch shape, coverage, and in turn positive effects on the energy consumption (Soleimanian, TMS 2013) and productivity of the furnace they are almost exclusively used in container glass manufacturing. The OBC’s main difference compared with other charging methods is its ability to directly influence the batch initial velocity. This paper reports on results achieved in two CFD models (in Flow 3D and GFM) used to study effect of the machine on the overall energy consumption in the doghouse and the melt space

Mothers’ and fathers’ perceptions of marital relationships and coparenting twins during school transition

Coparenting and the marital relationship are closely related yet distinct family subsystems hypothesized to influence one another. Little is known about these processes with consideration of more than one child in the family, which may have important implications. Here, we specifically focus on families with young twins, enabling us to account for sibling age-difference confounds, as well as due to the greater parenting demands and higher divorce rates in twin families. Using cross-lagged models for both mothers and fathers, we examined bidirectional associations between coparenting and the marital relationship during children’s transition to formal schooling. Parents of twins from 107 ‘intact’ families reported perceptions of coparenting and the marital relationship via telephone interview at Time 1 (Mchild age = 4years 8 months, SDchild age = 4.44 months) and questionnaire at Time 2 (Mchild age = 6 years, SDchild age = 6.12 months). Accounting for within-time associations and temporal stability for both mothers and fathers, coparenting was positively associated with subsequent reports of the marital relationship; there was no evidence of reciprocal associations between the marital relationship and subsequent coparenting. As children transition to primary school, the quality of coparenting may be a driver of the quality of the marital relationship for parents of twins. Those seeking to improve the marital relationship should pay due attention to perceptions of coparenting

A harsh parenting team? Maternal reports of coparenting and coercive parenting interact in association with children’s disruptive behaviour

Background: Parenting and coparenting are both important for children’s adjustment, but their interaction has been little explored. Using a longitudinal design and considering two children per family, we investigated mothers’ and fathers’ perceptions of coparenting as moderators of associations between their coercive parenting and children’s disruptive behaviour. Methods: Mothers and fathers from 106 ‘intact’ families were included from the Twins, Family and Behaviour study (TFaB). At Time 1 (Mchild age=3 years 11 months, SDchild age=4.44 months) parents reported on their coercive parenting and children’s disruptive behaviour via questionnaire; at Time 2 (Mchild age=4 years 8 months, SDchild age=4.44 months) perceptions of coparenting and the marital relationship were collected by telephone interview. Questionnaire-based reports of children’s disruptive behaviour were collected at follow-up (Mchild age=5 years 11 months, SDchild age=5.52 months). Multilevel modelling was used to examine child-specific and family-wide effects. Results: Conservative multilevel models including both maternal and paternal perceptions demonstrated that maternal perceptions of coparenting and overall coercive parenting interacted in their prediction of parent-reported child disruptive behaviour. Specifically, accounting for perceived marital quality, behavioural stability, and fathers’ perceptions, only in the context of perceived higher quality coparenting was there a positive association between mother-reported overall coercive parenting and children’s disruptive behaviour at follow-up. Conclusions: When combined with highly coercive parenting, maternal perceptions of high quality coparenting may be detrimental for children’s adjustment

Code Blue Emergencies: A Team Task Analysis and Educational Initiative

Introduction: The objective of this study was to identify factors that have a positive or negative influence on resuscitation team performance during emergencies in the operating room (OR) and post-operative recovery unit (PAR) at a major Canadian teaching hospital. This information was then used to implement a team training program for code blue emergencies. Methods: In 2009/10, all OR and PAR nurses and 19 anesthesiologists at Vancouver General Hospital (VGH) were invited to complete an anonymous, 10 minute written questionnaire regarding their code blue experience. Survey questions were devised by 10 recovery room and operation room nurses as well as 5 anesthesiologists representing 4 different hospitals in British Columbia. Three iterations of the survey were reviewed by a pilot group of nurses and anesthesiologists and their feedback was integrated into the final version of the survey. Results: Both nursing staff (n = 49) and anesthesiologists (n = 19) supported code blue training and believed that team training would improve patient outcome. Nurses noted that it was often difficult to identify the leader of the resuscitation team. Both nursing staff and anesthesiologists strongly agreed that too many people attending the code blue with no assigned role hindered team performance. Conclusion: Identifiable leadership and clear communication of roles were identified as keys to resuscitation team functioning. Decreasing the number of people attending code blue emergencies with no specific role, increased access to mock code blue training, and debriefing after crises were all identified as areas requiring improvement. Initial team training exercises have been well received by staff

Solving Einstein's Equations With Dual Coordinate Frames

A method is introduced for solving Einstein's equations using two distinct coordinate systems. The coordinate basis vectors associated with one system are used to project out components of the metric and other fields, in analogy with the way fields are projected onto an orthonormal tetrad basis. These field components are then determined as functions of a second independent coordinate system. The transformation to the second coordinate system can be thought of as a mapping from the original ``inertial'' coordinate system to the computational domain. This dual-coordinate method is used to perform stable numerical evolutions of a black-hole spacetime using the generalized harmonic form of Einstein's equations in coordinates that rotate with respect to the inertial frame at infinity; such evolutions are found to be generically unstable using a single rotating coordinate frame. The dual-coordinate method is also used here to evolve binary black-hole spacetimes for several orbits. The great flexibility of this method allows comoving coordinates to be adjusted with a feedback control system that keeps the excision boundaries of the holes within their respective apparent horizons.Comment: Updated to agree with published versio

Lattice dynamics and vibrational spectra of the orthorhombic, tetragonal and cubic phases of methylammonium lead iodide

The hybrid halide perovskite CH3NH3PbI3 exhibits a complex structural behaviour, with successive transitions between orthorhombic, tetragonal and cubic polymorphs at ca. 165 K and 327 K. Herein we report first-principles lattice dynamics (phonon spectrum) for each phase of CH3NH3PbI3. The equilibrium structures compare well to solutions of temperature-dependent powder neutron diffraction. By following the normal modes we calculate infrared and Raman intensities of the vibrations, and compare them to the measurement of a single crystal where the Raman laser is controlled to avoid degradation of the sample. Despite a clear separation in energy between low frequency modes associated with the inorganic PbI3 network and high-frequency modes of the organic CH3NH3+ cation, significant coupling between them is found, which emphasises the interplay between molecular orientation and the corner-sharing octahedral networks in the structural transformations. Soft modes are found at the boundary of the Brillouin zone of the cubic phase, consistent with displacive instabilities and anharmonicity involving tilting of the PbI6 octahedra around room temperature.Comment: 9 pages, 4 figure

The effects of anxiety and situation-specific context on perceptual–motor skill: a multi-level investigation

We examined the effects of anxiety and situation- specific contextual information on attentional, interpretational, and behavioural processes underpinning perceptual– motor performance as proposed by Nieuwenhuys and Oudejans (2012) using an in situ task. Twelve skilled cricket batsmen played against a skilled spin bowler under conditions manipulated to induce low and high levels of anxiety and the presence of low and high levels of situation-specific context. High anxiety decreased the number of good bat– ball contacts, while high levels of situation-specific context increased the number of times the ball was missed. When under high anxiety, participants employed significantly more fixations of shorter duration to more locations, but the effects of anxiety were restricted to the attentional level only. Situation-specific context affected performance and behavioural measures but not anxiety, cognitive load or perceptual–cognitive processes, suggesting that performance is influenced through different mechanisms from anxiety that are independent of working memory load

LIM kinase inhibitors disrupt mitotic microtubule organization and impair tumor cell proliferation

The actin and microtubule cytoskeletons are critically important for cancer cell proliferation, and drugs that target microtubules are widely-used cancer therapies. However, their utility is compromised by toxicities due to dose and exposure. To overcome these issues, we characterized how inhibition of the actin and microtubule cytoskeleton regulatory LIM kinases could be used in drug combinations to increase efficacy. A previously-described LIMK inhibitor (LIMKi) induced dose-dependent microtubule alterations that resulted in significant mitotic defects, and increased the cytotoxic potency of microtubule polymerization inhibitors. By combining LIMKi with 366 compounds from the GSK Published Kinase Inhibitor Set, effective combinations were identified with kinase inhibitors including EGFR, p38 and Raf. These findings encouraged a drug discovery effort that led to development of CRT0105446 and CRT0105950, which potently block LIMK1 and LIMK2 activity in vitro, and inhibit cofilin phosphorylation and increase αTubulin acetylation in cells. CRT0105446 and CRT0105950 were screened against 656 cancer cell lines, and rhabdomyosarcoma, neuroblastoma and kidney cancer cells were identified as significantly sensitive to both LIMK inhibitors. These large-scale screens have identified effective LIMK inhibitor drug combinations and sensitive cancer types. In addition, the LIMK inhibitory compounds CRT0105446 and CRT0105950 will enable further development of LIMK-targeted cancer therapy