1,601 research outputs found

    On a shape adaptive image ray transform

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    A conventional approach to image analysis is to perform separately feature extraction at a low level (such as edge detection) and follow this with high level feature extraction to determine structure (e.g. by collecting edge points using the Hough transform. The original image Ray Transform (IRT) demonstrated capability to extract structures at a low level. Here we extend the IRT to add shape specificity that makes it select specific shapes rather than just edges, the new capability is achieved by addition of a single parameter that controls which shape is elected by the extended IRT. The extended approach can then perform low-and high-level feature extraction simultaneously. We show how the IRT process can be extended to focus on chosen shapes such as lines and circles. We confirm the new capability by application of conventional methods for exact shape location. We analyze performance with images from the Caltech-256 dataset and show that the new approach can indeed select chosen shapes. Further research could capitalize on the new extraction ability to extend descriptive capability

    Adenovirus vector-specific T cells demonstrate a unique memory phenotype with high proliferative potential and coexpression of CCR5 and integrin α4_4β7_7

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    Background: The Step Study was a randomized trial to reduce HIV infection through vaccination with an adenovirus type 5-based gag/pol/nef construct; analysis following early cessation of the trial revealed an excess of HIV seroconversion in Ad5 seropositive men. This led to the suggestion that the Ad based vector may boost the number of CD4+^+ CCR5+^+ T-cells, target cells for HIV infection. Objectives: We sought to determine the immunophenotype and proliferative capacity of Ad5-specific T cells in the peripheral blood of adult donors to determine whether stimulation with replication defective Ad5 vectors could result in the significant expansion of a CD4+^+ CCR5+^+ T cell subset. Methods: Ad5 specific T cells were identified in the peripheral blood of healthy donors by IFN-y_y secretion assay and proliferative response was measured by CFSE labelling. Cells were analysed by flow cytometry to determine T cell differentiation marker, CCR5 and α4_4β7_7 expression on memory and proliferated cells. Results: Ad5-specific CD4+^+ T cells within healthy adult donors exhibit a unique minimally differentiated memory phenotype with co-expression of CD45RA, CD45RO and CCR7. Stimulation with Ad vector leads to rapid expansion in vitro and a switch to an effector memory phenotype. Both short-term reactivated and proliferating Ad5-specific CD4+ T-cells express the HIV co-receptor CCR5 and the HIV gp120-binding integrin α4_4β7_7. Conclusion: Ad5-specific T cells demonstrate a phenotype and proliferative potential that would support HIV infection; these results are pertinent to the findings of the Step Study and future use of Ad5 as a vaccine vector

    Signatures of unconventional pairing in near-vortex electronic structure of LiFeAs

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    A major question in Fe-based superconductors remains the structure of the pairing, in particular whether it is of unconventional nature. The electronic structure near vortices can serve as a platform for phase-sensitive measurements to answer this question. By solving Bogoliubov-de Gennes equations for LiFeAs, we calculate the energy-dependent local electronic structure near a vortex for different nodeless gap-structure possibilities. At low energies, the local density of states (LDOS) around a vortex is determined by the normal-state electronic structure. However, at energies closer to the gap value, the LDOS can distinguish an anisotropic from a conventional isotropic s-wave gap. We show within our self-consistent calculation that in addition, the local gap profile differs between a conventional and an unconventional pairing. We explain this through admixing of a secondary order parameter within Ginzburg-Landau theory. In-field scanning tunneling spectroscopy near vortices can therefore be used as a real-space probe of the gap structure

    Mean-Field Analysis of Intra-Unit-Cell Order in the Emery Model of the CuO2_2 Plane

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    Motivated by recent experiments on high-TcT_c cuprate superconductors pointing towards intra-unit-cell order in the pseudogap phase, we investigate three distinct intra-unit-cell-ordering possibilities: nematic, nematic-spin-nematic, and current-loop order. The first two are Fermi-surface instabilities involving a spontaneous charge and magnetization imbalance between the two oxygen sites in the unit cell, respectively, while the third describes circulating currents within the unit cell. We analyze the three-band Emery model of a single CuO2_2 layer including various on-site and nearest-neighbor interactions within a self-consistent mean-field approach. We show how these on-site and further-neighbor repulsions suppress or enhance particular IUC orders. In particular, we show that the attractive interactions necessary for nematic and nematic-spin-nematic orders in one-band models have their natural microscopic origin in the O-O on-site and nearest-neighbor repulsions in the three-band model. Finally, we find that while the nematic and nematic-spin-nematic orders cannot coexist in this framework, the loop-current order can coexist with nematic order

    Spin-Orbit Coupling in LaAlO3_3/SrTiO3_3 interfaces: Magnetism and Orbital Ordering

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    The combination of Rashba spin-orbit coupling and electron correlations can induce unusual phenomena in the metallic interface between SrTiO3_3 and LaAlO3_3. We consider effects of Rashba spin-orbit coupling at this interface in the context of the recent observation of anisotropic magnetism. Firstly, we show how Rashba spin-orbit coupling in a system near a band-edge can account for the observed magnetic anisotropy. Secondly, we investigate the coupling between in-plane magnetic-moment anisotropy and nematicity in the form of an orbital imbalance between dxz_{xz} / dyz_{yz} orbitals. We estimate this coupling to be substantial in the low electron density regime. Such an orbital ordering can affect magneto transport
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