Consumption, Happiness, and Climate Change

In this article, we explore the implications of this literature for understanding the relationship between climate change policies and consumption. We identify a number of ways in which accounting for the implications of the new happiness literature could lead to laws and policies that influence consumption in ways that increase the prospects for reducing greenhouse gas emissions in developed and developing countries. We do not examine every nuance of the growing happiness literature, but we provide a brief introduction and observations that we hope will stimulate further efforts by academicians and policymakers.happiness, life satisfaction, subjective well-being

Assessing Bias in Regression Estimates Using Monte Carlo Simulations: Examples in Criminal Justice Research

Can we trust published results? Problems with bias in reported results: “Do social scientists even know anything?” Failed replications (“repligate”). Inaccurate inferences about important relationships (Type I and Type II errors). Inaccurate power analyses for future studies. To avoid these problems, researchers need tools to rigorously evaluate statistical models. The Monte Carlo method is one tool that can be used to evaluate bias in model estimateshttps://digitalscholarship.unlv.edu/gcua_symposium/1008/thumbnail.jp

Holocene-Neogene volcanism in northeastern Australia: chronology and eruption history

Quaternary and late Neogene volcanism is widespread in northeastern Australia, producing at least 397 eruptions covering more than 20,000 km2, including at least 20 flows over 50 km long. Despite this abundance of young volcanism, before this study numerous eruptions had tentative ages or were undated, and the area requires a comprehensive evaluation of eruption patterns through time. To help address these issues we applied multi-collector ARGUS-V 40Ar/39Ar geochronology to determine the age of four of the younger extensive flows: Undara (160 km long, 189 ± 4/4 ka; 2σ, with full analytical/external uncertainties), Murronga (40 km long, 153 ± 5/5 ka), Toomba (120 km long, 21 ± 3/3 ka), and Kinrara (55 km long, 7 ± 2/2 ka). Verbal traditions of the Gugu Badhun Aboriginal people contain features that may potentially describe the eruption of Kinrara. If the traditions do record this eruption, they would have been passed down for 230 ± 70 generations – a period of time exceeding the earliest written historical records. To further examine north Queensland volcanism through time we compiled a database of 337 ages, including 179 previously unpublished K-Ar and radiocarbon results. The compiled ages demonstrate that volcanic activity has occurred without major time breaks since at least 9 Ma. The greatest frequency of eruptions occurred in the last 2 Ma, with an average recurrence interval of <10–22 ka between eruptions. Activity was at times likely more frequent than these calculations indicate, as the geochronologic dataset is incomplete, with undated eruptions, and intraplate volcanism is often episodic. The duration, frequency, and youthfulness of activity indicate that north Queensland volcanism should be considered as potentially still active, and there are now two confirmed areas of Holocene volcanism in eastern Australia – one at each end of the continent. More broadly, our data provides another example of 40Ar/39Ar geochronology applied to Holocene and latest Pleistocene mafic eruptions, further demonstrating that this method has the ability to examine eruptions and hazards at the youngest volcanoes on Earth

Large Magnetic Fields and Motions of OH Masers in W75 N

We report on a second epoch of VLBA observations of the 1665 and 1667 MHz OH masers in the massive star-forming region W75 N. We find evidence to confirm the existence of very strong (~40 mG) magnetic fields near source VLA 2. The masers near VLA 2 are dynamically distinct and include a very bright spot apparently moving at 50 km/s relative to those around VLA 1. This fast-moving spot may be an example of a rare class of OH masers seen in outflows in star-forming regions. Due to the variability of these masers and the rapidity of their motions, tracking these motions will require multiple observations over a significantly shorter time baseline than obtained here. Proper motions of the masers near VLA 1 are more suggestive of streaming along magnetized shocks rather than Keplerian rotation in a disk. The motions of the easternmost cluster of masers in W75 N (B) may be tracing slow expansion around an unseen exciting source.Comment: 7 pages including 4 figures (2 color) & 3 tables, to appear in Ap

Climate Change Governance: Boundaries and Leakage

This article provides a critical missing piece to the global climate change governance puzzle: how to create incentives for the major developing countries to reduce carbon emissions. The major developing countries are projected to account for 80% of the global emissions growth over the next several decades, and substantial reductions in the risk of catastrophic climate change will not be possible without a change in this emissions path. Yet the global climate governance measures proposed to date have not succeeded and may be locking in disincentives as carbon-intensive production shifts from developed to developing countries. A multi-pronged governance approach will be necessary. We identify a new strategy that will be an important component of any successful effort. Our strategy recognizes that in the context of climate change the simplified Coasian approach to pollution should be updated to include a more complete view of the options firms face in response to emissions reduction pressure and the sources of that pressure. We demonstrate how governments and non-governmental organizations can use expanded corporate carbon reporting boundaries and product carbon disclosure to harness social norms in developed countries. This informal social license pressure, in turn, will create incentives for firms to seek emissions reductions from their domestic and global supply chains. The private market pressure conveyed through supply chains will reduce leakage from developed countries, create new incentives for developing country firms and national governments, and play a surprisingly important role in the formation and implementation of a successful post-Kyoto global policy architecture

The development and neural basis of referential gaze perception

Infants are sensitive to the referential information conveyed by others’ eye gaze, which could be one of the developmental foundations of theory of mind. To investigate the neural correlates of gaze–object relations, we recorded ERPs from adults and 9-month-old infants while they watched scenes containing gaze shifts either towards or away from the location of a preceding object. In adults, object-incongruent gaze shifts elicited enhanced ERP amplitudes over the occipito-temporal area (N330). In infants, a similar posterior ERP component (N290) was greater for object-incongruent gaze shifts, which suggests that by the age of 9 months infants encode referential information of gaze in a similar way to adults. In addition, in infants we observed an early frontal ERP component (anterior N200), which showed higher amplitude in response to the perception of object-congruent gaze shifts. This component may reflect fast-track processing of socially relevant information, such as the detection of communicative or informative situations, and could form a developmental foundation for attention sharing, social learning and theory of mind

Model networks of end‐linked polydimethylsiloxane chains. II. Viscoelastic losses

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/71107/2/JCPSA6-68-4-2010-1.pd

Observations of the 6 Centimeter Lines of OH in Evolved (OH/IR) Stars

Recent observational and theoretical advances have called into question traditional OH maser pumping models in evolved (OH/IR) stars. The detection of excited-state OH lines would provide additional constraints to discriminate amongst these theoretical models. In this Letter, we report on VLA observations of the 4750 MHz and 4765 MHz lines of OH toward 45 sources, mostly evolved stars. We detect 4765 MHz emission in the star forming regions Mon R2 and LDN 1084, but we do not detect excited-state emission in any evolved stars. The flux density and velocity of the 4765 MHz detection in Mon R2 suggests that a new flaring event has begun.Comment: 4 pages, to appear in ApJ

Novel natural withanolides induce apoptosis and inhibit migration of neuroblastoma cells through down regulation of N-myc and suppression of Akt/mTOR/NF-κB activation

Despite recent advances in intensive chemotherapy treatments, long-term success is achieved in less than 30% of children with high-risk neuroblastoma (NB). Key regulatory pathways including the PI3K/Akt, mTOR and NF-κB are implicated in the pathogenesis of NB. Although drugs targeting these individual pathways are in clinical trials, they are not effective due to the activation of compensatory mechanisms. We have previously reported that natural novel withanolides from Physalis longifolia can potently inhibit these key regulatory pathways simultaneously. In the present study, we examined the efficacy and mechanisms through which novel withanolides and their acetate derivatives (WGA-TA and WGB-DA) from P.longifolia kill NB cells. The results from the study demonstrated that our novel acetate derivatives are highly effective in inhibiting the proliferation, shifting the cell cycle and inducing apoptosis in a dose dependent manner. Analysis of oncogenic pathway proteins targeted by withanolides indicated induction of heat shock response due to oxidative stress. Dose dependent decrease in clients of HSP90 chaperone function due to suppression of Akt, mTOR, and NF-κB pathways led to decrease in the expressions of target genes such as cyclin D1, N-myc and Survivin. Additionally, there was a dose dependent attenuation of the migration and invasion of NB cells. Furthermore, the lead compound WGA-TA showed significant reduction in tumor growth of NB xenografts. Taken together, these results suggest that withanolides are an effective therapeutic option against NBs