18 research outputs found

    A Note on IBE Performance of a Practical Application

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    Every user can be identified online by a unique string used for email or nickname on some of the many platforms out there. IBE systems propose a simple cryptosystem in which the public key system can be omitted by using the unique string as public identification. In this paper we present a minimal email application that uses Clifford Cocks’ proposed IBE scheme. We analyze the impact of using it inside our application and how it can be improved to better fit the need of nowadays applications

    ANIMAL BIODIVERSITY CONSERVATION, A KEY OF SUSTAINABLE AGRICULTURE. CASE STUDY: THE ROMANIAN PINZGAU BREED IN TRANSILVANIA REGION

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    Abstract Pinzgau breed or Pinzgauer is called after its region of origin . These things are the main reasons why race should be kept in a form of active conservation. Moreover, in order to preserve the tradition and traditional products in Romania, is required to maintain this breed and even the formation of its national park

    Investigation of hospital discharge cases and SARS-CoV-2 introduction into Lothian care homes

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    Background The first epidemic wave of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) in Scotland resulted in high case numbers and mortality in care homes. In Lothian, over one-third of care homes reported an outbreak, while there was limited testing of hospital patients discharged to care homes. Aim To investigate patients discharged from hospitals as a source of SARS-CoV-2 introduction into care homes during the first epidemic wave. Methods A clinical review was performed for all patients discharges from hospitals to care homes from 1st March 2020 to 31st May 2020. Episodes were ruled out based on coronavirus disease 2019 (COVID-19) test history, clinical assessment at discharge, whole-genome sequencing (WGS) data and an infectious period of 14 days. Clinical samples were processed for WGS, and consensus genomes generated were used for analysis using Cluster Investigation and Virus Epidemiological Tool software. Patient timelines were obtained using electronic hospital records. Findings In total, 787 patients discharged from hospitals to care homes were identified. Of these, 776 (99%) were ruled out for subsequent introduction of SARS-CoV-2 into care homes. However, for 10 episodes, the results were inconclusive as there was low genomic diversity in consensus genomes or no sequencing data were available. Only one discharge episode had a genomic, time and location link to positive cases during hospital admission, leading to 10 positive cases in their care home. Conclusion The majority of patients discharged from hospitals were ruled out for introduction of SARS-CoV-2 into care homes, highlighting the importance of screening all new admissions when faced with a novel emerging virus and no available vaccine

    SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway

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    Vaccines based on the spike protein of SARS-CoV-2 are a cornerstone of the public health response to COVID-19. The emergence of hypermutated, increasingly transmissible variants of concern (VOCs) threaten this strategy. Omicron (B.1.1.529), the fifth VOC to be described, harbours multiple amino acid mutations in spike, half of which lie within the receptor-binding domain. Here we demonstrate substantial evasion of neutralization by Omicron BA.1 and BA.2 variants in vitro using sera from individuals vaccinated with ChAdOx1, BNT162b2 and mRNA-1273. These data were mirrored by a substantial reduction in real-world vaccine effectiveness that was partially restored by booster vaccination. The Omicron variants BA.1 and BA.2 did not induce cell syncytia in vitro and favoured a TMPRSS2-independent endosomal entry pathway, these phenotypes mapping to distinct regions of the spike protein. Impaired cell fusion was determined by the receptor-binding domain, while endosomal entry mapped to the S2 domain. Such marked changes in antigenicity and replicative biology may underlie the rapid global spread and altered pathogenicity of the Omicron variant

    Study of the main body dimensions that are used in the selection process, in the reproductive nucleus of the Nonius horse from Izvin studfarm

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    Regarding to a population, the average of phenotypic value is equal with average of genotypic value and that minds that the study of average performances in a population have a huge importance. So, the studies of the average values of characters offer us an idea about the population genetic level. This study have the principal purpose to analyse main body dimensions who are used in selection process: withers height, thoracyc perimether and cannon bone perimether, through the integration of individs in an evaluation class, in accordance with selection methodology. The biological material is represented by 35 Nonius horses, 4 males and 31 females, at different ages, owned by Izvin stood farm, representing the entire reproductive nucleus. The average performances of characters are presented in the paper. We can observe a small grade of variability with some differences between sexes. The average performances of the characters are between characteristic limits of the breed

    Study about thoracic perimeter average performances in Romanian Hucul horse breed – Prislop bloodline

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    Study of average performances in a population have a huge importance because, regarding a population, the average of phenotypic value is equal with average of genotypic value. So, the studies of the average value of characters offer us an idea about the population genetic level. The biological material is represented by 93 hucul horse from Prislop bloodline divided in 3 stallion families analyzed at 18, 30 and 42 months old, owned by Lucina hucul stood farm. The average performances for thoracic perimeter was 148.55 cm. at 18 months, 160.44 at 30 months old and 167.77 cm. at 42 months old. We can observe a good growth rate from one age to another and a small differences between sexes. The average performances of the character are between characteristic limits of the breed

    IMPLICATIONS AND CONSTRAINTS OF PERIODONTAL IMPLANTATION FOR ORTHODONTIC PURPOSES IN THE CONTEXT OF DIABETES AND OTHER ASSOCIATED COMORBIDITIES. REVIEW.

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    Diabetes mellitus and periodontal disease are among the most common chronic diseases of mankind and, remarkably, they share many common features. The most common forms of periodontal diseases, gingivitis and periodontitis, are characterized by a microbially driven series of host responses that lead to periodontal tissue damage.The host response is central to the development of periodontitis, as it is to the development and progression of several human chronic diseases, including diabetes mellitus. In the next sections we will review the main features of diabetes mellitus, with the main focus being the association between type 2 diabetes mellitus and periodontitis. Peri-implant diseases are infectious conditions affecting dental implants, ranging from peri-implant mucositis, which is an inflammatory lesion of the peri-implant mucosa, to peri-implantitis, which also affects the supporting bone. As well as potentially sharing some similar risk factors, diabetes mellitus and periodontal disease patients have exceptionally similar tendencies to develop comorbidities that tend to cluster in the same individuals. Attention to the patient’s medical history is one of the cornerstones for efforts in the prevention of periodontal and peri-implant diseases
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